The Extended Family of CD1d-Restricted NKT Cells: Sifting through a Mixed Bag of TCRs, Antigens, and Functions

Type II NKT-TFH cells against Gaucher lipids regulate B-cell immunity and inflammation

(2014) S. Nair et al.   BLOOD

The adaptor protein SAP regulates type II NKT-cell development, cytokine production, and cytotoxicity against lymphoma

(2014) Xiufang Weng et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-13Rα2-bearing, type II NKT cells reactive to sulfatide self-antigen populate the mucosa of ulcerative colitis

(2014) Ivan J Fuss et al.   GUT

The Identification of the Endogenous Ligands of Natural Killer T Cells Reveals the Presence of Mammalian α-Linked Glycosylceramides

(2014) Lisa Kain et al.   IMMUNITY

IL-10–producing NKT10 cells are a distinct regulatory invariant NKT cell subset

(2014) Duygu Sag et al.   JOURNAL OF CLINICAL INVESTIGATION

The molecular bases of δ/αβ T cell–mediated antigen recognition

(2014) Daniel G. Pellicci et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Involvement of Secretory and Endosomal Compartments in Presentation of an Exogenous Self-Glycolipid to Type II NKT Cells

(2014) K. C. Roy et al.   JOURNAL OF IMMUNOLOGY

NKT Cells in Tumor Immunity: Opposing Subsets Define a New Immunoregulatory Axis

(2014) J. A. Berzofsky et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: The Mechanism of Invariant NKT Cell Responses to Viral Danger Signals

(2014) A. J. Tyznik et al.   JOURNAL OF IMMUNOLOGY

Recognition of Lysophosphatidylcholine by Type II NKT Cells and Protection from an Inflammatory Liver Disease

(2014) Igor Maricic et al.   JOURNAL OF IMMUNOLOGY

Dendritic Cells and Anergic Type I NKT Cells Play a Crucial Role in Sulfatide-Mediated Immune Regulation in Experimental Autoimmune Encephalomyelitis

(2014) I. Maricic et al.   JOURNAL OF IMMUNOLOGY

Antigen-Dependent versus -Independent Activation of Invariant NKT Cells during Infection

(2014) K. L. Holzapfel et al.   JOURNAL OF IMMUNOLOGY

Regulatory iNKT cells lack expression of the transcription factor PLZF and control the homeostasis of Treg cells and macrophages in adipose tissue

(2014) Lydia Lynch et al.   NATURE IMMUNOLOGY

Polyclonal type II natural killer T cells require PLZF and SAP for their development and contribute to CpG-mediated antitumor response

(2014) J. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of iNKT cells by a distinct constituent of the endogenous glucosylceramide fraction

(2014) Patrick J. Brennan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Administration of Sulfatide to Ameliorate Type I Diabetes in Non-Obese Diabetic Mice

(2014) S. Rhost et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

iNKT Cell Production of GM-CSF Controls Mycobacterium tuberculosis

(2014) Alissa C. Rothchild et al.   PLoS Pathogens

NKT Cell Networks in the Regulation of Tumor Immunity

(2014) Faith C. Robertson et al.   Frontiers in Immunology

Natural Killer T cell obsession with self-antigens

(2013) Laurent Gapin et al.   CURRENT OPINION IN IMMUNOLOGY

A Long-Playing CD about the γδ TCR Repertoire

(2013) Adrian Hayday et al.   IMMUNITY

Crystal Structure of Vδ1 T Cell Receptor in Complex with CD1d-Sulfatide Shows MHC-like Recognition of a Self-Lipid by Human γδ T Cells

(2013) Adrienne M. Luoma et al.   IMMUNITY

Sulfatide Attenuates Experimental Staphylococcus aureus Sepsis through a CD1d-Dependent Pathway

(2013) Jakub Kwiecinski et al.   INFECTION AND IMMUNITY

Cutting Edge: CD1d Restriction and Th1/Th2/Th17 Cytokine Secretion by Human V 3 T Cells

(2013) B. A. Mangan et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: IL-25 Elicits Innate Lymphoid Type 2 and Type II NKT Cells That Regulate Obesity in Mice

(2013) E. Hams et al.   JOURNAL OF IMMUNOLOGY

The role of invariant natural killer T cells in microbial immunity

(2013) Yuki Kinjo et al.   JOURNAL OF INFECTION AND CHEMOTHERAPY

Role of type 1 natural killer T cells in pulmonary immunity

(2013) C Paget et al.   Mucosal Immunology

CD1d-lipid antigen recognition by the γδ TCR

(2013) Adam P Uldrich et al.   NATURE IMMUNOLOGY

Steady-state production of IL-4 modulates immunity in mouse strains and is determined by lineage diversity of iNKT cells

(2013) You Jeong Lee et al.   NATURE IMMUNOLOGY

Role of natural killer T lymphocytes during helminthic infection

(2013) C. Faveeuw et al.   Parasite

Recognition of microbial and mammalian phospholipid antigens by NKT cells with diverse TCRs

(2013) R. V. V. Tatituri et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of novel glycolipid ligands activating a sulfatide-reactive, CD1d-restricted, type II natural killer T lymphocyte

(2012) Sara Rhost et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The majority of CD1d-sulfatide-specific T cells in human blood use a semiinvariant Vδ1 TCR

(2012) Li Bai et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interleukin-22 Is Produced by Invariant Natural Killer T Lymphocytes during Influenza A Virus Infection

(2012) Christophe Paget et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blocking IL-25 signalling protects against gut inflammation in a type-2 model of colitis by suppressing nuocyte and NKT derived IL-13

(2012) Ana Camelo et al.   JOURNAL OF GASTROENTEROLOGY

Mutation of a Positively Charged Cytoplasmic Motif within CD1d Results in Multiple Defects in Antigen Presentation to NKT Cells

(2012) J. H. Shin et al.   JOURNAL OF IMMUNOLOGY

Follicular Helper NKT Cells Induce Limited B Cell Responses and Germinal Center Formation in the Absence of CD4+ T Cell Help

(2012) E. Tonti et al.   JOURNAL OF IMMUNOLOGY

CD4+ Type II NKT Cells Mediate ICOS and Programmed Death-1-Dependent Regulation of Type 1 Diabetes

(2012) N. Kadri et al.   JOURNAL OF IMMUNOLOGY

Type II NKT cells facilitate Alum-sensing and humoral immunity

(2012) Hemangi B. Shah et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Recognition of CD1d-sulfatide mediated by a type II natural killer T cell antigen receptor

(2012) Onisha Patel et al.   NATURE IMMUNOLOGY

Lower TCR repertoire diversity in Traj18-deficient mice

(2012) Romain Bedel et al.   NATURE IMMUNOLOGY

Type II natural killer T cells use features of both innate-like and conventional T cells to recognize sulfatide self antigens

(2012) Enrico Girardi et al.   NATURE IMMUNOLOGY

Structural basis for the killing of human beta cells by CD8+ T cells in type 1 diabetes

(2012) Anna M Bulek et al.   NATURE IMMUNOLOGY

Hepatitis B virus–induced lipid alterations contribute to natural killer T cell–dependent protective immunity

(2012) Sebastian Zeissig et al.   NATURE MEDICINE

Co-dependents: MR1-restricted MAIT cells and their antimicrobial function

(2012) Marielle C. Gold et al.   NATURE REVIEWS MICROBIOLOGY

Type II NKT Cells Stimulate Diet-Induced Obesity by Mediating Adipose Tissue Inflammation, Steatohepatitis and Insulin Resistance

(2012) Masashi Satoh et al.   PLoS One

NKT Cells Stimulated by Long Fatty Acyl Chain Sulfatides Significantly Reduces the Incidence of Type 1 Diabetes in Nonobese Diabetic Mice

(2012) Lakshmimathy Subramanian et al.   PLoS One

Invariant natural killer T cells as sensors and managers of inflammation

(2012) Luc Van Kaer et al.   TRENDS IN IMMUNOLOGY

The Molecular Basis for Recognition of CD1d/α-Galactosylceramide by a Human Non-Vα24 T Cell Receptor

(2012) Jacinto López-Sagaseta et al.   PLOS BIOLOGY

Development and Function of Invariant Natural Killer T Cells Producing TH2- and TH17-Cytokines

(2012) Hiroshi Watarai et al.   PLOS BIOLOGY

Invariant NKT Cells: Regulation and Function during Viral Infection

(2012) Jennifer A. Juno et al.   PLoS Pathogens

Sulfatide-activated type II NKT cells prevent allergic airway inflammation by inhibiting type I NKT cell function in a mouse model of asthma

(2011) Guqin Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

NKG2D performs two functions in invariant NKT cells: Direct TCR-independent activation of NK-like cytolysis and co-stimulation of activation by CD1d

(2011) Carlotta Kuylenstierna et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Dysregulation of CD1d-Restricted Type II Natural Killer T Cells Leads to Spontaneous Development of Colitis in Mice

(2011) Chia–Min Liao et al.   GASTROENTEROLOGY

A Molecular Basis for NKT Cell Recognition of CD1d-Self-Antigen

(2011) Thierry Mallevaey et al.   IMMUNITY

Innate and cytokine-driven signals, rather than microbial antigens, dominate in natural killer T cell activation during microbial infection

(2011) Manfred Brigl et al.   JOURNAL OF EXPERIMENTAL MEDICINE

A Naive-Like Population of Human CD1d-Restricted T Cells Expressing Intermediate Levels of Promyelocytic Leukemia Zinc Finger

(2011) M. G. Constantinides et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Structural Basis for the Recognition of  -Linked Glycolipid Antigens by Invariant NKT Cells

(2011) E. D. Yu et al.   JOURNAL OF IMMUNOLOGY

Cardiolipin Binds to CD1d and Stimulates CD1d-Restricted    T Cells in the Normal Murine Repertoire

(2011) M. Dieude et al.   JOURNAL OF IMMUNOLOGY

A semi-invariant Vα10+ T cell antigen receptor defines a population of natural killer T cells with distinct glycolipid antigen–recognition properties

(2011) Adam P Uldrich et al.   NATURE IMMUNOLOGY

Recognition of β-linked self glycolipids mediated by natural killer T cell antigen receptors

(2011) Daniel G Pellicci et al.   NATURE IMMUNOLOGY

Invariant natural killer T cells recognize lipid self antigen induced by microbial danger signals

(2011) Patrick J Brennan et al.   NATURE IMMUNOLOGY

Invariant natural killer T cells recognize glycolipids from pathogenic Gram-positive bacteria

(2011) Yuki Kinjo et al.   NATURE IMMUNOLOGY

Identification of Bcl-6-dependent follicular helper NKT cells that provide cognate help for B cell responses

(2011) Pheh-Ping Chang et al.   NATURE IMMUNOLOGY

Invariant natural killer T cells direct B cell responses to cognate lipid antigen in an IL-21-dependent manner

(2011) Irah L King et al.   NATURE IMMUNOLOGY

V 2 natural killer T cell antigen receptor-mediated recognition of CD1d-glycolipid antigen

(2011) O. Patel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mechanism of regulation of autoimmunity by iNKT cells

(2010) Jan Novak et al.   CYTOKINE

Conventional DCs reduce liver ischemia/reperfusion injury in mice via IL-10 secretion

(2010) Zubin M. Bamboat et al.   JOURNAL OF CLINICAL INVESTIGATION

The Vα14 invariant natural killer T cell TCR forces microbial glycolipids and CD1d into a conserved binding mode

(2010) Yali Li et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Cutting Edge: Crucial Role of IL-1 and IL-23 in the Innate IL-17 Response of Peripheral Lymph Node NK1.1- Invariant NKT Cells to Bacteria

(2010) J.-M. Doisne et al.   JOURNAL OF IMMUNOLOGY

Schistosomal‐Derived Lysophosphatidylcholine Are Involved in Eosinophil Activation and Recruitment through Toll‐Like Receptor–2–Dependent Mechanisms

(2010) Kelly G. Magalhães et al.   JOURNAL OF INFECTIOUS DISEASES

iNKT Cells Control Mouse Spontaneous Carcinoma Independently of Tumor-Specific Cytotoxic T Cells

(2010) Matteo Bellone et al.   PLoS One

Oligoclonality and innate-like features in the TCR repertoire of type II NKT cells reactive to a  -linked self-glycolipid

(2010) P. Arrenberg et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Type I natural killer T cells suppress tumors caused by p53 loss in mice

(2009) J. B. Swann et al.   BLOOD

Multiple tissue-specific isoforms of sulfatide activate CD1d-restricted type II NKT cells

(2009) Maria Blomqvist et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

T Cell Receptor CDR2β and CDR3β Loops Collaborate Functionally to Shape the iNKT Cell Repertoire

(2009) Thierry Mallevaey et al.   IMMUNITY

Differential Recognition of CD1d-α-Galactosyl Ceramide by the Vβ8.2 and Vβ7 Semi-invariant NKT T Cell Receptors

(2009) Daniel G. Pellicci et al.   IMMUNITY

Natural Lipid Ligands Associated with Human CD1d Targeted to Different Subcellular Compartments

(2009) W. Yuan et al.   JOURNAL OF IMMUNOLOGY

Skin and Peripheral Lymph Node Invariant NKT Cells Are Mainly Retinoic Acid Receptor-Related Orphan Receptor  t+ and Respond Preferentially under Inflammatory Conditions

(2009) J.-M. Doisne et al.   JOURNAL OF IMMUNOLOGY

Natural killer T cells and the regulation of asthma

(2009) P Matangkasombut et al.   Mucosal Immunology

Antigen recognition by CD1d-restricted NKT T cell receptors

(2009) Dale I. Godfrey et al.   SEMINARS IN IMMUNOLOGY

How invariant natural killer T cells respond to infection by recognizing microbial or endogenous lipid antigens

(2009) Manfred Brigl et al.   SEMINARS IN IMMUNOLOGY

Recognition of Lyso-Phospholipids by Human Natural Killer T Lymphocytes

(2009) Lisa M. Fox et al.   PLOS BIOLOGY

Inflammation-associated lysophospholipids as ligands for CD1d-restricted T cells in human cancer

(2008) D. H. Chang et al.   BLOOD

Type I NKT cells protect (and type II NKT cells suppress) the host's innate antitumor immune response to a B-cell lymphoma

(2008) G. J. Renukaradhya et al.   BLOOD

CD1d-restricted iNKT cells, the ‘Swiss-Army knife’ of the immune system

(2008) Jennifer L Matsuda et al.   CURRENT OPINION IN IMMUNOLOGY

Peripheral blood progenitor cell product contains Th1-biased noninvariant CD1d-reactive natural killer T cells: Implications for posttransplant survival

(2008) Angela Shaulov et al.   EXPERIMENTAL HEMATOLOGY

A novel subset of mouse NKT cells bearing the IL-17 receptor B responds to IL-25 and contributes to airway hyperreactivity

(2008) Asuka Terashima et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Molecular profiling reveals distinct functional attributes of CD1d-restricted natural killer (NK) T cell subsets

(2008) Julia Rolf et al.   MOLECULAR IMMUNOLOGY

Critical role of ROR- t in a new thymic pathway leading to IL-17-producing invariant NKT cell differentiation

(2008) M.-L. Michel et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diverse cytokine production by NKT cell subsets and identification of an IL-17-producing CD4-NK1.1- NKT cell population

(2008) J. M. Coquet et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Innate Invariant NKT Cells Recognize Mycobacterium tuberculosis–Infected Macrophages, Produce Interferon-γ, and Kill Intracellular Bacteria

(2008) Isabel Sada-Ovalle et al.   PLoS Pathogens