Deregulation of Bone Forming Cells in Bone Diseases and Anabolic Effects of Strontium-Containing Agents and Biomaterials

Current perspectives on parathyroid hormone (PTH) and PTH-related protein (PTHrP) as bone anabolic therapies

(2013) Pedro Esbrit et al.   BIOCHEMICAL PHARMACOLOGY

Early osseointegration of a strontium containing glass ceramic in a rabbit model

(2013) Arumugan Sabareeswaran et al.   BIOMATERIALS

Enhanced osteoporotic bone regeneration by strontium-substituted calcium silicate bioactive ceramics

(2013) Kaili Lin et al.   BIOMATERIALS

Intervention timing of strontium treatment on estrogen depletion-induced osteoporosis in rats: Bone microstructure and mechanics

(2013) Songlin Peng et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Biomimetic magnesium–carbonate-apatite nanocrystals endowed with strontium ions as anti-osteoporotic trigger

(2013) Michele Iafisco et al.   Materials Science & Engineering C-Materials for Biological Applications

WNT signaling in bone homeostasis and disease: from human mutations to treatments

(2013) Roland Baron et al.   NATURE MEDICINE

Strontium ranelate rebalances bone marrow adipogenesis and osteoblastogenesis in senescent osteopenic mice through NFATc/Maf and Wnt signaling

(2012) Zuzana Saidak et al.   AGING CELL

Senescence-associated intrinsic mechanisms of osteoblast dysfunctions

(2011) Moustapha Kassem et al.   AGING CELL

The cross-talk between osteoclasts and osteoblasts in response to strontium treatment: Involvement of osteoprotegerin

(2011) Songlin Peng et al.   BONE

Activation of FGF Receptors is a new Mechanism by which Strontium Ranelate Induces Osteoblastic Cell Growth

(2011) Joseph Caverzasio et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The Effect of Antiresorptives on Bone Quality

(2011) Robert R. Recker et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Osteoblasts in osteoporosis: past, emerging, and future anabolic targets

(2011) Pierre J Marie et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

Bone proteins PHEX and DMP1 regulate fibroblastic growth factor Fgf23 expression in osteocytes through a common pathway involving FGF receptor (FGFR) signaling

(2011) Aline Martin et al.   FASEB JOURNAL

An Akt-dependent Increase in Canonical Wnt Signaling and a Decrease in Sclerostin Protein Levels Are Involved in Strontium Ranelate-induced Osteogenic Effects in Human Osteoblasts

(2011) Mark S. Rybchyn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Osteoprotegerin deficiency attenuates strontium-mediated inhibition of osteoclastogenesis and bone resorption

(2011) Songlin Peng et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Extrinsic Mechanisms Involved in Age-Related Defective Bone Formation

(2011) Pierre J. Marie et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Strontium- and Zinc-Alginate Hydrogels for Bone Tissue Engineering

(2011) Elsie S. Place et al.   TISSUE ENGINEERING PART A

Vitamin K2 stimulates osteoblastogenesis and suppresses osteoclastogenesis by suppressing NF-κB activation

(2010) Masayoshi Yamaguchi   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Cellular and Molecular Mechanisms of Bone Remodeling

(2010) Liza J. Raggatt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel method for local administration of strontium from implant surfaces

(2010) Johan Forsgren et al.   JOURNAL OF MATERIALS SCIENCE-MATERIALS IN MEDICINE

In vivo anabolic effect of strontium on trabecular bone was associated with increased osteoblastogenesis of bone marrow stromal cells

(2010) Songlin Peng et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Mechanical signals as anabolic agents in bone

(2010) Engin Ozcivici et al.   Nature Reviews Rheumatology

What old means to bone

(2010) Stavros C. Manolagas et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Genetic and Transcriptional Control of Bone Formation

(2010) Amjad Javed et al.   Oral and Maxillofacial Surgery Clinics of North America

Secondary osteoporosis in patients with an osteoporotic fracture

(2009) C. Kok et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

Molecular determinants of non-competitive antagonist binding to the mouse GPRC6A receptor

(2009) Helene Faure et al.   CELL CALCIUM

Strontium Promotes Osteogenic Differentiation of Mesenchymal Stem Cells Through the Ras/MAPK Signaling Pathway

(2009) Songlin Peng et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

Restoration of regenerative osteoblastogenesis in aged mice: Modulation of TNF

(2009) Elizabeth C Wahl et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Calcium sensing receptor-dependent and receptor-independent activation of osteoblast replication and survival by strontium ranelate

(2009) Olivia Fromigué et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Strontium borate glass: potential biomaterial for bone regeneration

(2009) H. B. Pan et al.   Journal of the Royal Society Interface

Inhibition of osteoblastic bone formation by nuclear factor-κB

(2009) Jia Chang et al.   NATURE MEDICINE

Wnt and PPARγ signaling in osteoblastogenesis and adipogenesis

(2009) Ichiro Takada et al.   Nature Reviews Rheumatology

Proinflammatory cytokines and osteoporosis

(2009) Robert R. McLean   Current Osteoporosis Reports

Transcriptional Control of Skeletogenesis

(2008) Gerard Karsenty   Annual Review of Genomics and Human Genetics

The effect of strontium ranelate on serum insulin like growth factor-1 and leptin levels in osteoporotic post-menopausal women: a prospective study

(2008) Ibrahim Gulhan et al.   ARCHIVES OF GYNECOLOGY AND OBSTETRICS

Ubiquitin Ligase Smurf1 Mediates Tumor Necrosis Factor-induced Systemic Bone Loss by Promoting Proteasomal Degradation of Bone Morphogenetic Signaling Proteins

(2008) Ruolin Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Coupling of Smad and Runx2 for Execution of the BMP2 Osteogenic Signal

(2008) Amjad Javed et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Building bone to reverse osteoporosis and repair fractures

(2008) Sundeep Khosla et al.   JOURNAL OF CLINICAL INVESTIGATION

Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation

(2008) Matthew J Hilton et al.   NATURE MEDICINE

Strontium ranelate treatment of human primary osteoblasts promotes an osteocyte-like phenotype while eliciting an osteoprotegerin response

(2008) G. J. Atkins et al.   OSTEOPOROSIS INTERNATIONAL

Strontium ranelate improves bone strength in ovariectomized rat by positively influencing bone resistance determinants

(2008) S. D. Bain et al.   OSTEOPOROSIS INTERNATIONAL