Stat3 Upregulates Leucine-Rich Repeat-Containing G Protein-Coupled Receptor 4 Expression in Osteosarcoma Cells

GPR48, a poor prognostic factor, promotes tumor metastasis and activates β-catenin/TCF signaling in colorectal cancer

(2013) Jinhua Wu et al.   CARCINOGENESIS

Lgr4-mediated Wnt/ -catenin signaling in peritubular myoid cells is essential for spermatogenesis

(2013) Y. Qian et al.   DEVELOPMENT

Lgr4/Gpr48 Negatively Regulates TLR2/4-associated Pattern Recognition and Innate Immunity by Targeting CD14 Expression

(2013) Bing Du et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nonsense mutation in the LGR4 gene is associated with several human diseases and other traits

(2013) Unnur Styrkarsdottir et al.   NATURE

Lgr4 in Ocular Development and Glaucoma

(2013) Stefan Siwko et al.   Journal of Ophthalmology

S1PR1-STAT3 Signaling Is Crucial for Myeloid Cell Colonization at Future Metastatic Sites

(2012) Jiehui Deng et al.   CANCER CELL

STAT3 activation by IL-6 from mesenchymal stem cells promotes the proliferation and metastasis of osteosarcoma

(2012) Bing Tu et al.   CANCER LETTERS

STAT3 and EGFR target resistance

(2012) Rebecca Kirk   Nature Reviews Clinical Oncology

The complex world of WNT receptor signalling

(2012) Christof Niehrs   NATURE REVIEWS MOLECULAR CELL BIOLOGY

LGR4 and LGR5 are R-spondin receptors mediating Wnt/β-catenin and Wnt/PCP signalling

(2011) Andrei Glinka et al.   EMBO REPORTS

Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling

(2011) Wim de Lau et al.   NATURE

Conditional Knockout of Lgr4 Leads to Impaired Ductal Elongation and Branching Morphogenesis in Mouse Mammary Glands

(2011) K. Oyama et al.   Sexual Development

STAT3-induced S1PR1 expression is crucial for persistent STAT3 activation in tumors

(2010) Heehyoung Lee et al.   NATURE MEDICINE

Regulation of the IL-23 and IL-12 Balance by Stat3 Signaling in the Tumor Microenvironment

(2009) Marcin Kortylewski et al.   CANCER CELL

The JAK2 Inhibitor AZD1480 Potently Blocks Stat3 Signaling and Oncogenesis in Solid Tumors

(2009) Michael Hedvat et al.   CANCER CELL

Persistently Activated Stat3 Maintains Constitutive NF-κB Activity in Tumors

(2009) Heehyoung Lee et al.   CANCER CELL

G protein-coupled receptor 48 upregulates estrogen receptor   expression via cAMP/PKA signaling in the male reproductive tract

(2009) X.-Y. Li et al.   DEVELOPMENT

Regulation of bone formation and remodeling by G-protein-coupled receptor 48

(2009) J. Luo et al.   DEVELOPMENT

Impaired hair placode formation with reduced expression of hair follicle-related genes in mice lacking Lgr4

(2008) Yasuaki Mohri et al.   DEVELOPMENTAL DYNAMICS

Deletion of G protein-coupled receptor 48 leads to ocular anterior segment dysgenesis (ASD) through down-regulation of Pitx2

(2008) J. Weng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA