CXC and CC Chemokines as Angiogenic Modulators in Nonhaematological Tumors

CXCR4 Inhibition with AMD3100 Sensitizes Prostate Cancer to Docetaxel Chemotherapy

(2015) Urszula M. Domanska et al.   NEOPLASIA

CXCR4 Expression and Treatment with SDF-1α or Plerixafor Modulate Proliferation and Chemosensitivity of Colon Cancer Cells

(2014) Doreen Heckmann et al.   Translational Oncology

Inhibition of CXCR4–CXCL12 chemotaxis in melanoma by AMD11070

(2013) G O'Boyle et al.   BRITISH JOURNAL OF CANCER

A first-in-human, first-in-class, phase I study of carlumab (CNTO 888), a human monoclonal antibody against CC-chemokine ligand 2 in patients with solid tumors

(2013) Shahneen K. Sandhu et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Twist1 Induces CCL2 and Recruits Macrophages to Promote Angiogenesis

(2013) J. M. Low-Marchelli et al.   CANCER RESEARCH

Elevated chemokine CC-motif receptor-like 2 (CCRL2) promotes cell migration and invasion in glioblastoma

(2012) Fengqiong Yin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Inhibition of stromal CXCR4 impairs development of lung metastases

(2012) Crescenzo D’Alterio et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Suppression of metastases of small cell lung cancer cells in mice by a peptidic CXCR4 inhibitor TF14016

(2012) Yasushi Otani et al.   FEBS LETTERS

Role and clinicopathologic significance of CXC chemokine ligand 16 and chemokine (C-X-C motif) receptor 6 expression in gastric carcinomas

(2012) Ya-nan Xing et al.   HUMAN PATHOLOGY

Inhibition of CXCR2 profoundly suppresses inflammation-driven and spontaneous tumorigenesis

(2012) Thomas Jamieson et al.   JOURNAL OF CLINICAL INVESTIGATION

In vitro and in vivo therapeutic efficacy of CXCR4 antagonist BKT140 against human non–small cell lung cancer

(2012) Duha Fahham et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

Antimetastatic effect of nobiletin through the down-regulation of CXC chemokine receptor type 4 and matrix metallopeptidase-9

(2012) Seung Ho Baek et al.   PHARMACEUTICAL BIOLOGY

CXCR4 Inhibitors: Tumor Vasculature and Therapeutic Challenges

(2012) Filomena de Nigris et al.   Recent Patents on Anti-Cancer Drug Discovery

G31P, an Antagonist against CXC Chemokine Receptors 1 and 2, Inhibits Growth of Human Prostate Cancer Cells in Nude Mice

(2012) Xin Liu et al.   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE

CXCL13/CXCR5 signaling enhances BCR-triggered B-cell activation by shaping cell dynamics

(2011) J. Saez de Guinoa et al.   BLOOD

Potential of CXCR4 antagonists for the treatment of metastatic lung cancer

(2011) Jan A Burger et al.   Expert Review of Anticancer Therapy

The chemokine CXCL12 and its receptor CXCR4 promote glioma stem cell-mediated VEGF production and tumour angiogenesis via PI3K/AKT signalling

(2011) Yi-fang Ping et al.   JOURNAL OF PATHOLOGY

Expression and potential role of chemokine receptor CXCR4 in human bladder carcinoma cell lines with different metastatic ability

(2011) Delin Yang   Molecular Medicine Reports

CXCR4/SDF-1 axis is involved in lymph node metastasis of gastric carcinoma

(2011) Bao-Cheng Zhao   WORLD JOURNAL OF GASTROENTEROLOGY

Chemokine growth-regulated oncogene 1 as a putative biomarker for gastric cancer progression

(2010) Jae-Joon Jung et al.   CANCER SCIENCE

Chemokine receptor CXCR3 promotes growth of glioma

(2010) Che Liu et al.   CARCINOGENESIS

Inflammatory and MicroRNA Gene Expression as Prognostic Classifier of Barrett's-Associated Esophageal Adenocarcinoma

(2010) G. H. Nguyen et al.   CLINICAL CANCER RESEARCH

Blockade of CXCR4 in oral squamous cell carcinoma inhibits lymph node metastases

(2010) Daisuke Uchida et al.   EUROPEAN JOURNAL OF CANCER

Expression of angiostatic platelet factor-4var/CXCL4L1 counterbalances angiogenic impulses of vascular endothelial growth factor, interleukin-8/CXCL8, and stromal cell-derived factor 1/CXCL12 in esophageal and colorectal cancer

(2010) Hannelien Verbeke et al.   HUMAN PATHOLOGY

CXCR4 peptide antagonist inhibits primary breast tumor growth, metastasis and enhances the efficacy of anti-VEGF treatment or docetaxel in a transgenic mouse model

(2010) Saima Hassan et al.   INTERNATIONAL JOURNAL OF CANCER

IL-8 is a mediator of NF-κB induced invasion by gliomas

(2010) Baisakhi Raychaudhuri et al.   JOURNAL OF NEURO-ONCOLOGY

Transcriptional control of melanoma metastasis: The importance of the tumor microenvironment

(2010) Russell R. Braeuer et al.   SEMINARS IN CANCER BIOLOGY

Angiogenesis and ovarian cancer

(2009) César Gómez-Raposo et al.   Clinical & Translational Oncology

Gene expression analysis identifies over-expression ofCXCL1,SPARC,SPP1, andSULF1in gastric cancer

(2009) Siina Junnila et al.   GENES CHROMOSOMES & CANCER

TNF-α and the IFN-γ-inducible protein 10 (IP-10/CXCL-10) delivered by parvoviral vectors act in synergy to induce antitumor effects in mouse glioblastoma

(2008) M Enderlin et al.   CANCER GENE THERAPY

Elevation of circulating interleukin-8 is related to lymph node and distant metastases in esophageal squamous cell carcinomas—Implication for clinical evaluation of cancer patient

(2008) Malgorzata Krzystek-Korpacka et al.   CYTOKINE

Multi-faceted roles for CXC-chemokines in prostate cancer progression

(2008) David et al.   Frontiers in Bioscience-Landmark

Monocyte Chemotactic Protein (MCP)-1 Promotes Angiogenesis via a Novel Transcription Factor, MCP-1-induced Protein (MCPIP)

(2008) Jianli Niu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Chemokines in Angiogenesis: CXCL12/SDF-1 and CXCR4 Interaction, a Key Regulator of Endothelial Cell Responses

(2003) ROSALBA SALCEDO et al.   MICROCIRCULATION