Functional Consequences of Calcium Influx Promoted by Bacterial Pore-Forming Toxins

SERCA control of cell death and survival

(2018) Elie R. Chemaly et al.   CELL CALCIUM

Host cell perforation by listeriolysin O (LLO) activates a Ca2+-dependent cPKC/Rac1/Arp2/3 signaling pathway that promotes Listeria monocytogenes internalization independently of membrane resealing

(2018) Jonathan G. T. Lam et al.   MOLECULAR BIOLOGY OF THE CELL

Repair of a Bacterial Small β-Barrel Toxin Pore Depends on Channel Width

(2017) Gisela von Hoven et al.   mBio

Pseudomonas aeruginosa ExlA and Serratia marcescens ShlA trigger cadherin cleavage by promoting calcium influx and ADAM10 activation

(2017) Emeline Reboud et al.   PLoS Pathogens

Dissecting the role of ADAM10 as a mediator of Staphylococcus aureus  -toxin action

(2016) G. von Hoven et al.   BIOCHEMICAL JOURNAL

Active release of pneumolysin prepores and pores by mammalian cells undergoing a Streptococcus pneumoniae attack

(2016) Heidi Wolfmeier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Characterization of the Interactions between Calmodulin and Death Receptor 5 in Triple-negative and Estrogen Receptor-positive Breast Cancer Cells

(2016) Romone M. Fancy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Why Calcium? How Calcium Became the Best Communicator

(2016) Ernesto Carafoli et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Pneumolysin Mediates Platelet Activation In Vitro

(2016) Jan Gert Nel et al.   LUNG

Innate Immune Signaling Activated by MDR Bacteria in the Airway

(2016) Dane Parker et al.   PHYSIOLOGICAL REVIEWS

Ca2+-dependent repair of pneumolysin pores: A new paradigm for host cellular defense against bacterial pore-forming toxins

(2015) Heidi Wolfmeier et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Regulation of inflammasome activation

(2015) Si Ming Man et al.   IMMUNOLOGICAL REVIEWS

Pore-forming toxins: ancient, but never really out of fashion

(2015) Matteo Dal Peraro et al.   NATURE REVIEWS MICROBIOLOGY

Membrane Repair: Mechanisms and Pathophysiology

(2015) Sandra T. Cooper et al.   PHYSIOLOGICAL REVIEWS

Defying death: Cellular survival strategies following plasmalemmal injury by bacterial toxins

(2015) Eduard B. Babiychuk et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mitochondrial Ca2+-dependent NLRP3 activation exacerbates the Pseudomonas aeruginosa-driven inflammatory response in cystic fibrosis

(2015) Alessandro Rimessi et al.   Nature Communications

Necrosis: Linking the Inflammasome to Inflammation

(2015) Lorenzo Galluzzi et al.   Cell Reports

ESCRT Machinery Is Required for Plasma Membrane Repair

(2014) A. J. Jimenez et al.   SCIENCE

Molecular mechanisms of regulated necrosis

(2014) Lorenzo Galluzzi et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

The mitochondrial calcium uniporter complex: molecular components, structure and physiopathological implications

(2013) Saverio Marchi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Role of Pore-Forming Toxins in Bacterial Infectious Diseases

(2013) F. C. O. Los et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Cell targeting by the Staphylococcus aureus pore-forming toxins: it's not just about lipids

(2013) Ashley L. DuMont et al.   TRENDS IN MICROBIOLOGY

More Than a Pore: The Cellular Response to Cholesterol-Dependent Cytolysins

(2013) Sara Cassidy et al.   Toxins

Staphylococcal leukotoxins trigger free intracellular Ca2+rise in neurones, signalling through acidic stores and activation of store-operated channels

(2012) Emmanuel Jover et al.   CELLULAR MICROBIOLOGY

The Staphylococcus aureus Alpha-Toxin Perturbs the Barrier Function in Caco-2 Epithelial Cell Monolayers by Altering Junctional Integrity

(2012) Young-Keun Kwak et al.   INFECTION AND IMMUNITY

ADAM10 Mediates Vascular Injury Induced by Staphylococcus aureus α-Hemolysin

(2012) Michael E. Powers et al.   JOURNAL OF INFECTIOUS DISEASES

Critical role for calcium mobilization in activation of the NLRP3 inflammasome

(2012) T. Murakami et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Calcium Influx Rescues Adenylate Cyclase-Hemolysin from Rapid Cell Membrane Removal and Enables Phagocyte Permeabilization by Toxin Pores

(2012) Radovan Fiser et al.   PLoS Pathogens

Plasma membrane repair and cellular damage control: The annexin survival kit

(2011) Annette Draeger et al.   BIOCHEMICAL PHARMACOLOGY

RAB-5- and RAB-11-Dependent Vesicle-Trafficking Pathways Are Required for Plasma Membrane Repair after Attack by Bacterial Pore-Forming Toxin

(2011) Ferdinand C.O. Los et al.   Cell Host & Microbe

The role of ADAM-mediated shedding in vascular biology

(2011) Daniela Dreymueller et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Streptolysin O clearance through sequestration into blebs that bud passively from the plasma membrane

(2011) P. A. Keyel et al.   JOURNAL OF CELL SCIENCE

Aerolysin From Aeromonas hydrophila Perturbs Tight Junction Integrity and Cell Lesion Repair in Intestinal Epithelial HT-29/B6 Cells

(2011) Roland Bücker et al.   JOURNAL OF INFECTIOUS DISEASES

A Staphylococcus aureus pore-forming toxin subverts the activity of ADAM10 to cause lethal infection in mice

(2011) Ichiro Inoshima et al.   NATURE MEDICINE

Toxin Pores Endocytosed During Plasma Membrane Repair Traffic into the Lumen of MVBs for Degradation

(2011) Matthias Corrotte et al.   TRAFFIC

Global Functional Analyses of Cellular Responses to Pore-Forming Toxins

(2011) Cheng-Yuan Kao et al.   PLoS Pathogens

Intermedilysin induces EGR-1 expression through calcineurin/NFAT pathway in human cholangiocellular carcinoma cells

(2010) Heni Susilowati et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Blebbing confers resistance against cell lysis

(2010) E B Babiychuk et al.   CELL DEATH AND DIFFERENTIATION

Genetic control of necrosis—another type of programmed cell death

(2010) Kimberly McCall   CURRENT OPINION IN CELL BIOLOGY

TPCs: Endolysosomal channels for Ca2+ mobilization from acidic organelles triggered by NAADP

(2010) Michael X. Zhu et al.   FEBS LETTERS

The Ecto-enzyme CD38 Is a Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP) Synthase That Couples Receptor Activation to Ca2+Mobilization from Lysosomes in Pancreatic Acinar Cells

(2010) François Cosker et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of a disintegrin and metalloprotease 10 in Staphylococcus aureus  -hemolysin-mediated cellular injury

(2010) G. A. Wilke et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intracellular Ca2+ operates a switch between repair and lysis of streptolysin O-perforated cells

(2009) E B Babiychuk et al.   CELL DEATH AND DIFFERENTIATION

Membrane injury by pore-forming proteins

(2009) Mirko Bischofberger et al.   CURRENT OPINION IN CELL BIOLOGY

BordetellaAdenylate Cyclase Toxin Promotes Calcium Entry into Both CD11b+and CD11b−Cells through cAMP-dependent L-type-like Calcium Channels

(2009) César Martín et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Programmed Cellular Necrosis Mediated by the Pore-Forming α-Toxin from Clostridium septicum

(2009) Catherine L. Kennedy et al.   PLoS Pathogens

Effects of Staphylococcus aureus-hemolysin A on calcium signalling in immortalized human airway epithelial cells

(2008) Stefanie Eichstaedt et al.   CELL CALCIUM

Role of ADAMs in Endothelial Cell Permeability

(2008) Bharathy Ponnuchamy et al.   CIRCULATION RESEARCH

Repair of injured plasma membrane by rapid Ca2+-dependent endocytosis

(2008) Vincent Idone et al.   JOURNAL OF CELL BIOLOGY

The good, the bad and the ugly substrates for ADAM10 and ADAM17 in brain pathology, inflammation and cancer

(2008) Jessica Pruessmeyer et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Activation of the Unfolded Protein Response Is Required for Defenses against Bacterial Pore-Forming Toxin In Vivo

(2008) Larry J. Bischof et al.   PLoS Pathogens