DNA binding polarity, dimerization, and ATPase ring remodeling in the CMG helicase of the eukaryotic replisome

Prereplicative complexes assembled in vitro support origin-dependent and independent DNA replication

(2014) K. F. On et al.   EMBO JOURNAL

Dynamic look at DNA unwinding by a replicative helicase

(2014) Seung-Jae Lee et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A conserved MCM single-stranded DNA binding element is essential for replication initiation

(2014) Clifford A Froelich et al.   eLife

Reconstitution of the 26S proteasome reveals functional asymmetries in its AAA+ unfoldase

(2013) Robyn Beckwith et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-EM structure of a helicase loading intermediate containing ORC–Cdc6–Cdt1–MCM2-7 bound to DNA

(2013) Jingchuan Sun et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

DNA binding properties of human Cdc45 suggest a function as molecular wedge for DNA unwinding

(2013) Anna Szambowska et al.   NUCLEIC ACIDS RESEARCH

Unveiling the Long-Held Secrets of the 26S Proteasome

(2013) Friedrich Förster et al.   STRUCTURE

Comparison of Segger and other methods for segmentation and rigid-body docking of molecular components in Cryo-EM density maps

(2012) Grigore Pintilie et al.   BIOPOLYMERS

The Hexameric Helicase DnaB Adopts a Nonplanar Conformation during Translocation

(2012) Ornchuma Itsathitphaisarn et al.   CELL

Activation of the replicative DNA helicase: breaking up is hard to do

(2012) Dominik Boos et al.   CURRENT OPINION IN CELL BIOLOGY

RELION: Implementation of a Bayesian approach to cryo-EM structure determination

(2012) Sjors H.W. Scheres   JOURNAL OF STRUCTURAL BIOLOGY

Complete subunit architecture of the proteasome regulatory particle

(2012) Gabriel C. Lander et al.   NATURE

ATP-dependent conformational dynamics underlie the functional asymmetry of the replicative helicase from a minimalist eukaryote

(2012) Artem Y. Lyubimov et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cdc45: the missing RecJ ortholog in eukaryotes?

(2011) Luis Sanchez-Pulido et al.   BIOINFORMATICS

Architectures of archaeal GINS complexes, essential DNA replication initiation factors

(2011) Takuji Oyama et al.   BMC BIOLOGY

Selective Bypass of a Lagging Strand Roadblock by the Eukaryotic Replicative DNA Helicase

(2011) Yu V. Fu et al.   CELL

The nuts and bolts of ring-translocase structure and mechanism

(2011) Artem Y Lyubimov et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Electron microscopy visualization of DNA–protein complexes formed by Ku and DNA ligase IV

(2011) Patricia Grob et al.   DNA REPAIR

Structural and Functional Insights into the DNA Replication Factor Cdc45 Reveal an Evolutionary Relationship to the DHH Family of Phosphoesterases

(2011) Ivet Krastanova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structural basis for MCM2–7 helicase activation by GINS and Cdc45

(2011) Alessandro Costa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

CDK-dependent complex formation between replication proteins Dpb11, Sld2, Pol  , and GINS in budding yeast

(2010) S. Muramatsu et al.   GENES & DEVELOPMENT

How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?

(2010) K. Labib   GENES & DEVELOPMENT

Uncoupling of Sister Replisomes during Eukaryotic DNA Replication

(2010) Hasan Yardimci et al.   MOLECULAR CELL

Activation of the MCM2-7 Helicase by Association with Cdc45 and GINS Proteins

(2010) Ivar Ilves et al.   MOLECULAR CELL

The Dbf4–Cdc7 kinase promotes S phase by alleviating an inhibitory activity in Mcm4

(2010) Yi-Jun Sheu et al.   NATURE

Concerted Loading of Mcm2–7 Double Hexamers around DNA during DNA Replication Origin Licensing

(2009) Dirk Remus et al.   CELL

A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase α within the eukaryotic replisome

(2009) Agnieszka Gambus et al.   EMBO JOURNAL

A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

(2009) C. Evrin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

On helicases and other motor proteins

(2008) Eric J Enemark et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

JADAS: A customizable automated data acquisition system and its application to ice-embedded single particles

(2008) J ZHANG et al.   JOURNAL OF STRUCTURAL BIOLOGY

Subunit Organization of Mcm2-7 and the Unequal Role of Active Sites in ATP Hydrolysis and Viability

(2008) M. L. Bochman et al.   MOLECULAR AND CELLULAR BIOLOGY

The Mcm2-7 Complex Has In Vitro Helicase Activity

(2008) Matthew L. Bochman et al.   MOLECULAR CELL