Virus-encoded endonucleases: expected and novel functions

The Herpes Simplex Virus Host Shutoff RNase Degrades Cellular and Viral mRNAs Made before Infection but Not Viral mRNA Made after Infection

(2013) B. Taddeo et al.   JOURNAL OF VIROLOGY

The Virion Host Shutoff RNase Plays a Key Role in Blocking the Activation of Protein Kinase R in Cells Infected with Herpes Simplex Virus 1

(2013) M. T. Sciortino et al.   JOURNAL OF VIROLOGY

Selective degradation of mRNAs by the HSV host shutoff RNase is regulated by the UL47 tegument protein

(2013) M. Shu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mRNA Decay during Herpes Simplex Virus (HSV) Infections: Mutations That Affect Translation of an mRNA Influence the Sites at Which It Is Cleaved by the HSV Virion Host Shutoff (Vhs) Protein

(2012) L. A. Shiflett et al.   JOURNAL OF VIROLOGY

Deletion of the Herpes Simplex Virus 1 UL49 Gene Results in mRNA and Protein Translation Defects That Are Complemented by Secondary Mutations in UL41

(2012) E. F. Mbong et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus Is Equipped with RNA- and Protein-Based Mechanisms To Repress Expression of ATRX, an Effector of Intrinsic Immunity

(2012) Igor Jurak et al.   JOURNAL OF VIROLOGY

A Common Strategy for Host RNA Degradation by Divergent Viruses

(2012) M. M. Gaglia et al.   JOURNAL OF VIROLOGY

Regulation of cytoplasmic mRNA decay

(2012) Daniel R. Schoenberg et al.   NATURE REVIEWS GENETICS

The eukaryotic initiation factor eIF4H facilitates loop-binding, repetitive RNA unwinding by the eIF4A DEAD-box helicase

(2012) Yingjie Sun et al.   NUCLEIC ACIDS RESEARCH

Emerging Therapeutics Targeting mRNA Translation

(2012) A. Malina et al.   Cold Spring Harbor Perspectives in Biology

The Virion Host Shutoff Protein of Herpes Simplex Virus 1 Blocks the Replication-Independent Activation of NF- B in Dendritic Cells in the Absence of Type I Interferon Signaling

(2011) C. R. Cotter et al.   JOURNAL OF VIROLOGY

The Herpes Simplex Virus 1 vhs Protein Enhances Translation of Viral True Late mRNAs and Virus Production in a Cell Type-Dependent Manner

(2011) B. Dauber et al.   JOURNAL OF VIROLOGY

mRNA helicases: the tacticians of translational control

(2011) Armen Parsyan et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Functional impairment of eIF4A and eIF4G factors correlates with inhibition of influenza virus mRNA translation

(2011) Emilio Yángüez et al.   VIROLOGY

Influenza virus polymerase confers independence of the cellular cap-binding factor eIF4E for viral mRNA translation

(2011) Emilio Yángüez et al.   VIROLOGY

So similar, yet so different: Selective translation of capped and polyadenylated viral mRNAs in the influenza virus infected cell

(2011) Emilio Yángüez et al.   VIRUS RESEARCH

Coordinated Destruction of Cellular Messages in Translation Complexes by the Gammaherpesvirus Host Shutoff Factor and the Mammalian Exonuclease Xrn1

(2011) Sergio Covarrubias et al.   PLoS Pathogens

Mechanisms of endonuclease-mediated mRNA decay

(2011) Daniel R. Schoenberg   Wiley Interdisciplinary Reviews-RNA

Role of Herpes Simplex Virus ICP27 in the Degradation of mRNA by Virion Host Shutoff RNase

(2010) B. Taddeo et al.   JOURNAL OF VIROLOGY

Evidence for Translational Regulation by the Herpes Simplex Virus Virion Host Shutoff Protein

(2010) H. A. Saffran et al.   JOURNAL OF VIROLOGY

The Virion Host Shutoff Endonuclease (UL41) of Herpes Simplex Virus Interacts with the Cellular Cap-Binding Complex eIF4F

(2010) H. G. Page et al.   JOURNAL OF VIROLOGY

Translational Regulation of Gene Expression during Conditions of Cell Stress

(2010) Keith A. Spriggs et al.   MOLECULAR CELL

The Virion Host Shut-Off (vhs) Protein Blocks a TLR-Independent Pathway of Herpes Simplex Virus Type 1 Recognition in Human and Mouse Dendritic Cells

(2010) Christopher R. Cotter et al.   PLoS One

Topology and Regulation of the Human eIF4A/4G/4H Helicase Complex in Translation Initiation

(2009) Assen Marintchev et al.   CELL

Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

(2009) Nahum Sonenberg et al.   CELL

Host Shutoff Is a Conserved Phenotype of Gammaherpesvirus Infection and Is Orchestrated Exclusively from the Cytoplasm

(2009) S. Covarrubias et al.   JOURNAL OF VIROLOGY

Many roads to maturity: microRNA biogenesis pathways and their regulation

(2009) Julia Winter et al.   NATURE CELL BIOLOGY

The virion-packaged endoribonuclease of herpes simplex virus 1 cleaves mRNA in polyribosomes

(2009) B. Taddeo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Selective Ablation of Virion Host Shutoff Protein RNase Activity Attenuates Herpes Simplex Virus 2 in Mice

(2008) M. Korom et al.   JOURNAL OF VIROLOGY

VP22 of Herpes Simplex Virus 1 Promotes Protein Synthesis at Late Times in Infection and Accumulation of a Subset of Viral mRNAs at Early Times in Infection

(2008) C. Duffy et al.   JOURNAL OF VIROLOGY

Small Interfering RNAs That Deplete the Cellular Translation Factor eIF4H Impede mRNA Degradation by the Virion Host Shutoff Protein of Herpes Simplex Virus

(2008) N. Sarma et al.   JOURNAL OF VIROLOGY

Herpes Simplex Virus Virion Host Shutoff Attenuates Establishment of the Antiviral State

(2008) T. J. Pasieka et al.   JOURNAL OF VIROLOGY

Selective Pharmacological Targeting of a DEAD Box RNA Helicase

(2008) Lisa Lindqvist et al.   PLoS One

Interactions between eIF4AI and its accessory factors eIF4B and eIF4H

(2008) N. Rozovsky et al.   RNA

Cap-dependent eukaryotic initiation factor-mRNA interactions probed by cross-linking

(2008) L. Lindqvist et al.   RNA

Re-programming of translation following cell stress allows IRES-mediated translation to predominate

(2007) Keith A. Spriggs et al.   BIOLOGY OF THE CELL