Targets and Candidate Agents for Type 2 Diabetes Treatment with Computational Bioinformatics Approach

Prostaglandin E2 Receptor, EP3, Is Induced in Diabetic Islets and Negatively Regulates Glucose- and Hormone-Stimulated Insulin Secretion

(2013) M. E. Kimple et al.   DIABETES

Role of Reduced  -Cell Mass Versus Impaired  -Cell Function in the Pathogenesis of Type 2 Diabetes

(2013) J. J. Meier et al.   DIABETES CARE

Anti-diabetic treatment regulates pro-fibrotic TGF-β serum levels in type 2 diabetics

(2013) Stefan Pscherer et al.   Diabetology & Metabolic Syndrome

A Systems Genetics Approach Identifies Genes and Pathways for Type 2 Diabetes in Human Islets

(2012) Jalal Taneera et al.   Cell Metabolism

β-Cell–Specific Gene Repression: A Mechanism to Protect Against Inappropriate or Maladjusted Insulin Secretion?

(2012) Frans Schuit et al.   DIABETES

Molecular signatures database (MSigDB) 3.0

(2011) A. Liberzon et al.   BIOINFORMATICS

L-carnosine inhibits high-glucose-mediated matrix accumulation in human mesangial cells by interfering with TGF-  production and signalling

(2011) H. Koppel et al.   NEPHROLOGY DIALYSIS TRANSPLANTATION

WikiPathways: building research communities on biological pathways

(2011) T. Kelder et al.   NUCLEIC ACIDS RESEARCH

Inhibition of Stat3 activation by sanguinarine suppresses prostate cancer cell growth and invasion

(2011) Meng Sun et al.   PROSTATE

Sanguinarine induces apoptosis of human osteosarcoma cells through the extrinsic and intrinsic pathways

(2010) Hyunjin Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

WebGestalt2: an updated and expanded version of the Web-based Gene Set Analysis Toolkit

(2010) Dexter Duncan et al.   BMC BIOINFORMATICS

From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus

(2009) R. A. DeFronzo   DIABETES

The role of proteases in transforming growth factor-β activation

(2008) G JENKINS   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Sanguinarine induces apoptosis in A549 human lung cancer cells primarily via cellular glutathione depletion

(2008) Byeong-Churl Jang et al.   TOXICOLOGY IN VITRO

Arachidonic-acid-derived eicosanoids: roles in biology and immunopathology

(2008) Hedi Harizi et al.   TRENDS IN MOLECULAR MEDICINE