Chemokine Receptor-Specific Antibodies in Cancer Immunotherapy: Achievements and Challenges
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Chemokine Receptor-Specific Antibodies in Cancer Immunotherapy: Achievements and Challenges
Authors
Keywords
-
Journal
Frontiers in Immunology
Volume 6, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2015-01-30
DOI
10.3389/fimmu.2015.00012
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Increase in Activated Treg in TIL in Lung Cancer and In Vitro Depletion of Treg by ADCC Using an Antihuman CCR4 mAb (KM2760)
- (2015) Koji Kurose et al. Journal of Thoracic Oncology
- Chemokines in tumor progression and metastasis
- (2015) Purvaba J. Sarvaiya et al. Oncotarget
- Phenotypic and Functional Delineation of Murine CX3CR1+ Monocyte-Derived Cells in Ovarian Cancer
- (2015) Kevin M. Hart et al. NEOPLASIA
- CXCR4 Inhibition with AMD3100 Sensitizes Prostate Cancer to Docetaxel Chemotherapy
- (2015) Urszula M. Domanska et al. NEOPLASIA
- CCR1-mediated accumulation of myeloid cells in the liver microenvironment promoting mouse colon cancer metastasis
- (2014) Hideyo Hirai et al. CLINICAL & EXPERIMENTAL METASTASIS
- CXCR4 antibody treatment suppresses metastatic spread to the lung of intratibial human osteosarcoma xenografts in mice
- (2014) Patrick Brennecke et al. CLINICAL & EXPERIMENTAL METASTASIS
- Anti-CCR4 Monoclonal Antibody Mogamulizumab for the Treatment of EBV-Associated T- and NK-Cell Lymphoproliferative Diseases
- (2014) T. Kanazawa et al. CLINICAL CANCER RESEARCH
- Reduction of Regulatory T Cells by Mogamulizumab, a Defucosylated Anti-CC Chemokine Receptor 4 Antibody, in Patients with Aggressive/Refractory Mycosis Fungoides and Sezary Syndrome
- (2014) X. Ni et al. CLINICAL CANCER RESEARCH
- The perspective of immunotherapy
- (2014) Christian U. Blank CURRENT OPINION IN ONCOLOGY
- CCR4 and its ligands: from bench to bedside
- (2014) O. Yoshie et al. INTERNATIONAL IMMUNOLOGY
- CCR7: Roles in cancer cell dissemination, migration and metastasis formation
- (2014) Daniel F. Legler et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Immunotherapy of B-cell non-Hodgkin lymphoma by targeting the chemokine receptor CXCR5 in a preclinical mouse model
- (2014) Hossein Panjideh et al. INTERNATIONAL JOURNAL OF CANCER
- Effect of anti-CCR4 monoclonal antibody (mogamulizumab) on adult T-cell leukemia-lymphoma: Cutaneous adverse reactions may predict the prognosis
- (2014) Kentaro Yonekura et al. JOURNAL OF DERMATOLOGY
- The role of immunotherapy in solid tumors: report from the Campania Society of Oncology Immunotherapy (SCITO) meeting, Naples 2014
- (2014) Paolo A Ascierto et al. Journal of Translational Medicine
- Antitumor effects of a monoclonal antibody to human CCR9 in leukemia cell xenografts
- (2014) Sonia Chamorro et al. mAbs
- Role of Fractalkine/CX3CL1 and Its Receptor in the Pathogenesis of Inflammatory and Malignant Diseases with Emphasis on B Cell Malignancies
- (2014) Elisa Ferretti et al. MEDIATORS OF INFLAMMATION
- CCR6 Is a Prognostic Marker for Overall Survival in Patients with Colorectal Cancer, and Its Overexpression Enhances Metastasis In Vivo
- (2014) Jinlin Liu et al. PLoS One
- Fully Human Antagonistic Antibodies against CCR4 Potently Inhibit Cell Signaling and Chemotaxis
- (2014) Urs B. Hagemann et al. PLoS One
- Expression of the C-C Chemokine Receptor 7 Mediates Metastasis of Breast Cancer to the Lymph Nodes in Mice
- (2014) Heather D. Cunningham et al. Translational Oncology
- Chemokines and chemokine receptors required for optimal responses to anticancer chemotherapy
- (2014) Yuting Ma et al. OncoImmunology
- Trial Watch
- (2014) Erika Vacchelli et al. OncoImmunology
- Successful treatment with anti-CC chemokine receptor 4 MoAb of relapsed adult T-cell leukemia/lymphoma after umbilical cord blood transplantation
- (2013) Y Ito et al. BONE MARROW TRANSPLANTATION
- The chemokine system, and its CCR5 and CXCR4 receptors, as potential targets for personalized therapy in cancer
- (2013) Polina Weitzenfeld et al. CANCER LETTERS
- CCL2/CCR2-Dependent Recruitment of Functional Antigen-Presenting Cells into Tumors upon Chemotherapy
- (2013) Yuting Ma et al. CANCER RESEARCH
- Stevens-Johnson Syndrome associated with mogamulizumab treatment of adult T-cell leukemia / lymphoma
- (2013) Takashi Ishida et al. CANCER SCIENCE
- Agonistic CD40 Antibodies and Cancer Therapy
- (2013) R. H. Vonderheide et al. CLINICAL CANCER RESEARCH
- Checkpoint blocking antibodies in cancer immunotherapy
- (2013) Chrisann Kyi et al. FEBS LETTERS
- Loss of SMAD4 From Colorectal Cancer Cells Promotes CCL15 Expression to Recruit CCR1+ Myeloid Cells and Facilitate Liver Metastasis
- (2013) Yoshiro Itatani et al. GASTROENTEROLOGY
- Reactivation of hepatitis B virus in a patient with adult T-cell leukemia-lymphoma receiving the anti-CC chemokine receptor 4 antibody mogamulizumab
- (2013) Nobuaki Nakano et al. HEPATOLOGY RESEARCH
- Diffuse panbronchiolitis after humanized anti-CCR4 monoclonal antibody therapy for relapsed adult T-cell leukemia/lymphoma
- (2013) Koji Kato et al. INTERNATIONAL JOURNAL OF HEMATOLOGY
- Llama-derived Single Variable Domains (Nanobodies) Directed against Chemokine Receptor CXCR7 Reduce Head and Neck Cancer Cell Growthin Vivo
- (2013) David Maussang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The oxysterol–CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils
- (2013) Laura Raccosta et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Anti-CCR7 therapy exerts a potent anti-tumor activity in a xenograft model of human mantle cell lymphoma
- (2013) Beatriz Somovilla-Crespo et al. Journal of Hematology & Oncology
- Chemokine receptor CX3CR1 contributes to macrophage survival in tumor metastasis
- (2013) Jiao Zheng et al. Molecular Cancer
- Targeting CXCR2 Enhances Chemotherapeutic Response, Inhibits Mammary Tumor Growth, Angiogenesis, and Lung Metastasis
- (2013) B. Sharma et al. MOLECULAR CANCER THERAPEUTICS
- Inflammatory chemokines and metastasis—tracing the accessory
- (2013) L Borsig et al. ONCOGENE
- The microenvironment in chronic lymphocytic leukemia (CLL) and other B cell malignancies: Insight into disease biology and new targeted therapies
- (2013) Jan A. Burger et al. SEMINARS IN CANCER BIOLOGY
- Small Molecule Inhibitors of CXCR4
- (2013) Bikash Debnath et al. Theranostics
- Halting metastasis through CXCR4 inhibition
- (2012) Deborah M. Ramsey et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- CXCR2 Expression in Tumor Cells Is a Poor Prognostic Factor and Promotes Invasion and Metastasis in Lung Adenocarcinoma
- (2012) P. Saintigny et al. CANCER RESEARCH
- CCR5 Antagonist Blocks Metastasis of Basal Breast Cancer Cells
- (2012) M. Velasco-Velazquez et al. CANCER RESEARCH
- T-Regulatory Cells: Key Players in Tumor Immune Escape and Angiogenesis
- (2012) A. Facciabene et al. CANCER RESEARCH
- BMS-936564/MDX-1338: A Fully Human Anti-CXCR4 Antibody Induces Apoptosis In Vitro and Shows Antitumor Activity In Vivo in Hematologic Malignancies
- (2012) M. R. Kuhne et al. CLINICAL CANCER RESEARCH
- Chemokine receptor trio: CXCR3, CXCR4 and CXCR7 crosstalk via CXCL11 and CXCL12
- (2012) Anup Kumar Singh et al. CYTOKINE & GROWTH FACTOR REVIEWS
- The future of antibodies as cancer drugs
- (2012) Janice M. Reichert et al. DRUG DISCOVERY TODAY
- A review on CXCR4/CXCL12 axis in oncology: No place to hide
- (2012) Urszula M. Domanska et al. EUROPEAN JOURNAL OF CANCER
- Therapeutic Antibodies Against Cancer
- (2012) Mark J. Adler et al. HEMATOLOGY-ONCOLOGY CLINICS OF NORTH AMERICA
- Current status of chemokine receptor inhibitors in development
- (2012) Marcello Allegretti et al. IMMUNOLOGY LETTERS
- The role of CXCR3 and CXCR4 in colorectal cancer metastasis
- (2012) Teppei Murakami et al. INTERNATIONAL JOURNAL OF CANCER
- Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis
- (2012) Thomas Jamieson et al. JOURNAL OF CLINICAL INVESTIGATION
- Altered CXCR3 isoform expression regulates prostate cancer cell migration and invasion
- (2012) Qian Wu et al. Molecular Cancer
- Humanization of an Anti-CCR4 Antibody That Kills Cutaneous T-Cell Lymphoma Cells and Abrogates Suppression by T-Regulatory Cells
- (2012) D.-K. Chang et al. MOLECULAR CANCER THERAPEUTICS
- CC chemokine ligand 7 expression in liver metastasis of colorectal cancer
- (2012) YONG BEOM CHO et al. ONCOLOGY REPORTS
- Human Anti-CCR4 Minibody Gene Transfer for the Treatment of Cutaneous T-Cell Lymphoma
- (2012) Thomas Han et al. PLoS One
- Molecular networks that regulate cancer metastasis
- (2012) Daniela Spano et al. SEMINARS IN CANCER BIOLOGY
- The pros and cons of chemokines in tumor immunology
- (2012) Antonella Viola et al. TRENDS IN IMMUNOLOGY
- CXCR7 impact on CXCL12 biology and disease
- (2012) Lorena Sánchez-Martín et al. TRENDS IN MOLECULAR MEDICINE
- Targeting Chemokine Receptor CCR4 in Adult T-Cell Leukemia-Lymphoma and Other T-Cell Lymphomas
- (2012) Kensei Tobinai et al. Current Hematologic Malignancy Reports
- Overexpression of CXCL5 Is Associated With Poor Survival in Patients With Pancreatic Cancer
- (2011) Aihua Li et al. AMERICAN JOURNAL OF PATHOLOGY
- CCL18 from Tumor-Associated Macrophages Promotes Breast Cancer Metastasis via PITPNM3
- (2011) Jingqi Chen et al. CANCER CELL
- The role of chemokines and their receptors in angiogenesis
- (2011) Friedemann Kiefer et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Plerixafor
- (2011) Gillian M. Keating DRUGS
- Chemokines as targets for therapy
- (2011) Alexandre Garin et al. EXPERIMENTAL CELL RESEARCH
- Chemokines in health and disease
- (2011) Dayanidhi Raman et al. EXPERIMENTAL CELL RESEARCH
- Chemokines in tumor development and progression
- (2011) Naofumi Mukaida et al. EXPERIMENTAL CELL RESEARCH
- CCL25 mediates migration, invasion and matrix metalloproteinase expression by breast cancer cells in a CCR9-dependent fashion
- (2011) Lillard INTERNATIONAL JOURNAL OF ONCOLOGY
- Notch1 regulates chemotaxis and proliferation by controlling the CC-chemokine receptors 5 and 9 in T cell acute lymphoblastic leukaemia
- (2011) Leonardo Mirandola et al. JOURNAL OF PATHOLOGY
- The chemokine system and cancer
- (2011) Frances R Balkwill JOURNAL OF PATHOLOGY
- The expression of CXCL12 and CXCR4 in gastric cancer and their correlation to lymph node metastasis
- (2011) Jieer Ying et al. MEDICAL ONCOLOGY
- The novel chemokine receptor CXCR7 regulates trans-endothelial migration of cancer cells
- (2011) Brian A Zabel et al. Molecular Cancer
- Fractalkine Receptor CX3CR1 Is Expressed in Epithelial Ovarian Carcinoma Cells and Required for Motility and Adhesion to Peritoneal Mesothelial Cells
- (2011) M. Kim et al. MOLECULAR CANCER RESEARCH
- Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells
- (2011) Andrea Facciabene et al. NATURE
- Monoclonal antibodies for the treatment of asthma
- (2011) Matthew C. Catley et al. PHARMACOLOGY & THERAPEUTICS
- CCL5 Neutralization Restricts Cancer Growth and Potentiates the Targeting of PDGFRβ in Colorectal Carcinoma
- (2011) Béatrice Cambien et al. PLoS One
- CXCL12 / CXCR4 / CXCR7 chemokine axis and cancer progression
- (2010) Xueqing Sun et al. CANCER AND METASTASIS REVIEWS
- CXCL12, CXCR4 and CXCR7 expression in brain metastases
- (2010) Andrea Salmaggi et al. CANCER BIOLOGY & THERAPY
- Histomorphologic parameters and CXCR4 mRNA and protein expression in sentinel node melanoma metastasis are correlated to clinical outcome
- (2010) Renato Franco et al. CANCER BIOLOGY & THERAPY
- The Chemokine Receptor CXCR7 Is Highly Expressed in Human Glioma Cells and Mediates Antiapoptotic Effects
- (2010) K. Hattermann et al. CANCER RESEARCH
- Defucosylated Humanized Anti-CCR4 Monoclonal Antibody KW-0761 as a Novel Immunotherapeutic Agent for Adult T-cell Leukemia/Lymphoma
- (2010) T. Ishii et al. CLINICAL CANCER RESEARCH
- Human glioblastoma tumours and neural cancer stem cells express the chemokine CX3CL1 and its receptor CX3CR1
- (2010) Marco Erreni et al. EUROPEAN JOURNAL OF CANCER
- Chemokines in cancer related inflammation
- (2010) Paola Allavena et al. EXPERIMENTAL CELL RESEARCH
- Targeting CXCR1/CXCR2 receptor antagonism in malignant melanoma
- (2010) Bhawna Sharma et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Overlapping and distinct role of CXCR7-SDF-1/ITAC and CXCR4-SDF-1 axes in regulating metastatic behavior of human rhabdomyosarcomas
- (2010) Katarzyna Grymula et al. INTERNATIONAL JOURNAL OF CANCER
- Phase I Study of KW-0761, a Defucosylated Humanized Anti-CCR4 Antibody, in Relapsed Patients With Adult T-Cell Leukemia-Lymphoma and Peripheral T-Cell Lymphoma
- (2010) Kazuhito Yamamoto et al. JOURNAL OF CLINICAL ONCOLOGY
- Role of CX3CR1/CX3CL1 axis in primary and secondary involvement of the nervous system by cancer
- (2010) Federica Marchesi et al. JOURNAL OF NEUROIMMUNOLOGY
- CXCR4 and cancer
- (2010) Bungo Furusato et al. PATHOLOGY INTERNATIONAL
- CCR10 and CCL27 are overexpressed in cutaneous squamous cell carcinoma
- (2010) Hiromichi Kai et al. PATHOLOGY RESEARCH AND PRACTICE
- CXCR7 Functions as a Scavenger for CXCL12 and CXCL11
- (2010) Ulrike Naumann et al. PLoS One
- Elucidating the CXCL12/CXCR4 Signaling Network in Chronic Lymphocytic Leukemia through Phosphoproteomics Analysis
- (2010) Morgan O'Hayre et al. PLoS One
- CXCR4 nanobodies (VHH-based single variable domains) potently inhibit chemotaxis and HIV-1 replication and mobilize stem cells
- (2010) S. Jahnichen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inactivation of chemokine (C-C motif) receptor 1 (CCR1) suppresses colon cancer liver metastasis by blocking accumulation of immature myeloid cells in a mouse model
- (2010) T. Kitamura et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Induction of Lymphoidlike Stroma and Immune Escape by Tumors That Express the Chemokine CCL21
- (2010) J. D. Shields et al. SCIENCE
- Chemokines and chemokine receptors: new insights into cancer-related inflammation
- (2010) Gwendal Lazennec et al. TRENDS IN MOLECULAR MEDICINE
- Blockade of CCR4 in a humanized model of asthma reveals a critical role for DC-derived CCL17 and CCL22 in attracting Th2 cells and inducing airway inflammation
- (2009) F. Perros et al. ALLERGY
- Hepatic Stellate Cells Promote Liver Metastasis of Colon Cancer Cells by the Action of SDF-1/CXCR4 Axis
- (2009) Ryo Matsusue et al. ANNALS OF SURGICAL ONCOLOGY
- CXCR4 inhibitor AMD3100 disrupts the interaction of multiple myeloma cells with the bone marrow microenvironment and enhances their sensitivity to therapy
- (2009) A. K. Azab et al. BLOOD
- High expression of CXCR4 may predict poor survival in resected pancreatic adenocarcinoma
- (2009) R Maréchal et al. BRITISH JOURNAL OF CANCER
- CXCR1 and CXCR2 enhances human melanoma tumourigenesis, growth and invasion
- (2009) S Singh et al. BRITISH JOURNAL OF CANCER
- Organ-specific inhibition of metastatic colon carcinoma by CXCR3 antagonism
- (2009) B Cambien et al. BRITISH JOURNAL OF CANCER
- Therapeutic antibodies: successes, limitations and hopes for the future
- (2009) Patrick Chames et al. BRITISH JOURNAL OF PHARMACOLOGY
- Higher expression of chemokine receptorCXCR7is linked to early and metastatic recurrence in pathological stage I nonsmall cell lung cancer
- (2009) Shotaro Iwakiri et al. CANCER
- The CXCR4/CXCL12 axis in endometrial cancer
- (2009) Stefania Gelmini et al. CLINICAL & EXPERIMENTAL METASTASIS
- The chemokine system in cancer biology and therapy
- (2009) Alberto Mantovani et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Emerging roles of chemokines in prostate cancer
- (2009) David Vindrieux et al. ENDOCRINE-RELATED CANCER
- CXCL8 and its cognate receptors in melanoma progression and metastasis
- (2009) Seema Singh et al. Future Oncology
- CXC-chemokine/CXCR2 biological axis promotes angiogenesis in vitro and in vivo in pancreatic cancer
- (2009) Yoichi Matsuo et al. INTERNATIONAL JOURNAL OF CANCER
- Antagonism of chemokine receptor CXCR3 inhibits osteosarcoma metastasis to lungs
- (2009) Emmanuelle Pradelli et al. INTERNATIONAL JOURNAL OF CANCER
- Chemokine (C-C Motif) Ligand 2 Engages CCR2+Stromal Cells of Monocytic Origin to Promote Breast Cancer Metastasis to Lung and Bone
- (2009) Xin Lu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Defucosylated Anti-CCR4 Monoclonal Antibody Exerts Potent ADCC against Primary ATLL Cells Mediated by Autologous Human Immune Cells in NOD/Shi-scid, IL-2R null Mice In Vivo
- (2009) A. Ito et al. JOURNAL OF IMMUNOLOGY
- Chemokine Receptors in T-Cell-Mediated Diseases of the Skin
- (2009) Anke S. Lonsdorf et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- First Results for Agents Targeting Cancer-Related Inflammation
- (2009) Ken Garber JNCI-Journal of the National Cancer Institute
- CCR7 signalling as an essential regulator of CNS infiltration in T-cell leukaemia
- (2009) Silvia Buonamici et al. NATURE
- Tumor-mediated liver X receptor-α activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses
- (2009) Eduardo J Villablanca et al. NATURE MEDICINE
- CCR5 monoclonal antibodies for HIV-1 therapy
- (2009) William C Olson et al. Current Opinion in HIV and AIDS
- Role of Chemokine Network in the Development and Progression of Ovarian Cancer: A Potential Novel Pharmacological Target
- (2009) Federica Barbieri et al. Journal of Oncology
- Treatment with anti-CC chemokine receptor 3 monoclonal antibody or dexamethasone inhibits the migration and differentiation of bone marrow CD34+progenitor cells in an allergic mouse model
- (2008) S. Ben et al. ALLERGY
- Modulation of CCR2 in rheumatoid arthritis: A double‐blind, randomized, placebo‐controlled clinical trial
- (2008) Clarissa E. Vergunst et al. ARTHRITIS AND RHEUMATISM
- Chemokines and cancer: migration, intracellular signalling and intercellular communication in the microenvironment
- (2008) Morgan O'Hayre et al. BIOCHEMICAL JOURNAL
- Chemokine-mediated rapid turnover of myeloid-derived suppressor cells in tumor-bearing mice
- (2008) Y. Sawanobori et al. BLOOD
- Abrogation of TGFβ Signaling in Mammary Carcinomas Recruits Gr-1+CD11b+ Myeloid Cells that Promote Metastasis
- (2008) Li Yang et al. CANCER CELL
- The role of CXC chemokines and their receptors in cancer
- (2008) Jo Vandercappellen et al. CANCER LETTERS
- The inflammatory chemokines CCL2 and CCL5 in breast cancer
- (2008) Gali Soria et al. CANCER LETTERS
- The involvement of the fractalkine receptor in the transmigration of neuroblastoma cells through bone-marrow endothelial cells
- (2008) Ido Nevo et al. CANCER LETTERS
- The Chemokine Receptor CX3CR1 Is Involved in the Neural Tropism and Malignant Behavior of Pancreatic Ductal Adenocarcinoma
- (2008) Federica Marchesi et al. CANCER RESEARCH
- Chemokine receptor CXCR4 expression and prognosis in patients with metastatic prostate cancer
- (2008) Takuya Akashi et al. CANCER SCIENCE
- Activation of MCP-1/CCR2 axis promotes prostate cancer growth in bone
- (2008) Yi Lu et al. CLINICAL & EXPERIMENTAL METASTASIS
- Activation of CCR9/CCL25 in Cutaneous Melanoma Mediates Preferential Metastasis to the Small Intestine
- (2008) F. F. Amersi et al. CLINICAL CANCER RESEARCH
- Early postnatal lethality and cardiovascular defects in CXCR7-deficient mice
- (2008) Han Gerrits et al. GENESIS
- CXCL8/IL-8 and CXCL12/SDF-1α co-operatively promote invasiveness and angiogenesis in pancreatic cancer
- (2008) Yoichi Matsuo et al. INTERNATIONAL JOURNAL OF CANCER
- CXCR7, CXCR4 and CXCL12: An eccentric trio?
- (2008) Marcus Thelen et al. JOURNAL OF NEUROIMMUNOLOGY
- New insights on the role of CXCR4 in cancer metastasis
- (2008) A Zlotnik JOURNAL OF PATHOLOGY
- The CCR9–CCL25 axis mediates melanoma metastasis to the small intestine
- (2008) Joost van den Oord Nature clinical practice. Oncology
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More