Endoplasmic Reticulum Is at the Crossroads of Autophagy, Inflammation, and Apoptosis Signaling Pathways and Participates in the Pathogenesis of Diabetes Mellitus

The role of autophagy in endoplasmic reticulum stress-induced pancreatic β cell death

(2012) Jia-Jing Yin et al.   Autophagy

Sequestosome 1/p62: across diseases

(2012) Thangiah Geetha et al.   BIOMARKERS

Sirtuins and renal diseases: relationship with aging and diabetic nephropathy

(2012) Munehiro Kitada et al.   CLINICAL SCIENCE

ER Stress as a Trigger for  -Cell Dysfunction and Autoimmunity in Type 1 Diabetes

(2012) B. O'Sullivan-Murphy et al.   DIABETES

Adipocytes Secrete Leukotrienes: Contribution to Obesity-Associated Inflammation and Insulin Resistance in Mice

(2012) I. Mothe-Satney et al.   DIABETES

The Role of Endoplasmic Reticulum Stress in Autoimmune-Mediated Beta-Cell Destruction in Type 1 Diabetes

(2012) Jixin Zhong et al.   Experimental Diabetes Research

The Role of Glucosamine-Induced ER Stress in Diabetic Atherogenesis

(2012) Daniel R. Beriault et al.   Experimental Diabetes Research

Endothelial Dysfunction in Diabetes Mellitus: Possible Involvement of Endoplasmic Reticulum Stress?

(2012) Basma Basha et al.   Experimental Diabetes Research

Transient Aggregation of Ubiquitinated Proteins Is a Cytosolic Unfolded Protein Response to Inflammation and Endoplasmic Reticulum Stress

(2012) Xian-De Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Diabetes

(2012) Herb Brody   NATURE

Post-prandial glucose and diabetic complications: systematic review of observational studies

(2011) Edoardo Mannucci et al.   ACTA DIABETOLOGICA

Autophagy as a Therapeutic Target in Diabetic Nephropathy

(2011) Yuki Tanaka et al.   Experimental Diabetes Research

ER Stress and Apoptosis: A New Mechanism for Retinal Cell Death

(2011) Guangjun Jing et al.   Experimental Diabetes Research

Inflammatory molecules and pathways in the pathogenesis of diabetic nephropathy

(2011) Juan F. Navarro-González et al.   Nature Reviews Nephrology

The unfolded protein response controls induction and activation of ADAM17/TACE by severe hypoxia and ER stress

(2011) T Rzymski et al.   ONCOGENE

Road to Ruin: Targeting Proteins for Degradation in the Endoplasmic Reticulum

(2011) M. H. Smith et al.   SCIENCE

Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease

(2010) Gökhan S. Hotamisligil   CELL

Autophagy in liver diseases

(2010) Pierre-Emmanuel Rautou et al.   JOURNAL OF HEPATOLOGY

Autophagy and the Integrated Stress Response

(2010) Guido Kroemer et al.   MOLECULAR CELL

Endoplasmic reticulum stress inhibition protects steatotic and non-steatotic livers in partial hepatectomy under ischemia–reperfusion

(2010) I Ben Mosbah et al.   Cell Death & Disease

IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates

(2009) Dan Han et al.   CELL

Translation Attenuation through eIF2α Phosphorylation Prevents Oxidative Stress and Maintains the Differentiated State in β Cells

(2009) Sung Hoon Back et al.   Cell Metabolism

AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome

(2009) Bei B. Zhang et al.   Cell Metabolism

The α-glucosidase inhibitor acarbose prevents obesity and simple steatosis in sequestosome 1/A170/p62 deficient mice

(2009) Kosuke Okada et al.   HEPATOLOGY RESEARCH

How Punctual Ablation of Regulatory T Cells Unleashes an Autoimmune Lesion within the Pancreatic Islets

(2009) Markus Feuerer et al.   IMMUNITY

GRP78 expression inhibits insulin and ER stress–induced SREBP-1c activation and reduces hepatic steatosis in mice

(2009) Hélène L. Kammoun et al.   JOURNAL OF CLINICAL INVESTIGATION

Adipocytes as Immune Cells: Differential Expression of TWEAK, BAFF, and APRIL and Their Receptors (Fn14, BAFF-R, TACI, and BCMA) at Different Stages of Normal and Pathological Adipose Tissue Development

(2009) V.-I. Alexaki et al.   JOURNAL OF IMMUNOLOGY

Activation of the Akt-NF- B Pathway by Subtilase Cytotoxin through the ATF6 Branch of the Unfolded Protein Response

(2009) H. Yamazaki et al.   JOURNAL OF IMMUNOLOGY

Discovery of Atg5/Atg7-independent alternative macroautophagy

(2009) Yuya Nishida et al.   NATURE

XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease

(2008) Arthur Kaser et al.   CELL

Loss of Autophagy Diminishes Pancreatic β Cell Mass and Function with Resultant Hyperglycemia

(2008) Hye Seung Jung et al.   Cell Metabolism

Autophagy Is Important in Islet Homeostasis and Compensatory Increase of Beta Cell Mass in Response to High-Fat Diet

(2008) Chie Ebato et al.   Cell Metabolism

Inhibition of apolipoprotein B100 secretion by lipid-induced hepatic endoplasmic reticulum stress in rodents

(2008) Tsuguhito Ota et al.   JOURNAL OF CLINICAL INVESTIGATION

Autophagy fights disease through cellular self-digestion

(2008) Noboru Mizushima et al.   NATURE

A Predominant Role for Parenchymal c-Jun Amino Terminal Kinase (JNK) in the Regulation of Systemic Insulin Sensitivity

(2008) Sara N. Vallerie et al.   PLoS One