Mechanisms of endonuclease-mediated mRNA decay

Transcription factors Elk-1 and SRF are engaged in IL1-dependent regulation of ZC3H12A expression

(2010) Aneta Kasza et al.   BMC MOLECULAR BIOLOGY

SMG6 interacts with the exon junction complex via two conserved EJC-binding motifs (EBMs) required for nonsense-mediated mRNA decay

(2010) I. Kashima et al.   GENES & DEVELOPMENT

Diverse Endonucleolytic Cleavage Sites in the Mammalian Transcriptome Depend upon MicroRNAs, Drosha, and Additional Nucleases

(2010) Fedor V. Karginov et al.   MOLECULAR CELL

Expanding the MicroRNA Targeting Code: Functional Sites with Centered Pairing

(2010) Chanseok Shin et al.   MOLECULAR CELL

Identification of a consensus element recognized and cleaved by IRE1α

(2010) Daisuke Oikawa et al.   NUCLEIC ACIDS RESEARCH

No-go decay: a quality control mechanism for RNA in translation

(2010) Yuriko Harigaya et al.   Wiley Interdisciplinary Reviews-RNA

KSRP-PMR1-exosome association determines parathyroid hormone mRNA levels and stability in transfected cells

(2009) Morris Nechama et al.   BMC CELL BIOLOGY

IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates

(2009) Dan Han et al.   CELL

Interleukin-1-inducible MCPIP protein has structural and functional properties of RNase and participates in degradation of IL-1β mRNA

(2009) Danuta Mizgalska et al.   FEBS Journal

Stress-sensing mechanisms in the unfolded protein response: similarities and differences between yeast and mammals

(2009) K. Kohno   JOURNAL OF BIOCHEMISTRY

Regulated Ire1-dependent decay of messenger RNAs in mammalian cells

(2009) Julie Hollien et al.   JOURNAL OF CELL BIOLOGY

Analysis of Dom34 and Its Function in No-Go Decay

(2009) Dario O. Passos et al.   MOLECULAR BIOLOGY OF THE CELL

CRD-BP Protects the Coding Region of βTrCP1 mRNA from miR-183-Mediated Degradation

(2009) Irina Elcheva et al.   MOLECULAR CELL

Zc3h12a is an RNase essential for controlling immune responses by regulating mRNA decay

(2009) Kazufumi Matsushita et al.   NATURE

Identification of Apurinic/apyrimidinic endonuclease 1 (APE1) as the endoribonuclease that cleaves c-myc mRNA

(2009) T. Barnes et al.   NUCLEIC ACIDS RESEARCH

The N-terminal PIN domain of the exosome subunit Rrp44 harbors endonuclease activity and tethers Rrp44 to the yeast core exosome

(2009) Claudia Schneider et al.   NUCLEIC ACIDS RESEARCH

The cytoskeleton-associated Ena/VASP proteins are unanticipated partners of the PMR1 mRNA endonuclease

(2009) Y. Peng et al.   RNA

Transcriptional Regulatory Functions of Mammalian AP-Endonuclease (APE1/Ref-1), an Essential Multifunctional Protein

(2008) Kishor K. Bhakat et al.   ANTIOXIDANTS & REDOX SIGNALING

Early steps in the DNA base excision/single-strand interruption repair pathway in mammalian cells

(2008) Muralidhar L Hegde et al.   CELL RESEARCH

Messenger RNA regulation: to translate or to degrade

(2008) Ann-Bin Shyu et al.   EMBO JOURNAL

Endonucleolytic RNA cleavage by a eukaryotic exosome

(2008) Alice Lebreton et al.   NATURE

The multiple lives of NMD factors: balancing roles in gene and genome regulation

(2008) Olaf Isken et al.   NATURE REVIEWS GENETICS

SMG6 promotes endonucleolytic cleavage of nonsense mRNA in human cells

(2008) Andrea B Eberle et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities

(2008) Daneen Schaeffer et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Regulation of the human AP-endonuclease (APE1/Ref-1) expression by the tumor suppressor p53 in response to DNA damage

(2008) A. Zaky et al.   NUCLEIC ACIDS RESEARCH

SMG6 is the catalytic endonuclease that cleaves mRNAs containing nonsense codons in metazoan

(2008) E. Huntzinger et al.   RNA

The 90-kDa Heat Shock Protein Stabilizes the Polysomal Ribonuclease 1 mRNA Endonuclease to Degradation by the 26S Proteasome

(2007) Yong Peng et al.   MOLECULAR BIOLOGY OF THE CELL