Biomaterial arrays with defined adhesion ligand densities and matrix stiffness identify distinct phenotypes for tumorigenic and non-tumorigenic human mesenchymal cell types

Wnt5a Directs Polarized Calcium Gradients by Recruiting Cortical Endoplasmic Reticulum to the Cell Trailing Edge

(2013) Eric S. Witze et al.   DEVELOPMENTAL CELL

Three-dimensional photolithographic micropatterning: a novel tool to probe the complexities of cell migration

(2013) Joseph C. Hoffmann et al.   Integrative Biology

Growth of confined cancer spheroids: a combined experimental and mathematical modelling approach

(2013) D. Loessner et al.   Integrative Biology

A Quantitative Comparison of Human HT-1080 Fibrosarcoma Cells and Primary Human Dermal Fibroblasts Identifies a 3D Migration Mechanism with Properties Unique to the Transformed Phenotype

(2013) Michael P. Schwartz et al.   PLoS One

Patterned Self-Assembled Monolayers: Efficient, Chemically Defined Tools for Cell Biology

(2012) Justin T. Koepsel et al.   CHEMBIOCHEM

Biophysical microenvironment and 3D culture physiological relevance

(2012) Amish Asthana et al.   DRUG DISCOVERY TODAY

A chemically-defined screening platform reveals behavioral similarities between primary human mesenchymal stem cells and endothelial cells

(2012) Justin T. Koepsel et al.   Integrative Biology

Differential effects of a soluble or immobilized VEGFR-binding peptide

(2012) Justin T. Koepsel et al.   Integrative Biology

Nonpolarized signaling reveals two distinct modes of 3D cell migration

(2012) Ryan J. Petrie et al.   JOURNAL OF CELL BIOLOGY

Combinatorial screening of chemically defined human mesenchymal stem cell culture substrates

(2012) Justin T. Koepsel et al.   JOURNAL OF MATERIALS CHEMISTRY

Bridging the Gap Between Physicochemistry and Interpretation Prevalent in Cell−Surface Interactions

(2011) Evan A. Dubiel et al.   CHEMICAL REVIEWS

Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer

(2011) T. R. Cox et al.   Disease Models & Mechanisms

Mechanical signaling through the cytoskeleton regulates cell proliferation by coordinated focal adhesion and Rho GTPase signaling

(2011) P. P. Provenzano et al.   JOURNAL OF CELL SCIENCE

Chemically well-defined self-assembled monolayers for cell culture: toward mimicking the natural ECM

(2011) Gregory A. Hudalla et al.   Soft Matter

An Inhibitor of a Cell Adhesion Receptor Stimulates Cell Migration

(2010) Shagufta H. Shabbir et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Bioengineered 3D platform to explore cell–ECM interactions and drug resistance of epithelial ovarian cancer cells

(2010) Daniela Loessner et al.   BIOMATERIALS

Cancer Cell Stiffness: Integrated Roles of Three-Dimensional Matrix Stiffness and Transforming Potential

(2010) Erin L. Baker et al.   BIOPHYSICAL JOURNAL

The plasticity of cytoskeletal dynamics underlying neoplastic cell migration

(2010) Victoria Sanz-Moreno et al.   CURRENT OPINION IN CELL BIOLOGY

Cancer Dissemination—Lessons from Leukocytes

(2010) Chris D. Madsen et al.   DEVELOPMENTAL CELL

Engineered 3D environments to elucidate the effect of environmental parameters on drug response in cancer

(2010) Maria Håkanson et al.   Integrative Biology

Transition to invasion in breast cancer: a microfluidic in vitro model enables examination of spatial and temporal effects

(2010) Kyung Eun Sung et al.   Integrative Biology

A distinctive role for focal adhesion proteins in three-dimensional cell motility

(2010) Stephanie I. Fraley et al.   NATURE CELL BIOLOGY

Can tissue engineering concepts advance tumor biology research?

(2010) Dietmar W. Hutmacher et al.   TRENDS IN BIOTECHNOLOGY

Using self-assembled monolayers to model the extracellular matrix

(2009) Milan Mrksich   Acta Biomaterialia

A Versatile Synthetic Extracellular Matrix Mimic via Thiol-Norbornene Photopolymerization

(2009) Benjamin D. Fairbanks et al.   ADVANCED MATERIALS

Elastic and adhesive properties of alkanethiol self-assembled monolayers on gold

(2009) Frank W. DelRio et al.   APPLIED PHYSICS LETTERS

Specific roles of Rac1 and Rac2 in motile functions of HT1080 fibrosarcoma cells

(2009) Verena Niggli et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The Mechanical Rigidity of the Extracellular Matrix Regulates the Structure, Motility, and Proliferation of Glioma Cells

(2009) T. A. Ulrich et al.   CANCER RESEARCH

Mechanical modes of ‘amoeboid’ cell migration

(2009) Tim Lämmermann et al.   CURRENT OPINION IN CELL BIOLOGY

A synthetic strategy for mimicking the extracellular matrix provides new insight about tumor cell migration

(2009) Michael P. Schwartz et al.   Integrative Biology

Protease-dependent versus -independent cancer cell invasion programs: three-dimensional amoeboid movement revisited

(2009) Farideh Sabeh et al.   JOURNAL OF CELL BIOLOGY

Matrix Architecture Dictates Three-Dimensional Migration Modes of Human Macrophages: Differential Involvement of Proteases and Podosome-Like Structures

(2009) E. Van Goethem et al.   JOURNAL OF IMMUNOLOGY

Patterning Discrete Stem Cell Culture Environments via Localized Self-Assembled Monolayer Replacement

(2009) Justin T. Koepsel et al.   LANGMUIR

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

(2009) D. E. Discher et al.   SCIENCE

Neutrophils display biphasic relationship between migration and substrate stiffness

(2009) Kimberly M. Stroka et al.   CELL MOTILITY AND THE CYTOSKELETON