- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting Huntington’s disease through histone deacetylases
Authors
Keywords
-
Journal
Clinical Epigenetics
Volume 2, Issue 2, Pages 257-277
Publisher
Springer Nature
Online
2011-02-18
DOI
10.1007/s13148-011-0025-7
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A stress sensitive ER membrane-association domain in Huntingtin protein defines a potential role for Huntingtin in the regulation of autophagy
- (2014) Randy Singh Atwal et al. Autophagy
- HspB8 and Bag3: A new chaperone complex targeting misfolded proteins to macroautophagy
- (2014) Serena Carra et al. Autophagy
- Converging Pathways in the Occurrence of Endoplasmic Reticulum (ER) Stress in Huntingtons Disease
- (2011) R. Vidal et al. CURRENT MOLECULAR MEDICINE
- Localization of sequence variations in PGC-1α influence their modifying effect in Huntington disease
- (2011) Hong Van B Che et al. Molecular Neurodegeneration
- Identification of phenylbutyrate-generated metabolites in Huntington disease patients using parallel liquid chromatography/electrochemical array/mass spectrometry and off-line tandem mass spectrometry
- (2010) Erika N. Ebbel et al. ANALYTICAL BIOCHEMISTRY
- microRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity
- (2010) J Zhang et al. BRITISH JOURNAL OF CANCER
- Immunity, Inflammation, and Cancer
- (2010) Sergei I. Grivennikov et al. CELL
- HDAC6 a new cellular stress surveillance factor
- (2010) Patrick Matthias et al. CELL CYCLE
- HDAC inhibition promotes neuronal outgrowth and counteracts growth cone collapse through CBP/p300 and P/CAF-dependent p53 acetylation
- (2010) P Gaub et al. CELL DEATH AND DIFFERENTIATION
- The Role of Histone Deacetylase Inhibitors in the Treatment of Patients With Cutaneous T-Cell Lymphoma
- (2010) Kenneth B. Hymes Clinical Lymphoma Myeloma & Leukemia
- Altered microRNA regulation in Huntington's disease models
- (2010) Soon-Tae Lee et al. EXPERIMENTAL NEUROLOGY
- Alternative Splicing of the Histone Demethylase LSD1/KDM1 Contributes to the Modulation of Neurite Morphogenesis in the Mammalian Nervous System
- (2010) C. Zibetti et al. JOURNAL OF NEUROSCIENCE
- Human accelerated region 1 noncoding RNA is repressed by REST in Huntington's disease
- (2010) Rory Johnson et al. PHYSIOLOGICAL GENOMICS
- Huntingtin Interacts with the Cue Domain of gp78 and Inhibits gp78 Binding to Ubiquitin and p97/VCP
- (2010) Hui Yang et al. PLoS One
- Slowed progression in models of huntington disease by adipose stem cell transplantation
- (2009) Soon-Tae Lee et al. ANNALS OF NEUROLOGY
- Transcriptional dysregulation of coding and non-coding genes in cellular models of Huntington's disease
- (2009) Angela Bithell et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Inflammation in transgenic mouse models of neurodegenerative disorders
- (2009) Claudia Schwab et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death
- (2009) Kaoru Saijo et al. CELL
- Acetylation Targets Mutant Huntingtin to Autophagosomes for Degradation
- (2009) Hyunkyung Jeong et al. CELL
- Phosphoproteomic Analysis of Human Embryonic Stem Cells
- (2009) Laurence M. Brill et al. Cell Stem Cell
- Impaired PGC-1α function in muscle in Huntington's disease
- (2009) Rajnish K. Chaturvedi et al. HUMAN MOLECULAR GENETICS
- Huntingtin facilitates polycomb repressive complex 2
- (2009) Ihn Sik Seong et al. HUMAN MOLECULAR GENETICS
- Mechanisms of transcriptional repression by histone lysine methylation
- (2009) Philip Hublitz et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY
- SCAMP5 Links Endoplasmic Reticulum Stress to the Accumulation of Expanded Polyglutamine Protein Aggregates via Endocytosis Inhibition
- (2009) Jee-Yeon Noh et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Heterogeneous Nuclear Ribonucleoprotein L Is a Subunit of Human KMT3a/Set2 Complex Required for H3 Lys-36 Trimethylation Activityin Vivo
- (2009) Wen Yuan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Rrs1 Is Involved in Endoplasmic Reticulum Stress Response in Huntington Disease
- (2009) Alisia Carnemolla et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Phosphorylation of Threonine 3
- (2009) Charity T. Aiken et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- IKK phosphorylates Huntingtin and targets it for degradation by the proteasome and lysosome
- (2009) Leslie Michels Thompson et al. JOURNAL OF CELL BIOLOGY
- NF-κB regulation: the nuclear response
- (2009) Arun K. Mankan et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Oxidative stress induced lung cancer and COPD: opportunities for epigenetic therapy
- (2009) Matthew W. Lawless et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Tau - an inhibitor of deacetylase HDAC6 function
- (2009) Mar Perez et al. JOURNAL OF NEUROCHEMISTRY
- The Bifunctional microRNA miR-9/miR-9* Regulates REST and CoREST and Is Downregulated in Huntington's Disease
- (2009) A. N. Packer et al. JOURNAL OF NEUROSCIENCE
- SysPTM: A Systematic Resource for Proteomic Research on Post-translational Modifications
- (2009) Hong Li et al. MOLECULAR & CELLULAR PROTEOMICS
- The gene coding for PGC-1α modifies age at onset in Huntington's Disease
- (2009) Patrick Weydt et al. Molecular Neurodegeneration
- PGC-1alpha as modifier of onset age in Huntington disease
- (2009) Elahe Taherzadeh-Fard et al. Molecular Neurodegeneration
- Serines 13 and 16 Are Critical Determinants of Full-Length Human Mutant Huntingtin Induced Disease Pathogenesis in HD Mice
- (2009) Xiaofeng Gu et al. NEURON
- Valproate ameliorates the survival and the motor performance in a transgenic mouse model of Huntington's disease
- (2009) Dénes Zádori et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Genetic Knock-Down of HDAC7 Does Not Ameliorate Disease Pathogenesis in the R6/2 Mouse Model of Huntington's Disease
- (2009) Caroline L. Benn et al. PLoS One
- IKKα and IKKβ Regulation of DNA Damage-Induced Cleavage of Huntingtin
- (2009) Ali Khoshnan et al. PLoS One
- Differential Deployment of REST and CoREST Promotes Glial Subtype Specification and Oligodendrocyte Lineage Maturation
- (2009) Joseph J. Abrajano et al. PLoS One
- REST and CoREST Modulate Neuronal Subtype Specification, Maturation and Maintenance
- (2009) Joseph J. Abrajano et al. PLoS One
- Accumulation of ubiquitin conjugates in a polyglutamine disease model occurs without global ubiquitin/proteasome system impairment
- (2009) C. J. Maynard et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Histone deacetylases 1 and 2 control the progression of neural precursors to neurons during brain development
- (2009) R. L. Montgomery et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rhes, a Striatal Specific Protein, Mediates Mutant-Huntingtin Cytotoxicity
- (2009) S. Subramaniam et al. SCIENCE
- Histone methyltransferases in cancer
- (2009) Mareike Albert et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Targeting Histone Deacetylases for the Treatment of Immune, Endocrine & Metabolic Disorders
- (2009) M. Lawless et al. Endocrine Metabolic & Immune Disorders-Drug Targets
- Determination of the class and isoform selectivity of small-molecule histone deacetylase inhibitors
- (2008) Nagma Khan et al. BIOCHEMICAL JOURNAL
- Histone deacetylases 1 and 2 are expressed at distinct stages of neuro-glial development
- (2008) Jessica L. MacDonald et al. DEVELOPMENTAL DYNAMICS
- Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons
- (2008) Emilie Colin et al. EMBO JOURNAL
- Inhibition of endoplasmic reticulum stress counteracts neuronal cell death and protein aggregation caused by N-terminal mutant huntingtin proteins
- (2008) Sami Reijonen et al. EXPERIMENTAL CELL RESEARCH
- Role of the repressor JDP2 in the amino acid-regulated transcription ofCHOP
- (2008) Yoan Chérasse et al. FEBS LETTERS
- Monoallele deletion of CBP leads to pericentromeric heterochromatin condensation through ESET expression and histone H3 (K9) methylation
- (2008) Junghee Lee et al. HUMAN MOLECULAR GENETICS
- Phosphorylation of mutant huntingtin at S421 restores anterograde and retrograde transport in neurons
- (2008) Diana Zala et al. HUMAN MOLECULAR GENETICS
- Cell cycle activation in striatal neurons from Huntington's disease patients and rats treated with 3-nitropropionic acid
- (2008) Carme Pelegrí et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- HspB8 Participates in Protein Quality Control by a Non-chaperone-like Mechanism That Requires eIF2α Phosphorylation
- (2008) Serena Carra et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Impaired ubiquitin–proteasome system activity in the synapses of Huntington's disease mice
- (2008) Jianjun Wang et al. JOURNAL OF CELL BIOLOGY
- Targeting histone deacetylases for the treatment of disease
- (2008) M. W. Lawless et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Altered Histone Monoubiquitylation Mediated by Mutant Huntingtin Induces Transcriptional Dysregulation
- (2008) M.-O. Kim et al. JOURNAL OF NEUROSCIENCE
- Direct Binding with Histone Deacetylase 6 Mediates the Reversible Recruitment of Parkin to the Centrosome
- (2008) Q. Jiang et al. JOURNAL OF NEUROSCIENCE
- Phosphoproteomic Analysis of Human Brain by Calcium Phosphate Precipitation and Mass Spectrometry
- (2008) Qiangwei Xia et al. JOURNAL OF PROTEOME RESEARCH
- Expanded CAG repeats in the murine Huntington's disease gene increases neuronal differentiation of embryonic and neural stem cells
- (2008) Matthew T. Lorincz et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Phosphorylation of huntingtin reduces the accumulation of its nuclear fragments
- (2008) Simon C. Warby et al. MOLECULAR AND CELLULAR NEUROSCIENCE
- Kinase-Selective Enrichment Enables Quantitative Phosphoproteomics of the Kinome across the Cell Cycle
- (2008) Henrik Daub et al. MOLECULAR CELL
- Pisa syndrome and Parkinsonism secondary to valproic acid in Huntington's disease
- (2008) Zulema Salazar et al. MOVEMENT DISORDERS
- Sirt1 contributes critically to the redox-dependent fate of neural progenitors
- (2008) Timour Prozorovski et al. NATURE CELL BIOLOGY
- Is there a code embedded in proteins that is based on post-translational modifications?
- (2008) Robert J. Sims et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- One step at a time: endoplasmic reticulum-associated degradation
- (2008) Shruthi S. Vembar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Valproic acid promotes neuronal differentiation by induction of proneural factors in association with H4 acetylation
- (2008) In Tag Yu et al. NEUROPHARMACOLOGY
- Inaugural Huntington Disease Clinical Research Symposium Organized by the Huntington Study Group
- (2008) Katharine Moser et al. Neurotherapeutics
- The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice
- (2008) E. A. Thomas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A quantitative atlas of mitotic phosphorylation
- (2008) N. Dephoure et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A pervasive role of histone acetyltransferases and deacetylases in an NF-κB-signaling code
- (2008) Miriam Calao et al. TRENDS IN BIOCHEMICAL SCIENCES
- Complementary roles for histone deacetylases 1, 2, and 3 in differentiation of pluripotent stem cells
- (2007) Glen W. Humphrey et al. DIFFERENTIATION
- Mitogen- and stress-activated protein kinase-1 deficiency is involved in expanded-huntingtin-induced transcriptional dysregulation and striatal death
- (2007) Emmanuel Roze et al. FASEB JOURNAL
- Developmental expression of histone deacetylase 11 in the murine brain
- (2007) Hedi Liu et al. JOURNAL OF NEUROSCIENCE RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now