The role of SON in splicing, development, and disease

Attenuation of AML1-ETO cellular dysregulation correlates with increased leukemogenic potential

(2013) R. C. DeKelver et al.   BLOOD

SON Protein Regulates GATA-2 through Transcriptional Control of the MicroRNA 23a∼27a∼24-2 Cluster

(2013) Erin Eun-Young Ahn et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

SON connects the splicing-regulatory network with pluripotency in human embryonic stem cells

(2013) Xinyi Lu et al.   NATURE CELL BIOLOGY

The interaction of the von Hippel-Lindau tumor suppressor and heterochromatin protein 1

(2012) Yanlai Lai et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The Cellular EJC Interactome Reveals Higher-Order mRNP Structure and an EJC-SR Protein Nexus

(2012) Guramrit Singh et al.   CELL

Perispeckles are major assembly sites for the exon junction core complex

(2012) Elisabeth Daguenet et al.   MOLECULAR BIOLOGY OF THE CELL

Targeting of MAPK-associated molecules identifies SON as a prime target to attenuate the proliferation and tumorigenicity of pancreatic cancer cells

(2012) Toru Furukawa et al.   Molecular Cancer

Structural bioinformatics of the human spliceosomal proteome

(2012) Iga Korneta et al.   NUCLEIC ACIDS RESEARCH

GC content around splice sites affects splicing through pre-mRNA secondary structures

(2011) Jing Zhang et al.   BMC GENOMICS

Son maintains accurate splicing for a subset of human pre-mRNAs

(2011) Alok Sharma et al.   JOURNAL OF CELL SCIENCE

SON Controls Cell-Cycle Progression by Coordinated Regulation of RNA Splicing

(2011) Eun-Young Ahn et al.   MOLECULAR CELL

Pre-mRNA splicing: where and when in the nucleus

(2011) Joonhee Han et al.   TRENDS IN CELL BIOLOGY

An Alternative Splicing Network Links Cell-Cycle Control to Apoptosis

(2010) Michael J. Moore et al.   CELL

SON is a spliceosome-associated factor required for mitotic progression

(2010) Michael S.Y. Huen et al.   CELL CYCLE

Son Is Essential for Nuclear Speckle Organization and Cell Cycle Progression

(2010) Alok Sharma et al.   MOLECULAR BIOLOGY OF THE CELL

The Nuclear-Retained Noncoding RNA MALAT1 Regulates Alternative Splicing by Modulating SR Splicing Factor Phosphorylation

(2010) Vidisha Tripathi et al.   MOLECULAR CELL

A genome-wide RNAi screen reveals determinants of human embryonic stem cell identity

(2010) Na-Yu Chia et al.   NATURE

Genome-wide RNAi screen identifies human host factors crucial for influenza virus replication

(2010) Alexander Karlas et al.   NATURE

Sequence-specific regulator Prdm14 safeguards mouse ESCs from entering extraembryonic endoderm fates

(2010) Ziyang Ma et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Nuclear Speckles

(2010) D. L. Spector et al.   Cold Spring Harbor Perspectives in Biology

Proteome analysis of human nuclear insoluble fractions

(2009) Hideaki Takata et al.   GENES TO CELLS

SR Proteins in Vertical Integration of Gene Expression from Transcription to RNA Processing to Translation

(2009) Xiang-Yang Zhong et al.   MOLECULAR CELL

An RNA code for the FOX2 splicing regulator revealed by mapping RNA-protein interactions in stem cells

(2009) Gene W Yeo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The SR protein family of splicing factors: master regulators of gene expression

(2008) Jennifer C. Long et al.   BIOCHEMICAL JOURNAL

HITS-CLIP yields genome-wide insights into brain alternative RNA processing

(2008) Donny D. Licatalosi et al.   NATURE

Disruption of the NHR4 domain structure in AML1-ETO abrogates SON binding and promotes leukemogenesis

(2008) E.-Y. Ahn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA