Signalling Molecules in the Urothelium

Regulation of ACh release from guinea pig bladder urothelial cells: potential role in bladder filling sensations

(2014) L M McLatchie et al.   BRITISH JOURNAL OF PHARMACOLOGY

Cyclophosphamide-induced alterations of the micturition reflex in a novel in situ urinary bladder model in the anesthetized rat

(2014) Patrik Aronsson et al.   NEUROUROLOGY AND URODYNAMICS

ATP released via pannexin-1 hemichannels mediates bladder overactivity triggered by urothelial P2Y6 receptors

(2013) M. Alexandrina Timóteo et al.   BIOCHEMICAL PHARMACOLOGY

OnabotulinumtoxinA significantly attenuates bladder afferent nerve firing and inhibits ATP release from the urothelium

(2013) Valerie M. Collins et al.   BJU INTERNATIONAL

Dual involvements of cyclooxygenase and nitric oxide synthase expressions in ketamine-induced ulcerative cystitis in rat bladder

(2013) Shu-Mien Chuang et al.   NEUROUROLOGY AND URODYNAMICS

Roles of adenosine A1 and A2A receptors in the control of micturition in rats

(2013) Takeya Kitta et al.   NEUROUROLOGY AND URODYNAMICS

Urothelial Signaling

(2013) Lori Birder et al.   PHYSIOLOGICAL REVIEWS

Purinergic signalling in the urinary tract in health and disease

(2013) Geoffrey Burnstock   Purinergic Signalling

Pannexin 1 involvement in bladder dysfunction in a multiple sclerosis model

(2013) Hiromitsu Negoro et al.   Scientific Reports

The summary on non-reactivation cholinergic properties of oxime reactivators: the interaction with muscarinic and nicotinic receptors

(2012) O. Soukup et al.   ARCHIVES OF TOXICOLOGY

Adenosine receptor antagonism suppresses functional and histological inflammatory changes in the rat urinary bladder

(2012) Patrik Aronsson et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Muscarinic receptor subtypes involved in urothelium-derived relaxatory effects in the inflamed rat urinary bladder

(2012) M. Andersson et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

The regulation of ATP release from the urothelium by adenosine and transepithelial potential

(2012) Bryony M. Dunning-Davies et al.   BJU INTERNATIONAL

Differential expression and function of nicotinic acetylcholine receptors in the urinary bladder epithelium of the rat

(2012) Jonathan M. Beckel et al.   JOURNAL OF PHYSIOLOGY-LONDON

Sensory Dysfunction of Bladder Mucosa and Bladder Oversensitivity in a Rat Model of Metabolic Syndrome

(2012) Wei-Chia Lee et al.   PLoS One

The afferent system and its role in lower urinary tract dysfunction

(2011) Donna M Daly et al.   CURRENT OPINION IN UROLOGY

Activation of Adenosine A2AReceptors Inhibits Neutrophil Transuroepithelial Migration

(2011) Susanne Säve et al.   INFECTION AND IMMUNITY

Expression and Distribution of Ectonucleotidases in Mouse Urinary Bladder

(2011) Weiqun Yu et al.   PLoS One

Urothelial/Lamina Propria Spontaneous Activity and the Role of M3 Muscarinic Receptors in Mediating Rate Responses to Stretch and Carbachol

(2011) Christian Moro et al.   UROLOGY

Interactions Between Cholinergic and Prostaglandin Signaling Elements in the Urothelium: Role for Muscarinic Type 2 Receptors

(2011) C.J. Nile et al.   UROLOGY

Porcine Bladder Urothelial, Myofibroblast, and Detrusor Muscle Cells: Characterization and ATP Release

(2011) Ying Cheng et al.   Frontiers in Pharmacology

Examining the Role of Mechanosensitive Ion Channels in Pressure Mechanotransduction in Rat Bladder Urothelial Cells

(2010) Shawn M. Olsen et al.   ANNALS OF BIOMEDICAL ENGINEERING

Pharmacological modulation of the micturition pattern in normal and cyclophosphamide pre-treated conscious rats

(2010) M. Andersson et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Assessment and Characterization of Purinergic Contractions and Relaxations in the Rat Urinary Bladder

(2010) Patrik Aronsson et al.   BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY

Antimuscarinic Mechanisms and the Overactive Detrusor: An Update

(2010) Karl-Erik Andersson   EUROPEAN UROLOGY

The Forefront for Novel Therapeutic Agents Based on the Pathophysiology of Lower Urinary Tract Dysfunction: Pathophysiology and Pharmacotherapy of Overactive Bladder

(2010) Masaki Yoshida et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Muscarinic acetylcholine receptor subtypes expressed by mouse bladder afferent neurons

(2010) R. Nandigama et al.   NEUROSCIENCE

Extracellular adenosine triphosphate and adenosine in cancer

(2010) J Stagg et al.   ONCOGENE

Differential Roles of M2 and M3 Muscarinic Receptor Subtypes in Modulation of Bladder Afferent Activity in Rats

(2010) Yoshihiro Matsumoto et al.   UROLOGY

Removal of urothelium affects bladder contractility and release of ATP but not release of NO in rat urinary bladder

(2010) Alvaro Munoz et al.   BMC Urology

The Expression of AQP1 and eNOS in Menopausal Rat Urinary Bladder

(2010) Sun-Ouck Kim et al.   International Neurourology Journal

MicroRNAs May Mediate the Down-Regulation of Neurokinin-1 Receptor in Chronic Bladder Pain Syndrome

(2009) Veronica Sanchez Freire et al.   AMERICAN JOURNAL OF PATHOLOGY

M3muscarinic receptor expression on suburothelial interstitial cells

(2009) Simone Grol et al.   BJU INTERNATIONAL

Adenosine receptor expression inEscherichia coli-infected and cytokine-stimulated human urinary tract epithelial cells

(2009) Susanne Säve et al.   BJU INTERNATIONAL

Expression of non-neuronal cholinergic system in osteoblast-like cells and its involvement in osteogenesis

(2009) Maryam En-Nosse et al.   CELL AND TISSUE RESEARCH

Uroplakins in urothelial biology, function, and disease

(2009) Xue-Ru Wu et al.   KIDNEY INTERNATIONAL

Activation of the NLRP3 inflammasome in dendritic cells induces IL-1β–dependent adaptive immunity against tumors

(2009) François Ghiringhelli et al.   NATURE MEDICINE

Neural control of the lower urinary tract: Peripheral and spinal mechanisms

(2009) L. Birder et al.   NEUROUROLOGY AND URODYNAMICS

Muscarinic Receptor Subtypes in the Lower Urinary Tract

(2009) Daniel Giglio et al.   PHARMACOLOGY

Differential ectonucleotidase expression in human bladder cancer cell lines

(2009) Joséli Stella et al.   UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS

Mitochondrial Localization of Nitric Oxide Synthase in Partially Differentiated Urothelial Cells of Urinary Bladder Lesions

(2009) Rok Romih et al.   APPLIED IMMUNOHISTOCHEMISTRY & MOLECULAR MORPHOLOGY

Cholinergic nitric oxide release from the urinary bladder mucosa in cyclophosphamide-induced cystitis of the anaesthetized rat

(2008) M C Andersson et al.   BRITISH JOURNAL OF PHARMACOLOGY

Purinergic receptor-mediated effects of adenosine 5′-triphosphate in urological malignant diseases

(2008) Majid Shabbir et al.   INTERNATIONAL JOURNAL OF UROLOGY

MicroRNAs miR-186 and miR-150 Down-regulate Expression of the Pro-apoptotic Purinergic P2X7Receptor by Activation of Instability Sites at the 3′-Untranslated Region of the Gene That Decrease Steady-state Levels of the Transcript

(2008) Lingyin Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PACAP-Mediated ATP Release from Rat Urothelium and Regulation of PACAP/VIP and Receptor mRNA in Micturition Pathways after Cyclophosphamide (CYP)-Induced Cystitis

(2008) Beatrice M. Girard et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Activation of Muscarinic Receptors in Rat Bladder Sensory Pathways Alters Reflex Bladder Activity

(2008) F. A. Kullmann et al.   JOURNAL OF NEUROSCIENCE

Assessment of Muscarinic Receptor Subtypes in Human and Rat Lower Urinary Tract by Tissue Segment Binding Assay

(2008) Abu Syed Md Anisuzzaman et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

Distinct Apical and Basolateral Membrane Requirements for Stretch-induced Membrane Traffic at the Apical Surface of Bladder Umbrella Cells

(2008) Weiqun Yu et al.   MOLECULAR BIOLOGY OF THE CELL

Expression and functional role of β-adrenoceptors in the human urinary bladder urothelium

(2008) Atsushi Otsuka et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Nitric Oxide Mediates Stretch-Induced Ca2+ Release via Activation of Phosphatidylinositol 3-Kinase-Akt Pathway in Smooth Muscle

(2008) Bin Wei et al.   PLoS One

Muscarinic and purinergic receptor expression in the urothelium of rats with detrusor overactivity induced by bladder outlet obstruction

(2007) Joon Chul Kim et al.   BJU INTERNATIONAL

Expression and function of the P2X7 receptor in rat C6 glioma cells

(2007) Wei Wei et al.   CANCER LETTERS

ATP and acetylcholine, equal brethren

(2007) Herbert Zimmermann   NEUROCHEMISTRY INTERNATIONAL

Role of nitric oxide/cyclic GMP pathway in regulating spontaneous excitations in detrusor smooth muscle of the guinea-pig bladder

(2007) Yoshimasa Yanai et al.   NEUROUROLOGY AND URODYNAMICS