Small Molecule Inhibitor of Type Three Secretion System Belonging to a Class 2,4-disubstituted-4H-[1,3,4]-thiadiazine-5-ones Improves Survival and Decreases Bacterial Loads in an Airway Pseudomonas aeruginosa Infection in Mice

T3SS effector ExoY reduces inflammasome-related responses by suppressing bacterial motility and delaying activation of NF-κB and caspase-1

(2017) Jisu Jeon et al.   FEBS Journal

The human NAIP-NLRC4-inflammasome senses the Pseudomonas aeruginosa T3SS inner-rod protein

(2017) Teddy Grandjean et al.   INTERNATIONAL IMMUNOLOGY

Understanding the acute inflammatory response to Pseudomonas aeruginosa infection: differences between susceptible and multidrug-resistant strains in a mouse peritonitis model

(2017) Silvia Gómez-Zorrilla et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Bispecific antibody targets multiple Pseudomonas aeruginosa evasion mechanisms in the lung vasculature

(2017) Ajitha Thanabalasuriar et al.   JOURNAL OF CLINICAL INVESTIGATION

Host and Pathogen Biomarkers for Severe Pseudomonas aeruginosa Infections

(2017) Carlos Juan et al.   JOURNAL OF INFECTIOUS DISEASES

Multidrug-resistant Enterobacteriaceae, Pseudomonas aeruginosa , and vancomycin-resistant Enterococcus : Three major threats to hematopoietic stem cell transplant recipients

(2017) Michael J. Satlin et al.   Transplant Infectious Disease

A small-molecule compound belonging to a class of 2,4-disubstituted 1,3,4-thiadiazine-5-ones suppresses Salmonella infection in vivo

(2016) Ludmila N Nesterenko et al.   JOURNAL OF ANTIBIOTICS

High Throughput Combinatorial Formatting of PcrV Nanobodies for Efficient Potency Improvement

(2016) Evelyn De Tavernier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A small-molecule compound belonging to a class of 2,4-disubstituted 1,3,4-thiadiazine-5-ones inhibits intracellular growth and persistence of Chlamydia trachomatis

(2016) Naylia A. Zigangirova et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Targeting the Type Three Secretion System in Pseudomonas aeruginosa

(2016) Ahalieyah Anantharajah et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Differential ASC Requirements Reveal a Key Role for Neutrophils and a Noncanonical IL-1β Response to Pseudomonas aeruginosa

(2015) Yash R Patankar et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Synthesis and structure–activity relationships of novel phenoxyacetamide inhibitors of the Pseudomonas aeruginosa type III secretion system (T3SS)

(2015) John D. Williams et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Small-Molecule Inhibitors of the Type III Secretion System

(2015) Lingling Gu et al.   MOLECULES

The Role of ExoS in Dissemination of Pseudomonas aeruginosa during Pneumonia

(2015) Stephanie M. Rangel et al.   PLoS Pathogens

Small Molecule Inhibitor of Type Three Secretion Suppresses Acute and ChronicChlamydia trachomatisInfection in a Novel Urogenital Chlamydia Model

(2015) Ekaterina A. Koroleva et al.   Biomed Research International

Mutations in the Pseudomonas aeruginosa Needle Protein GenepscFConfer Resistance to Phenoxyacetamide Inhibitors of the Type III Secretion System

(2014) Nicholas O. Bowlin et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The role of the type-III secretion system of Gram-negative bacteria in the regulation of chronic infections

(2012) N. A. Zigangirova et al.   Molecular Genetics Microbiology and Virology

Acute phase response impairs host defense against Pseudomonas aeruginosa pneumonia in mice*

(2009) Rosemarijn Renckens et al.   CRITICAL CARE MEDICINE