Polyglycerol-based amphiphilic dendrons as potential siRNA carriers for in vivo applications

Peptide Dendrimer/Lipid Hybrid Systems Are Efficient DNA Transfection Reagents: Structure–Activity Relationships Highlight the Role of Charge Distribution Across Dendrimer Generations

(2013) Albert Kwok et al.   ACS Nano

Dendritic and lipid-based carriers for gene/siRNA delivery (a review)

(2013) Fatemeh Sheikhi Mehrabadi et al.   CURRENT OPINION IN SOLID STATE & MATERIALS SCIENCE

Dual-degradable disulfide-containing PEI–Pluronic/DNA polyplexes: transfection efficiency and balancing protection and DNA release

(2013) Lifen Zhang et al.   International Journal of Nanomedicine

Arginine clustering on calix[4]arene macrocycles for improved cell penetration and DNA delivery

(2013) Valentina Bagnacani et al.   Nature Communications

An Amphiphilic Dendrimer for Effective Delivery of Small Interfering RNA and Gene Silencing In Vitro and In Vivo

(2012) Tianzhu Yu et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multivalency as a Chemical Organization and Action Principle

(2012) Carlo Fasting et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Glycine-Terminated Dendritic Amphiphiles for Nonviral Gene Delivery

(2012) Shashwat Malhotra et al.   BIOMACROMOLECULES

Fingerprinting of the TLR4-induced acute inflammatory response

(2012) Markus Bosmann et al.   EXPERIMENTAL AND MOLECULAR PATHOLOGY

Engineering DNA Nanoparticles as Immunomodulatory Reagents that Activate Regulatory T Cells

(2012) L. Huang et al.   JOURNAL OF IMMUNOLOGY

Effects of a PEG additive on the biomolecular interactions of self-assembled dendron nanostructures

(2012) Anna Barnard et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Colloidal Structure and Stability of DNA/Polycations Polyplexes Investigated by Small Angle Scattering

(2011) Sylvain Prévost et al.   BIOMACROMOLECULES

Multifunctional dendritic polymers in nanomedicine: opportunities and challenges

(2011) Jayant Khandare et al.   CHEMICAL SOCIETY REVIEWS

Degradable Self-Assembling Dendrons for Gene Delivery: Experimental and Theoretical Insights into the Barriers to Cellular Uptake

(2011) Anna Barnard et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Nanogyroids Incorporating Multivalent Lipids: Enhanced Membrane Charge Density and Pore Forming Ability for Gene Silencing

(2011) Cecília Leal et al.   LANGMUIR

Controlled Release of DNA From Photoresponsive Hyperbranched Polyglycerols with Oligoamine Shells

(2011) Wiebke Fischer et al.   MACROMOLECULAR BIOSCIENCE

Hydrophobically Modified Dendrons: Developing Structure−Activity Relationships for DNA Binding and Gene Transfection

(2011) Simon P. Jones et al.   MOLECULAR PHARMACEUTICS

Dendrimers as non-viral vectors for siRNA delivery

(2011) Xiaoxuan Liu et al.   NEW JOURNAL OF CHEMISTRY

Stimuli-Sensitive Synthetic Polypeptide-Based Materials for Drug and Gene Delivery

(2011) Chaoliang He et al.   Advanced Healthcare Materials

Dendritic Polyglycerols with Oligoamine Shells Show Low Toxicity and High siRNA Transfection Efficiency in Vitro

(2010) Wiebke Fischer et al.   BIOCONJUGATE CHEMISTRY

Acid-transforming polypeptide micelles for targeted nonviral gene delivery

(2010) Min Suk Shim et al.   BIOMATERIALS

Quantifying the Effect of Surface Ligands on Dendron-DNA Interactions: Insights into Multivalency through a Combined Experimental and Theoretical Approach

(2010) Simon P. Jones et al.   CHEMISTRY-A EUROPEAN JOURNAL

In vivo delivery of small interfering RNA to tumors and their vasculature by novel dendritic nanocarriers

(2010) Paula Ofek et al.   FASEB JOURNAL

A New Family of Nonionic Dendritic Amphiphiles Displaying Unexpected Packing Parameters in Micellar Assemblies

(2010) Britta Trappmann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Imidazole and Dimethyl Aminopropyl-Functionalized Hyperbranched Polymers for Nucleic Acid Transfection

(2010) Oliver Germershaus et al.   MACROMOLECULAR BIOSCIENCE

Synthesis of Linear Polyamines with Different Amine Spacings and their Ability to Form dsDNA/siRNA Complexes Suitable for Transfection

(2010) Wiebke Fischer et al.   MACROMOLECULAR BIOSCIENCE

Less is more – multiscale modelling of self-assembling multivalency and its impact on DNA binding and gene delivery

(2010) Paola Posocco et al.   Chemical Science

Dendritic Polyglycerols for Biomedical Applications

(2009) Marcelo Calderón et al.   ADVANCED MATERIALS

Surface-engineered targeted PPI dendrimer for efficient intracellular and intratumoral siRNA delivery

(2009) Oleh Taratula et al.   JOURNAL OF CONTROLLED RELEASE

Balancing protection and release of DNA: tools to address a bottleneck of non-viral gene delivery

(2009) C. L. Grigsby et al.   Journal of the Royal Society Interface

The promises and pitfalls of RNA-interference-based therapeutics

(2009) Daniela Castanotto et al.   NATURE

Understanding biophysicochemical interactions at the nano–bio interface

(2009) Andre E. Nel et al.   NATURE MATERIALS

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Progress in developing cationic vectors for non-viral systemic gene therapy against cancer

(2008) Marie Morille et al.   BIOMATERIALS

Synergistic effects in gene delivery—a structure–activity approach to the optimisation of hybrid dendritic–lipidic transfection agents

(2008) Simon P. Jones et al.   CHEMICAL COMMUNICATIONS

Nonviral Vectors for Gene Delivery

(2008) Meredith A. Mintzer et al.   CHEMICAL REVIEWS

A Convergent Approach to Biocompatible Polyglycerol “Click” Dendrons for the Synthesis of Modular Core-Shell Architectures and Their Transport Behavior

(2008) Monika Wyszogrodzka et al.   CHEMISTRY-A EUROPEAN JOURNAL

Dendrimers and the Double Helix - From DNA Binding Towards Gene Therapy

(2008) David Smith   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Oligoethylenimine-grafted polypropylenimine dendrimers as degradable and biocompatible synthetic vectors for gene delivery

(2008) Verena Russ et al.   JOURNAL OF CONTROLLED RELEASE

Oxidative stress and pro-inflammatory responses induced by silica nanoparticles in vivo and in vitro

(2008) Eun-Jung Park et al.   TOXICOLOGY LETTERS