Malaria Vaccine Adjuvants: Latest Update and Challenges in Preclinical and Clinical Research
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Title
Malaria Vaccine Adjuvants: Latest Update and Challenges in Preclinical and Clinical Research
Authors
Keywords
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Journal
Biomed Research International
Volume 2013, Issue -, Pages 1-19
Publisher
Hindawi Limited
Online
2013-04-24
DOI
10.1155/2013/282913
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Note: Only part of the references are listed.- Cutting Edge: Alum Adjuvant Stimulates Inflammatory Dendritic Cells through Activation of the NALP3 Inflammasome
- (2014) M. Kool et al. JOURNAL OF IMMUNOLOGY
- The Adjuvants Aluminum Hydroxide and MF59 Induce Monocyte and Granulocyte Chemoattractants and Enhance Monocyte Differentiation toward Dendritic Cells
- (2014) A. Seubert et al. JOURNAL OF IMMUNOLOGY
- Clinical Assessment of a Recombinant Simian Adenovirus ChAd63: A Potent New Vaccine Vector
- (2012) Geraldine A. O’Hara et al. JOURNAL OF INFECTIOUS DISEASES
- ChAd63-MVA–vectored Blood-stage Malaria Vaccines Targeting MSP1 and AMA1: Assessment of Efficacy Against Mosquito Bite Challenge in Humans
- (2012) Susanne H Sheehy et al. MOLECULAR THERAPY
- A Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Infants
- (2012) NEW ENGLAND JOURNAL OF MEDICINE
- The Th1 Immune Response toPlasmodium falciparumCircumsporozoite Protein Is Boosted by Adenovirus Vectors 35 and 26 with a Homologous Insert
- (2011) Katarina Radošević et al. Clinical and Vaccine Immunology
- Effect on Cellular and Humoral Immune Responses of the AS03 Adjuvant System in an A/H1N1/2009 Influenza Virus Vaccine Administered to Adults during Two Randomized Controlled Trials
- (2011) François Roman et al. Clinical and Vaccine Immunology
- An Adjuvanted Polyprotein HIV-1 Vaccine Induces Polyfunctional Cross-Reactive CD4+ T Cell Responses in Seronegative Volunteers
- (2011) Eva Van Braeckel et al. CLINICAL INFECTIOUS DISEASES
- Viral vectors as vaccine platforms: deployment in sight
- (2011) Christine S Rollier et al. CURRENT OPINION IN IMMUNOLOGY
- Targeting of Toll-like receptors: a decade of progress in combating infectious diseases
- (2011) Mona Hedayat et al. LANCET INFECTIOUS DISEASES
- Safety and immunogenicity of multi-antigen AMA1-based vaccines formulated with CoVaccine HT™ and Montanide ISA 51 in rhesus macaques
- (2011) Kwadwo A Kusi et al. MALARIA JOURNAL
- Phase Ia Clinical Evaluation of the Plasmodium falciparum Blood-stage Antigen MSP1 in ChAd63 and MVA Vaccine Vectors
- (2011) Susanne H Sheehy et al. MOLECULAR THERAPY
- First Results of Phase 3 Trial of RTS,S/AS01 Malaria Vaccine in African Children
- (2011) NEW ENGLAND JOURNAL OF MEDICINE
- A human Phase I/IIa malaria challenge trial of a polyprotein malaria vaccine
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- (2011) Ida Rosenkrands et al. VACCINE
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- (2011) Sandra Morel et al. VACCINE
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- (2011) Philippe Denoël et al. VACCINE
- A synthetic TLR4 agonist formulated in an emulsion enhances humoral and Type 1 cellular immune responses against GMZ2 – A GLURP–MSP3 fusion protein malaria vaccine candidate
- (2011) Susana Lousada-Dietrich et al. VACCINE
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- (2011) Aiala Salvador et al. VACCINE
- In Vivo Protection Provided by a Synthetic New Alpha-Galactosyl Ceramide Analog against Bacterial and Viral Infections in Murine Models
- (2010) K.-H. Lin et al. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY
- CpG Oligodeoxynucleotides as TLR9 Agonists
- (2010) Gaurav K. Gupta et al. BIODRUGS
- Safety and Immunogenicity of a Recombinant Nonglycosylated Erythrocyte Binding Antigen 175 Region II Malaria Vaccine in Healthy Adults Living in an Area Where Malaria Is Not Endemic
- (2010) H. M. El Sahly et al. Clinical and Vaccine Immunology
- Clinical development of a novel CD1d-binding NKT cell ligand as a vaccine adjuvant
- (2010) Neal N. Padte et al. CLINICAL IMMUNOLOGY
- New adjuvants for human vaccines
- (2010) M Lamine Mbow et al. CURRENT OPINION IN IMMUNOLOGY
- Identification and functions of pattern-recognition receptors
- (2010) Yutaro Kumagai et al. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY
- Evidences of protection against blood-stage infection of Plasmodium falciparum by the novel protein vaccine SE36
- (2010) Toshihiro Horii et al. PARASITOLOGY INTERNATIONAL
- Safety and Immunogenicity of an AMA1 Malaria Vaccine in Malian Children: Results of a Phase 1 Randomized Controlled Trial
- (2010) Mahamadou A. Thera et al. PLoS One
- Phase 1 Trial of the Plasmodium falciparum Blood Stage Vaccine MSP142-C1/Alhydrogel with and without CPG 7909 in Malaria Naïve Adults
- (2010) Ruth D. Ellis et al. PLoS One
- Safety, Immunogenicity and Duration of Protection of the RTS,S/AS02D Malaria Vaccine: One Year Follow-Up of a Randomized Controlled Phase I/IIb Trial
- (2010) Pedro Aide et al. PLoS One
- Design of a potent CD1d-binding NKT cell ligand as a vaccine adjuvant
- (2010) X. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Randomized double-blind controlled Phase I/IIa trial to assess the efficacy of malaria vaccine PfCS102 to protect against challenge with P. falciparum
- (2010) Blaise Genton et al. VACCINE
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- (2010) Daniel Y. Bargieri et al. VACCINE
- Phase 1 safety and immunogenicity trial of the Plasmodium falciparum blood-stage malaria vaccine AMA1-C1/ISA 720 in Australian adults
- (2010) Mark A. Pierce et al. VACCINE
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- (2010) Stefania Capone et al. VACCINE
- Poly(I:C) is an effective adjuvant for antibody and multi-functional CD4+ T cell responses to Plasmodium falciparum circumsporozoite protein (CSP) and αDEC-CSP in non human primates
- (2010) Kavita Tewari et al. VACCINE
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- (2010) Sofia Casares et al. VACCINE
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- (2010) Christian L. Tielemans et al. VACCINE
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- (2009) Issaka Sagara et al. VACCINE
- Topical resiquimod promotes priming of CTL to parenteral antigens
- (2009) Brent A. Chang et al. VACCINE
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- (2009) Meral Esen et al. VACCINE
- Recombinant Liver Stage Antigen-1 (LSA-1) formulated with AS01 or AS02 is safe, elicits high titer antibody and induces IFN-γ/IL-2 CD4+ T cells but does not protect against experimental Plasmodium falciparum infection
- (2009) James F. Cummings et al. VACCINE
- CD8+ T cell adjuvant effects of Salmonella FliCd flagellin in live vaccine vectors or as purified protein
- (2009) Catarina J.M. Braga et al. VACCINE
- Nanotechnology in vaccine delivery
- (2008) Laura J. Peek et al. ADVANCED DRUG DELIVERY REVIEWS
- TLR3: Interferon induction by double-stranded RNA including poly(I:C)☆
- (2008) M MATSUMOTO et al. ADVANCED DRUG DELIVERY REVIEWS
- Alum adjuvanticity: Unraveling a century old mystery
- (2008) Ennio De Gregorio et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The Nlrp3 inflammasome is critical for aluminium hydroxide-mediated IL-1β secretion but dispensable for adjuvant activity
- (2008) Luigi Franchi et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Safety and immunogenicity of a new hepatitis B vaccine for the protection of patients with renal insufficiency including pre-haemodialysis and haemodialysis patients
- (2008) Jiri Beran EXPERT OPINION ON BIOLOGICAL THERAPY
- Enhanced Immunogenicity of Plasmodium falciparum Peptide Vaccines Using a Topical Adjuvant Containing a Potent Synthetic Toll-Like Receptor 7 Agonist, Imiquimod
- (2008) C. Othoro et al. INFECTION AND IMMUNITY
- Poly(I:C) coated PLGA microparticles induce dendritic cell maturation
- (2008) C WISCHKE et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Alum adjuvant boosts adaptive immunity by inducing uric acid and activating inflammatory dendritic cells
- (2008) Mirjam Kool et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Crucial role for the Nalp3 inflammasome in the immunostimulatory properties of aluminium adjuvants
- (2008) Stephanie C. Eisenbarth et al. NATURE
- Efficacy of RTS,S/AS01E Vaccine against Malaria in Children 5 to 17 Months of Age
- (2008) Philip Bejon et al. NEW ENGLAND JOURNAL OF MEDICINE
- Phase I Trial of an Alhydrogel Adjuvanted Hepatitis B Core Virus-Like Particle Containing Epitopes of Plasmodium falciparum Circumsporozoite Protein
- (2008) Aric L. Gregson et al. PLoS One
- Evidence of Blood Stage Efficacy with a Virosomal Malaria Vaccine in a Phase IIa Clinical Trial
- (2008) Fiona M. Thompson et al. PLoS One
- Phase 1 Trial of Malaria Transmission Blocking Vaccine Candidates Pfs25 and Pvs25 Formulated with Montanide ISA 51
- (2008) Yimin Wu et al. PLoS One
- Genetic Immunisation by Liver Stage Antigen 3 Protects Chimpanzees against Malaria despite Low Immune Responses
- (2008) Pierre Daubersies et al. PLoS One
- Cationic Liposomes Formulated with Synthetic Mycobacterial Cordfactor (CAF01): A Versatile Adjuvant for Vaccines with Different Immunological Requirements
- (2008) Else Marie Agger et al. PLoS One
- Safety and Immunogenicity of a Recombinant Plasmodium falciparum AMA1 Malaria Vaccine Adjuvanted with Alhydrogel™, Montanide ISA 720 or AS02
- (2008) Meta Roestenberg et al. PLoS One
- Toll-like receptor ligands synergize through distinct dendritic cell pathways to induce T cell responses: Implications for vaccines
- (2008) Q. Zhu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- Influenza virosomes: a flu jab for malaria?
- (2008) David R. Cavanagh et al. TRENDS IN PARASITOLOGY
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- (2008) Amit Lahiri et al. VACCINE
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- (2008) Pascal Mettens et al. VACCINE
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- (2008) Alejandro Brun et al. VACCINE
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