Genetics of the Serrated Pathway to Colorectal Cancer

RNF43 is frequently mutated in colorectal and endometrial cancers

(2014) Marios Giannakis et al.   NATURE GENETICS

A Genetic Progression Model of BrafV600E-Induced Intestinal Tumorigenesis Reveals Targets for Therapeutic Intervention

(2013) Roland Rad et al.   CANCER CELL

Germline Mutations in Oncogene-Induced Senescence Pathways Are Associated With Multiple Sessile Serrated Adenomas

(2013) Manish K. Gala et al.   GASTROENTEROLOGY

Microsatellite Instability and BRAF Mutation Testing in Colorectal Cancer Prognostication

(2013) Paul Lochhead et al.   JNCI-Journal of the National Cancer Institute

Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma

(2013) X. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cancer Risks for Relatives of Patients With Serrated Polyposis

(2012) Aung Ko Win et al.   AMERICAN JOURNAL OF GASTROENTEROLOGY

Comprehensive molecular characterization of human colon and rectal cancer

(2012)   NATURE

Cancer Risks for the Relatives of Colorectal Cancer Cases with a Methylated MLH1 Promoter Region: Data from the Colorectal Cancer Family Registry

(2011) A. J. Levine et al.   Cancer Prevention Research

Ink4a/Arf and Oncogene-Induced Senescence Prevent Tumor Progression during Alternative Colorectal Tumorigenesis

(2010) Moritz Bennecke et al.   CANCER CELL

V600EBraf induces gastrointestinal crypt senescence and promotes tumour progression through enhanced CpG methylation ofp16INK4a

(2010) Linda A. S. Carragher et al.   EMBO Molecular Medicine

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and advanced breast cancer: a proof-of-concept trial

(2010) Andrew Tutt et al.   LANCET

Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial

(2010) M William Audeh et al.   LANCET