Making Sense in Antisense: Therapeutic Potential of Noncoding RNAs in Diabetes-Induced Vascular Dysfunction

MicroRNAs in Metabolic Disease

(2013) Carlos Fernández-Hernando et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MicroRNAs and Metabolism Crosstalk in Energy Homeostasis

(2013) Olivier Dumortier et al.   Cell Metabolism

Endothelial Microparticle–Mediated Transfer of MicroRNA-126 Promotes Vascular Endothelial Cell Repair via SPRED1 and Is Abrogated in Glucose-Damaged Endothelial Microparticles

(2013) Felix Jansen et al.   CIRCULATION

Induction of Vascular Insulin Resistance and Endothelin-1 Expression and Acceleration of Atherosclerosis by the Overexpression of Protein Kinase C-β Isoform in the Endothelium

(2013) Qian Li et al.   CIRCULATION RESEARCH

Novel Long Noncoding RNAs Are Regulated by Angiotensin II in Vascular Smooth Muscle Cells

(2013) Amy Leung et al.   CIRCULATION RESEARCH

Mineralocorticoid Receptor-Mediated Vascular Insulin Resistance: An Early Contributor to Diabetes-Related Vascular Disease?

(2013) S. B. Bender et al.   DIABETES

Human adipose microRNA-221 is upregulated in obesity and affects fat metabolism downstream of leptin and TNF-α

(2013) A. Meerson et al.   DIABETOLOGIA

Identification of particular groups of microRNAs that positively or negatively impact on beta cell function in obese models of type 2 diabetes

(2013) Valeria Nesca et al.   DIABETOLOGIA

Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I

(2013) Francesco Paneni et al.   EUROPEAN HEART JOURNAL

S100P/RAGE signaling regulates microRNA-155 expression via AP-1 activation in colon cancer

(2013) Benjamin Chidi Onyeagucha et al.   EXPERIMENTAL CELL RESEARCH

Methods of accelerated atherosclerosis in diabetic patients

(2013) Gerard Pasterkamp   HEART

Free leptin, carotid plaque phenotype and relevance to related symptomatology: Insights from the OPAL-Lille carotid endarterectomy study

(2013) Ahmed Elkalioubie et al.   INTERNATIONAL JOURNAL OF CARDIOLOGY

Oxidative Stress and MicroRNAs in Vascular Diseases

(2013) Alessandra Magenta et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Adipocytokines in relation to cardiovascular disease

(2013) Johan Van de Voorde et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

MicroRNA-106b induces mitochondrial dysfunction and insulin resistance in C2C12 myotubes by targeting mitofusin-2

(2013) Ying Zhang et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Obesity-induced overexpression of miR-802 impairs glucose metabolism through silencing of Hnf1b

(2013) Jan-Wilhelm Kornfeld et al.   NATURE

Targeting long non-coding RNA to therapeutically upregulate gene expression

(2013) Claes Wahlestedt   NATURE REVIEWS DRUG DISCOVERY

Treatment of HCV Infection by Targeting MicroRNA

(2013) Harry L.A. Janssen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Increased MicroRNA-146a Levels in Plasma of Patients with Newly Diagnosed Type 2 Diabetes Mellitus

(2013) Ying Rong et al.   PLoS One

Alu Elements in ANRIL Non-Coding RNA at Chromosome 9p21 Modulate Atherogenic Cell Functions through Trans-Regulation of Gene Networks

(2013) Lesca M. Holdt et al.   PLoS Genetics

Genome Regulation by Long Noncoding RNAs

(2012) John L. Rinn et al.   Annual Review of Biochemistry

Apolipoprotein B-48 as a determinant of endothelial function in obese subjects with type 2 diabetes mellitus: Effect of fenofibrate treatment

(2012) Dick C. Chan et al.   ATHEROSCLEROSIS

Adipokines and the cardiovascular system: mechanisms mediating health and disease

(2012) Josette M. Northcott et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

Dual role of lipoproteins in endothelial cell dysfunction in atherosclerosis

(2012) Camelia S. Stancu et al.   CELL AND TISSUE RESEARCH

Human β Cell Transcriptome Analysis Uncovers lncRNAs That Are Tissue-Specific, Dynamically Regulated, and Abnormally Expressed in Type 2 Diabetes

(2012) Ignasi Morán et al.   Cell Metabolism

MicroRNAs in Vascular and Metabolic Disease

(2012) Anna Zampetaki et al.   CIRCULATION RESEARCH

Physiological, pathological and potential therapeutic roles of adipokines

(2012) Inês Falcão-Pires et al.   DRUG DISCOVERY TODAY

Vascular Disease in Diabetic Women: Why Do They Miss the Female Protection?

(2012) Ana Paula Villela Dantas et al.   Experimental Diabetes Research

Landscape of transcription in human cells

(2012) Sarah Djebali et al.   NATURE

Atheroprotective communication between endothelial cells and smooth muscle cells through miRNAs

(2012) Eduard Hergenreider et al.   NATURE CELL BIOLOGY

Platelet microRNAs: From platelet biology to possible disease biomarkers and therapeutic targets

(2012) Dimitrios A. Stakos et al.   PLATELETS

Control of mitochondrial metabolism and systemic energy homeostasis by microRNAs 378 and 378

(2012) M. Carrer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-21 Blocks Abdominal Aortic Aneurysm Development and Nicotine-Augmented Expansion

(2012) L. Maegdefessel et al.   Science Translational Medicine

Diabetic Vascular Disease: Characteristics of Vascular Disease Unique to the Diabetic Patient

(2012) Gary W. Gibbons et al.   Seminars in Vascular Surgery

Atheroprotective mechanisms of shear stress-regulated microRNAs

(2012) Reinier A. Boon et al.   THROMBOSIS AND HAEMOSTASIS

Role of oxidative stress in diabetes-mediated vascular dysfunction: Unifying hypothesis of diabetes revisited

(2012) Stephen W. Schaffer et al.   VASCULAR PHARMACOLOGY

Resistin: functional roles and therapeutic considerations for cardiovascular disease

(2011) Md S Jamaluddin et al.   BRITISH JOURNAL OF PHARMACOLOGY

The Lin28/let-7 Axis Regulates Glucose Metabolism

(2011) Hao Zhu et al.   CELL

Deregulation of microRNA-503 Contributes to Diabetes Mellitus–Induced Impairment of Endothelial Function and Reparative Angiogenesis After Limb Ischemia

(2011) Andrea Caporali et al.   CIRCULATION

MicroRNA-24 Regulates Vascularity After Myocardial Infarction

(2011) Jan Fiedler et al.   CIRCULATION

MicroRNA-133 Controls Vascular Smooth Muscle Cell Phenotypic Switch In Vitro and Vascular Remodeling In Vivo

(2011) Daniele Torella et al.   CIRCULATION RESEARCH

RETRACTED ARTICLE: MIR221/MIR222-driven post-transcriptional regulation of P27KIP1 and P57KIP2 is crucial for high-glucose- and AGE-mediated vascular cell damage

(2011) G. Togliatto et al.   DIABETOLOGIA

miRNAs control insulin content in pancreatic β-cells via downregulation of transcriptional repressors

(2011) Tal Melkman-Zehavi et al.   EMBO JOURNAL

Nitric oxide synthases: regulation and function

(2011) U. Forstermann et al.   EUROPEAN HEART JOURNAL

MicroRNAs regulating oxidative stress and inflammation in relation to obesity and atherosclerosis

(2011) Maarten Hulsmans et al.   FASEB JOURNAL

miR-210: More than a silent player in hypoxia

(2011) Cecilia Devlin et al.   IUBMB LIFE

miR-200a Regulates SIRT1 Expression and Epithelial to Mesenchymal Transition (EMT)-like Transformation in Mammary Epithelial Cells

(2011) Gabriel Eades et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of MicroRNA-214-Targeting Phosphatase and Tensin Homolog in Advanced Glycation End Product-Induced Apoptosis Delay in Monocytes

(2011) L.-M. Li et al.   JOURNAL OF IMMUNOLOGY

Inhibition of miR-33a/b in non-human primates raises plasma HDL and lowers VLDL triglycerides

(2011) Katey J. Rayner et al.   NATURE

MicroRNA-21 targets peroxisome proliferators-activated receptor-  in an autoregulatory loop to modulate flow-induced endothelial inflammation

(2011) J. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Control of glucose homeostasis and insulin sensitivity by the Let-7 family of microRNAs

(2011) R. J. A. Frost et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

microRNA-222 Controls Neovascularization by Regulating Signal Transducer and Activator of Transcription 5A Expression

(2010) Patrizia Dentelli et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

The Many Faces of Endothelial Microparticles

(2010) Françoise Dignat-George et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

MicroRNA-210 as a Novel Therapy for Treatment of Ischemic Heart Disease

(2010) S. Hu et al.   CIRCULATION

Microparticles

(2010) Sebastian F. Mause et al.   CIRCULATION RESEARCH

Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes

(2010) Anna Zampetaki et al.   CIRCULATION RESEARCH

Fenofibrate improves endothelial function in the brachial artery and forearm resistance arterioles of statin-treated Type 2 diabetic patients

(2010) Sandra J. Hamilton et al.   CLINICAL SCIENCE

Involvement of MicroRNAs in the Cytotoxic Effects Exerted by Proinflammatory Cytokines on Pancreatic  -Cells

(2010) E. Roggli et al.   DIABETES

ANRIL, a long, noncoding RNA, is an unexpected major hotspot in GWAS

(2010) Eric Pasmant et al.   FASEB JOURNAL

Vascular Oxidative Stress: The Common Link in Hypertensive and Diabetic Vascular Disease

(2010) Richard A Cohen et al.   JOURNAL OF CARDIOVASCULAR PHARMACOLOGY

MicroRNA-370 controls the expression of MicroRNA-122 and Cpt1α and affects lipid metabolism

(2010) Dimitrios Iliopoulos et al.   JOURNAL OF LIPID RESEARCH

Integration of microRNA changes in vivo identifies novel molecular features of muscle insulin resistance in type 2 diabetes

(2010) Iain J Gallagher et al.   Genome Medicine

MicroRNAs: Target Recognition and Regulatory Functions

(2009) David P. Bartel   CELL

MicroRNA 217 Modulates Endothelial Cell Senescence via Silent Information Regulator 1

(2009) Rossella Menghini et al.   CIRCULATION

Downregulation of MiR-199a Derepresses Hypoxia-Inducible Factor-1α and Sirtuin 1 and Recapitulates Hypoxia Preconditioning in Cardiac Myocytes

(2009) Shweta Rane et al.   CIRCULATION RESEARCH

A Necessary Role of miR-221 and miR-222 in Vascular Smooth Muscle Cell Proliferation and Neointimal Hyperplasia

(2009) Xiaojun Liu et al.   CIRCULATION RESEARCH

The microRNA Signature in Response to Insulin Reveals Its Implication in the Transcriptional Action of Insulin in Human Skeletal Muscle and the Role of a Sterol Regulatory Element-Binding Protein-1c/Myocyte Enhancer Factor 2C Pathway

(2009) A. Granjon et al.   DIABETES

Synergistic effects of telmisartan and simvastatin on endothelial progenitor cells

(2009) Martin Steinmetz et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Obesity and genetics regulate microRNAs in islets, liver, and adipose of diabetic mice

(2009) Enpeng Zhao et al.   MAMMALIAN GENOME

Dyslipidemia in type 2 diabetes mellitus

(2009) Arshag D Mooradian   Nature Reviews Endocrinology

MicroRNA Expression in Human Omental and Subcutaneous Adipose Tissue

(2009) Nora Klöting et al.   PLoS One

MicroRNA-92a Controls Angiogenesis and Functional Recovery of Ischemic Tissues in Mice

(2009) A. Bonauer et al.   SCIENCE

Most mammalian mRNAs are conserved targets of microRNAs

(2008) R. C. Friedman et al.   GENOME RESEARCH

Adiponectin Blocks Interleukin-18-mediated Endothelial Cell Death via APPL1-dependent AMP-activated Protein Kinase (AMPK) Activation and IKK/NF-κB/PTEN Suppression

(2008) Bysani Chandrasekar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Induction of MicroRNA-221 by Platelet-derived Growth Factor Signaling Is Critical for Modulation of Vascular Smooth Muscle Phenotype

(2008) Brandi N. Davis et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SMAD proteins control DROSHA-mediated microRNA maturation

(2008) Brandi N. Davis et al.   NATURE

Diabetes-Related Microvascular and Macrovascular Diseases in the Physical Therapy Setting

(2008) W Todd Cade   PHYSICAL THERAPY

miR-34a repression of SIRT1 regulates apoptosis

(2008) M. Yamakuchi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of glucose-regulated miRNAs from pancreatic   cells reveals a role for miR-30d in insulin transcription

(2008) X. Tang et al.   RNA