Bimodal Imaging Probes for Combined PET and OI: Recent Developments and Future Directions for Hybrid Agent Development

Multimodal Imaging of Integrin Receptor-Positive Tumors by Bioluminescence, Fluorescence, Gamma Scintigraphy, and Single-Photon Emission Computed Tomography Using a Cyclic RGD Peptide Labeled with a Near-Infrared Fluorescent Dye and a Radionuclide

(2018) W. Barry Edwards et al.   Molecular Imaging

Intraoperative Imaging of Positron Emission Tomographic Radiotracers Using Cerenkov Luminescence Emissions

(2018) Jason P. Holland et al.   Molecular Imaging

Detection of Cancer Metastases with a Dual-labeled Near-Infrared/Position Emission Tomography Imaging Agent

(2014) Lakshmi Sampath et al.   Translational Oncology

68Ga/DOTA- and 64Cu/NOTA-Phthalocyanine Conjugates as Fluorescent/PET Bimodal Imaging Probes

(2013) Elena Ranyuk et al.   BIOCONJUGATE CHEMISTRY

Recent advances in multifunctional magnetic nanoparticles and applications to biomedical diagnosis and treatment

(2013) Kai Yan et al.   RSC Advances

Biologically-Targeted Detection of Primary and Micro-Metastatic Ovarian Cancer

(2013) Tracy W. Liu et al.   Theranostics

Synthesis of [18F]BODIPY: Bifunctional Reporter for Hybrid Optical/Positron Emission Tomography Imaging

(2012) J. Adam Hendricks et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Novel Multifunctional Theranostic Liposome Drug Delivery System: Construction, Characterization, and Multimodality MR, Near-Infrared Fluorescent, and Nuclear Imaging

(2012) Shihong Li et al.   BIOCONJUGATE CHEMISTRY

Incorporation of paramagnetic, fluorescent and PET/SPECT contrast agents into liposomes for multimodal imaging

(2012) Nick Mitchell et al.   BIOMATERIALS

Imaging agents for the chemokine receptor 4 (CXCR4)

(2012) Joeri Kuil et al.   CHEMICAL SOCIETY REVIEWS

DOTAGA-Anhydride: A Valuable Building Block for the Preparation of DOTA-Like Chelating Agents

(2012) Claire Bernhard et al.   CHEMISTRY-A EUROPEAN JOURNAL

Quantifying multimodal contrast agent biological activity using near-infrared flow cytometry

(2012) Mary A. Hall et al.   Contrast Media & Molecular Imaging

Clinically-translated silica nanoparticles as dual-modality cancer-targeted probes for image-guided surgery and interventions

(2012) Michelle S. Bradbury et al.   Integrative Biology

Multimodal Chelation Platform for Near-Infrared Fluorescence/Nuclear Imaging

(2012) Sukhen C. Ghosh et al.   JOURNAL OF MEDICINAL CHEMISTRY

Efficient Construction of PET/Fluorescence Probe Based on Sarcophagine Cage: An Opportunity to Integrate Diagnosis with Treatment

(2012) Shuanglong Liu et al.   MOLECULAR IMAGING AND BIOLOGY

Multimodality Imaging of Breast Cancer Experimental Lung Metastasis with Bioluminescence and a Monoclonal Antibody Dual-Labeled with 89Zr and IRDye 800CW

(2012) Hao Hong et al.   MOLECULAR PHARMACEUTICS

Positron Emission Tomography and Optical Imaging of Tumor CD105 Expression with a Dual-Labeled Monoclonal Antibody

(2012) Yin Zhang et al.   MOLECULAR PHARMACEUTICS

A novel sulfonated prosthetic group for [18F]-radiolabelling and imparting water solubility of biomolecules and cyanine fluorophores

(2012) Thomas Priem et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Nuclear (PET/SPECT) and optical imaging probes targeting the CXCR4 chemokine receptor

(2012) James C. Knight et al.   MedChemComm

Synthesis, radiometal labeling and in vitro evaluation of a targeted PPIX derivative

(2011) Babak Behnam Azad et al.   APPLIED RADIATION AND ISOTOPES

Synthesis and Evaluation of a Bimodal CXCR4 Antagonistic Peptide

(2011) Joeri Kuil et al.   BIOCONJUGATE CHEMISTRY

Multifunctional rare-earth self-assembled nanosystem for tri-modal upconversion luminescence /fluorescence /positron emission tomography imaging

(2011) Qian Liu et al.   BIOMATERIALS

Characterization of chemical, radiochemical and optical properties of a dual-labeled MMP-9 targeting peptide

(2011) Ali Azhdarinia et al.   BIOORGANIC & MEDICINAL CHEMISTRY

PET imaging using 64Cu-labeled sulfophthalocyanines: Synthesis and biodistribution

(2011) Elena R. Ranyuk et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Chelating Agents and their Use in Radiopharmaceutical Sciences

(2011) B. Wangler et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Hybrid Peptide Dendrimers for Imaging of Chemokine Receptor 4 (CXCR4) Expression

(2011) Joeri Kuil et al.   MOLECULAR PHARMACEUTICS

Chimeric Ferritin Nanocages for Multiple Function Loading and Multimodal Imaging

(2011) Xin Lin et al.   NANO LETTERS

Development and in vivo imaging of a PET/MRI nanoprobe with enhanced NIR fluorescence by dye encapsulation

(2011) Jun Sung Kim et al.   Nanomedicine

Intraoperative tumor-specific fluorescence imaging in ovarian cancer by folate receptor-α targeting: first in-human results

(2011) Gooitzen M van Dam et al.   NATURE MEDICINE

Non-Invasive Imaging of Cysteine Cathepsin Activity in Solid Tumors Using a 64Cu-Labeled Activity-Based Probe

(2011) Gang Ren et al.   PLoS One

A Dual-Labeled Knottin Peptide for PET and Near-Infrared Fluorescence Imaging of Integrin Expression in Living Subjects

(2010) Richard H. Kimura et al.   BIOCONJUGATE CHEMISTRY

Fast18F Labeling of a Near-Infrared Fluorophore Enables Positron Emission Tomography and Optical Imaging of Sentinel Lymph Nodes

(2010) Richard Ting et al.   BIOCONJUGATE CHEMISTRY

PET/NIRF/MRI triple functional iron oxide nanoparticles

(2010) Jin Xie et al.   BIOMATERIALS

Fluorine-18-labeled Gd3+/Yb3+/Er3+ co-doped NaYF4 nanophosphors for multimodality PET/MR/UCL imaging

(2010) Jing Zhou et al.   BIOMATERIALS

Multimodality Imaging Probes: Design and Challenges

(2010) Angelique Louie   CHEMICAL REVIEWS

(Non-targeted) radioactive/fluorescent nanoparticles and their potential in combined pre- and intraoperative imaging during sentinel lymph node resection

(2010) Tessa Buckle et al.   NANOTECHNOLOGY

Hybrid PET-optical imaging using targeted probes

(2010) Matthias Nahrendorf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Paradoxical glomerular filtration of carbon nanotubes

(2010) A. Ruggiero et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Facile Preparation of a Hybrid Nanoprobe for Triple-Modality Optical/PET/MR Imaging

(2010) Jeong Chan Park et al.   Small

Development of a Quadruple Imaging Modality by Using Nanoparticles

(2009) Do Won Hwang et al.   CHEMISTRY-A EUROPEAN JOURNAL

Value of SPECT/CT for Detection and Anatomic Localization of Sentinel Lymph Nodes Before Laparoscopic Sentinel Node Lymphadenectomy in Prostate Carcinoma

(2009) L. Vermeeren et al.   JOURNAL OF NUCLEAR MEDICINE

Modification of Aminosilanized Superparamagnetic Nanoparticles: Feasibility of Multimodal Detection Using 3T MRI, Small Animal PET, and Fluorescence Imaging

(2009) Lars Stelter et al.   MOLECULAR IMAGING AND BIOLOGY

Dual functional molecular imaging probe targeting CD20 with PET and optical imaging

(2009) Paudyal   ONCOLOGY REPORTS

Multimodality Imaging: Beyond PET/CT and SPECT/CT

(2009) Simon R. Cherry   SEMINARS IN NUCLEAR MEDICINE

Synergistically Integrated Nanoparticles as Multimodal Probes for Nanobiotechnology

(2008) Jinwoo Cheon et al.   ACCOUNTS OF CHEMICAL RESEARCH

Fluorine-18-Labeled Phospholipid Quantum Dot Micelles forin VivoMultimodal Imaging from Whole Body to Cellular Scales

(2008) Frédéric Ducongé et al.   BIOCONJUGATE CHEMISTRY

Dual-modality optical and positron emission tomography imaging of vascular endothelial growth factor receptor on tumor vasculature using quantum dots

(2008) Kai Chen et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Near infrared fluorescent optical imaging for nodal staging

(2008) Lakshmi Sampath et al.   JOURNAL OF BIOMEDICAL OPTICS

Sentinel Node Biopsy: Interpretation and Management of Patients With Immunohistochemistry-Positive Sentinel Nodes and Those With Micrometastases

(2008) Emiel J.T. Rutgers   JOURNAL OF CLINICAL ONCOLOGY

Synthesis, Characterization, and Biological Evaluation of Integrin αvβ3-Targeted PAMAM Dendrimers

(2008) C. Andrew Boswell et al.   MOLECULAR PHARMACEUTICS

Agonist−Antagonist Dilemma in Molecular Imaging: Evaluation of a Monomolecular Multimodal Imaging Agent for the Somatostatin Receptor

(2007) W. Barry Edwards et al.   BIOCONJUGATE CHEMISTRY

Nanoparticle PET-CT Imaging of Macrophages in Inflammatory Atherosclerosis

(2007) Matthias Nahrendorf et al.   CIRCULATION