Riluzole increases the rate of glucose transport in L6 myotubes and NSC-34 motor neuron-like cells via AMPK pathway activation

Nutrient deprivation induces the Warburg effect through ROS/AMPK-dependent activation of pyruvate dehydrogenase kinase

(2013) Ching-An Wu et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Thr649Ala-AS160 knock-in mutation does not impair contraction/AICAR-induced glucose transport in mouse muscle

(2012) Serge Ducommun et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Induction of mitochondrial uncoupling enhances VEGF120 but reduces MCP-1 release in mature 3T3-L1 adipocytes: Possible regulatory mechanism through endogenous ER stress and AMPK-related pathways

(2012) Kaoru Miyokawa-Gorin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

AMPK Activation by Dihydrotestosterone Reduces FSH-Stimulated Cell Proliferation in Rat Granulosa Cells by Inhibiting ERK Signaling Pathway

(2012) Pradeep P. Kayampilly et al.   ENDOCRINOLOGY

The Programming of Cardiac Hypertrophy in the Offspring by Maternal Obesity Is Associated with Hyperinsulinemia, AKT, ERK, and mTOR Activation

(2012) Denise S. Fernandez-Twinn et al.   ENDOCRINOLOGY

Activation of phosphatidylinositol-3 kinase, AMP-activated kinase and Akt substrate-160 kDa by trans-10, cis-12 conjugated linoleic acid mediates skeletal muscle glucose uptake

(2012) Suresh K. Mohankumar et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Tangeretin stimulates glucose uptake via regulation of AMPK signaling pathways in C2C12 myotubes and improves glucose tolerance in high-fat diet-induced obese mice

(2012) Myung Sunny Kim et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Exendin-4 Ameliorates Motor Neuron Degeneration in Cellular and Animal Models of Amyotrophic Lateral Sclerosis

(2012) Yazhou Li et al.   PLoS One

Caprylic Triglyceride as a Novel Therapeutic Approach to Effectively Improve the Performance and Attenuate the Symptoms Due to the Motor Neuron Loss in ALS Disease

(2012) Wei Zhao et al.   PLoS One

Chronic AMPK stimulation attenuates adaptive signaling in dystrophic skeletal muscle

(2011) Vladimir Ljubicic et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Brain hypermetabolism in amyotrophic lateral sclerosis: a FDG PET study in ALS of spinal and bulbar onset

(2011) Angelina Cistaro et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis

(2011) Arie Neymotin et al.   FREE RADICAL BIOLOGY AND MEDICINE

Antihyperglycaemic activity of 2,4:3,5-dibenzylidene-D-xylose-diethyl dithioacetal in diabetic mice

(2011) Arie Gruzman et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Early and Progressive Impairment of Spinal Blood Flow—Glucose Metabolism Coupling in Motor Neuron Degeneration of ALS Model Mice

(2011) Kazunori Miyazaki et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Recombinant human erythropoietin reduces aggregation of mutant Cu/Zn-binding superoxide dismutase (SOD1) in NSC-34 cells

(2011) Goang-Won Cho et al.   NEUROSCIENCE LETTERS

Patients with elevated triglyceride and cholesterol serum levels have a prolonged survival in amyotrophic lateral sclerosis

(2010) J. Dorst et al.   JOURNAL OF NEUROLOGY

Energy metabolism in amyotrophic lateral sclerosis

(2010) Luc Dupuis et al.   LANCET NEUROLOGY

Glucagon-like peptide-1 protects NSC-34 motor neurons against glucosamine through Epac-mediated glucose uptake enhancement

(2010) Jung-Geun Lim et al.   NEUROSCIENCE LETTERS

Mutant superoxide dismutase 1 overexpression in NSC-34 cells: Effect of trehalose on aggregation, TDP-43 localization and levels of co-expressed glycoproteins

(2010) Catarina Gomes et al.   NEUROSCIENCE LETTERS

Induction of Glucose Metabolism in Stimulated T Lymphocytes Is Regulated by Mitogen-Activated Protein Kinase Signaling

(2010) Aimee J. Marko et al.   PLoS One

Regulation of glucose transporter 4 traffic by energy deprivation from mitochondrial compromise

(2009) A. Klip et al.   Acta Physiologica

Riluzole protects Huntington disease patients from brain glucose hypometabolism and grey matter volume loss and increases production of neurotrophins

(2009) Ferdinando Squitieri et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

The role of AMP-activated protein kinase in the cardiovascular system

(2009) Daisuke Nagata et al.   HYPERTENSION RESEARCH

Transporters, channels, or simple diffusion? Dogmas, atypical roles and complexity in transport systems

(2009) Artur Conde et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A Novel Decoy That Interrupts G93A-Superoxide Dismutase Gain of Interaction with Malate Dehydrogenase Improves Survival in an Amyotrophic Lateral Sclerosis Cell Model

(2009) Yael Mali et al.   JOURNAL OF MEDICINAL CHEMISTRY

Inactivation of cytochromecoxidase by mutant SOD1s in mouse motoneuronal NSC-34 cells is independent from copper availability but is because of nitric oxide

(2009) Mario Arciello et al.   JOURNAL OF NEUROCHEMISTRY

VEGF up-regulation by G93A superoxide dismutase and the role of malate–aspartate shuttle inhibition

(2009) Yael Mali et al.   NEUROBIOLOGY OF DISEASE

The Human G93A-Superoxide Dismutase-1 Mutation, Mitochondrial Glutathione and Apoptotic Cell Death

(2009) H. Muyderman et al.   NEUROCHEMICAL RESEARCH

Riluzole protects against glutamate-induced slowing of neurofilament axonal transport

(2009) Alison Stevenson et al.   NEUROSCIENCE LETTERS

Characterization of Detergent-Insoluble Proteins in ALS Indicates a Causal Link between Nitrative Stress and Aggregation in Pathogenesis

(2009) Manuela Basso et al.   PLoS One

Preliminary quantitative profile of differential protein expression between rat L6 myoblasts and myotubes by stable isotope labeling with amino acids in cell culture

(2009) Ziyou Cui et al.   PROTEOMICS

Insulin action on glucose transporters through molecular switches, tracks and tethers

(2008) Hilal Zaid et al.   BIOCHEMICAL JOURNAL

Chronic Riluzole Treatment Increases Glucose Metabolism in Rat Prefrontal Cortex and Hippocampus

(2008) Golam MI Chowdhury et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Noveld-Xylose Derivatives Stimulate Muscle Glucose Uptake by Activating AMP-Activated Protein Kinase α

(2008) Arie Gruzman et al.   JOURNAL OF MEDICINAL CHEMISTRY

ALS drug development: Reflections from the past and a way forward

(2008) Swati Aggarwal et al.   Neurotherapeutics