Early Alzheimer’s and Parkinson’s Disease Pathology in Urban Children: Friend versus Foe Responses—It Is Time to Face the Evidence

The Canine (Dog) Model of Human Aging and Disease: Dietary, Environmental and Immunotherapy Approaches

(2017) Carl W. Cotman et al.   JOURNAL OF ALZHEIMERS DISEASE

Intra-city Differences in Cardiac Expression of Inflammatory Genes and Inflammasomes in Young Urbanites: A Pilot Study

(2015) Rodolfo Villarreal-Calderon et al.   Journal of Toxicologic Pathology

The release of S-100B and NSE in severe traumatic head injury is associated with APOE ε4

(2012) Zandra Olivecrona et al.   ACTA NEUROCHIRURGICA

Inflammasomes and Their Roles in Health and Disease

(2012) Mohamed Lamkanfi et al.   Annual Review of Cell and Developmental Biology

Pathogenesis and Disease-modifying Therapy in Alzheimer's Disease: The Flat Line of Progress

(2012) Rudy J. Castellani et al.   ARCHIVES OF MEDICAL RESEARCH

A turning point for Alzheimer's disease?

(2012) Jack C. de la Torre   BIOFACTORS

Inflammasome formation and IL-1β release by human blood monocytes in response to silver nanoparticles

(2012) Eun-Jeong Yang et al.   BIOMATERIALS

Neurotoxicity of Engineered Nanoparticles from Metals

(2012) Hari Shanker Sharma et al.   CNS & Neurological Disorders-Drug Targets

Long-Term Exposure to Outdoor Air Pollution and Incidence of Cardiovascular Diseases

(2012) Richard W. Atkinson et al.   EPIDEMIOLOGY

Chronic noise exposure causes persistence of tau hyperphosphorylation and formation of NFT tau in the rat hippocampus and prefrontal cortex

(2012) Bo Cui et al.   EXPERIMENTAL NEUROLOGY

Revisiting oxidative stress and mitochondrial dysfunction in the pathogenesis of Parkinson disease—resemblance to the effect of amphetamine drugs of abuse

(2012) Rita Perfeito et al.   FREE RADICAL BIOLOGY AND MEDICINE

Acute lipopolysaccharide priming boosts inflammasome activation independently of inflammasome sensor induction

(2012) Kate Schroder et al.   IMMUNOBIOLOGY

Proteomic atlas of the human olfactory bulb

(2012) Joaquín Fernández-Irigoyen et al.   Journal of Proteomics

Cognitive reserve in ageing and Alzheimer's disease

(2012) Yaakov Stern   LANCET NEUROLOGY

Pathogenesis of Parkinson's disease

(2012) Etienne C. Hirsch et al.   MOVEMENT DISORDERS

Effects of copper nanoparticles on rat cerebral microvessel endothelial cells

(2012) William J Trickler et al.   Nanomedicine

Olfactory dysfunction in Parkinson disease

(2012) Richard L. Doty   Nature Reviews Neurology

Oxidative Damage to RNA in Aging and Neurodegenerative Disorders

(2012) Akihiko Nunomura et al.   NEUROTOXICITY RESEARCH

When does Parkinson's disease begin? From prodromal disease to motor signs

(2012) W.G. Meissner   REVUE NEUROLOGIQUE

Short-term effects of ambient air pollution on stroke: Who is most vulnerable?

(2012) Paul J. Villeneuve et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Toll-like receptor (TLR) and inflammasome actions in the central nervous system

(2012) Richa Hanamsagar et al.   TRENDS IN IMMUNOLOGY

Neurotoxicity of Silica Nanoparticles: Brain Localization and Dopaminergic Neurons Damage Pathways

(2011) Jie Wu et al.   ACS Nano

Characterization of AβpN3 deposition in the brains of dogs of various ages and other animal species

(2011) James K. Chambers et al.   AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS

Molecular Mechanisms and Pathological Consequences of Endotoxin Tolerance and Priming

(2011) Matthew Morris et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Exposure to severe urban air pollution influences cognitive outcomes, brain volume and systemic inflammation in clinically healthy children

(2011) Lilian Calderón-Garcidueñas et al.   BRAIN AND COGNITION

Olfactory ERPs in an odor/visual congruency task differentiate ApoE ε4 carriers from non-carriers

(2011) Joel Kowalewski et al.   BRAIN RESEARCH

Chronic Fine Particulate Matter Exposure Induces Systemic Vascular Dysfunction via NADPH Oxidase and TLR4 Pathways

(2011) Thomas Kampfrath et al.   CIRCULATION RESEARCH

A Novel Perspective on Tau in Alzheimers Disease

(2011) D. J. Bonda et al.   Current Alzheimer Research

Diesel Exhaust Activates and Primes Microglia: Air Pollution, Neuroinflammation, and Regulation of Dopaminergic Neurotoxicity

(2011) Shannon Levesque et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Fine and ultrafine particles emitted from laser printers as indoor air contaminants in German offices

(2011) Tao Tang et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

High ability of apolipoprotein E4 to stabilize amyloid-β peptide oligomers, the pathological entities responsible for Alzheimer's disease

(2011) Emilie Cerf et al.   FASEB JOURNAL

Air pollution is associated with brainstem auditory nuclei pathology and delayed brainstem auditory evoked potentials

(2011) Lilian Calderón-Garcidueñas et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE

Nanoparticles and Neurotoxicity

(2011) Tin-Tin Win-Shwe et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Interaction between pathogenic proteins in neurodegenerative disorders

(2011) Kurt A. Jellinger   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Histopathological and Immunohistochemical Comparison of the Brain of Human Patients with Alzheimer’s Disease and the Brain of Aged Dogs with Cognitive Dysfunction

(2011) C.-H. Yu et al.   JOURNAL OF COMPARATIVE PATHOLOGY

Stages of the Pathologic Process in Alzheimer Disease: Age Categories From 1 to 100 Years

(2011) Heiko Braak et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

White matter lesions in Parkinson disease

(2011) Nicolaas I. Bohnen et al.   Nature Reviews Neurology

Olfaction in Parkinson's disease and related disorders

(2011) Richard L. Doty   NEUROBIOLOGY OF DISEASE

Inflammatory Markers and Neuropsychological Functioning: The Framingham Heart Study

(2011) Angela L. Jefferson et al.   NEUROEPIDEMIOLOGY

Neurological impacts from inhalation of pollutants and the nose–brain connection

(2011) R.G. Lucchini et al.   NEUROTOXICOLOGY

7 Billion and Counting

(2011) D. E. Bloom   SCIENCE

White Matter Hyperintensity Penumbra

(2011) Pauline Maillard et al.   STROKE

Microglial activation, recruitment and phagocytosis as linked phenomena in ferric oxide nanoparticle exposure

(2011) Yun Wang et al.   TOXICOLOGY LETTERS

The pathological process underlying Alzheimer’s disease in individuals under thirty

(2010) Heiko Braak et al.   ACTA NEUROPATHOLOGICA

Functional Impact of White Matter Hyperintensities in Cognitively Normal Elderly Subjects

(2010) Melissa E. Murray et al.   ARCHIVES OF NEUROLOGY

Tau cleavage and tau aggregation in neurodegenerative disease: Figure 1

(2010) Diane P. Hanger et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

From tau phosphorylation to tau aggregation: what about neuronal death?: Figure 1

(2010) Luc Buée et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Particulate Matter Air Pollution and Cardiovascular Disease

(2010) Robert D. Brook et al.   CIRCULATION

The inflammasomes: mechanisms of activation and function

(2010) Eicke Latz   CURRENT OPINION IN IMMUNOLOGY

Signaling by ROS drives inflammasome activation

(2010) Fabio Martinon   EUROPEAN JOURNAL OF IMMUNOLOGY

Urban Air Pollution Targets the Dorsal Vagal Complex and Dark Chocolate Offers Neuroprotection

(2010) Rafael Villarreal-Calderon et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

Heterogeneity of small vessel disease: a systematic review of MRI and histopathology correlations

(2010) A. A. Gouw et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Caspase activation precedes and leads to tangles

(2010) Alix de Calignon et al.   NATURE

Cognitive Deficits Are Associated with Frontal and Temporal Lobe White Matter Lesions in Middle-Aged Adults Living in the Community

(2010) David Bunce et al.   PLoS One

Symposium Overview

(2009) Richard L. Doty   Annals of the New York Academy of Sciences

Urban air pollution: Influences on olfactory function and pathology in exposed children and young adults

(2009) Lilian Calderón-Garcidueñas et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Particulate Matter Induced Enhancement of Inflammatory Markers in the Brains of Apolipoprotein E Knockout Mice

(2009) Arezoo Campbell et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

Nanoparticles and the Brain: Cause for Concern?

(2009) Günter Oberdörster et al.   JOURNAL OF NANOSCIENCE AND NANOTECHNOLOGY

T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes

(2009) Greta Guarda et al.   NATURE

Age-associated leukoaraiosis and cortical cholinergic deafferentation

(2009) N. I. Bohnen et al.   NEUROLOGY

Cognitive impairment risk: White matter hyperintensity progression matters

(2009) L. C. Silbert et al.   NEUROLOGY

Reduction in cerebral blood flow in areas appearing as white matter hyperintensities on magnetic resonance imaging

(2009) Adam M. Brickman et al.   PSYCHIATRY RESEARCH-NEUROIMAGING

Clean Air for Megacities

(2009) D. D. Parrish et al.   SCIENCE

Immunotoxicity and Environment: Immunodysregulation and Systemic Inflammation in Children

(2009) Lilian Calderón-Garcidueñas et al.   TOXICOLOGIC PATHOLOGY

Air pollution: mechanisms of neuroinflammation and CNS disease

(2009) Michelle L. Block et al.   TRENDS IN NEUROSCIENCES

Air pollution, cognitive deficits and brain abnormalities: A pilot study with children and dogs

(2008) Lilian Calderón-Garcidueñas et al.   BRAIN AND COGNITION

Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier

(2008) Anika M. S. Hartz et al.   FASEB JOURNAL

Particulate matter, oxidative stress and neurotoxicity

(2008) Sheba M.J. MohanKumar et al.   NEUROTOXICOLOGY

Innate Immune Activation Through Nalp3 Inflammasome Sensing of Asbestos and Silica

(2008) C. Dostert et al.   SCIENCE

Long-term Air Pollution Exposure Is Associated with Neuroinflammation, an Altered Innate Immune Response, Disruption of the Blood-Brain Barrier, Ultrafine Particulate Deposition, and Accumulation of Amyloid β-42 and α-Synuclein in Children and Young Adults

(2008) Lilian Calderón-Garcidueñas et al.   TOXICOLOGIC PATHOLOGY

Air pollution and population health: a global challenge

(2008) Bingheng Chen et al.   Environmental Health and Preventive Medicine