Oncolytic Herpes Simplex Virus Counteracts the Hypoxia-Induced Modulation of Glioblastoma Stem-Like Cells

Regulation of G1 Arrest and Apoptosis in Hypoxia by PERK and GCN2-Mediated eIF2α Phosphorylation

(2015) Yan Liu et al.   NEOPLASIA

Hypoxia enhances the replication of oncolytic herpes simplex virus in p53- breast cancer cells

(2011) Michael Fasullo et al.   CELL CYCLE

A Novel Oncolytic Herpes Simplex Virus that Synergizes with Phosphoinositide 3-kinase/Akt Pathway Inhibitors to Target Glioblastoma Stem Cells

(2011) R. Kanai et al.   CLINICAL CANCER RESEARCH

Hypoxia Increases the Expression of Stem-Cell Markers and Promotes Clonogenicity in Glioblastoma Neurospheres

(2010) Eli E. Bar et al.   AMERICAN JOURNAL OF PATHOLOGY

A hypoxic niche regulates glioblastoma stem cells through hypoxia inducible factor 2α

(2010) Sascha Seidel et al.   BRAIN

Glioblastoma, Cancer Stem Cells and Hypoxia

(2010) Eli E. Bar   BRAIN PATHOLOGY

Hypoxia inducible factors in cancer stem cells

(2010) J M Heddleston et al.   BRITISH JOURNAL OF CANCER

Expression of the stem cell marker CD133 in recurrent glioblastoma and its value for prognosis

(2010) Roberto Pallini et al.   CANCER

A Hierarchy of Self-Renewing Tumor-Initiating Cell Types in Glioblastoma

(2010) Ruihuan Chen et al.   CANCER CELL

The hypoxic microenvironment maintains glioblastoma stem cells and promotes reprogramming towards a cancer stem cell phenotype

(2010) John M. Heddleston et al.   CELL CYCLE

Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche

(2010) Ahmed Mohyeldin et al.   Cell Stem Cell

Insight into the complex regulation of CD133 in glioma

(2010) Benito Campos et al.   INTERNATIONAL JOURNAL OF CANCER

Cancer Stem Cells: The Final Frontier for Glioma Virotherapy

(2010) Mahua Dey et al.   Stem Cell Reviews and Reports

Hypoxia-Inducible Factors Regulate Tumorigenic Capacity of Glioma Stem Cells

(2009) Zhizhong Li et al.   CANCER CELL

Human Glioblastoma-Derived Cancer Stem Cells: Establishment of Invasive Glioma Models and Treatment with Oncolytic Herpes Simplex Virus Vectors

(2009) H. Wakimoto et al.   CANCER RESEARCH

Hypoxia Helps Glioma to Fight Therapy

(2009) Verena Amberger-Murphy   CURRENT CANCER DRUG TARGETS

The role of oxygen in regulating neural stem cells in development and disease

(2009) David M. Panchision   JOURNAL OF CELLULAR PHYSIOLOGY

Tumor initiating cells in malignant gliomas: biology and implications for therapy

(2009) Costas G. Hadjipanayis et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Brain tumor hypoxia: tumorigenesis, angiogenesis, imaging, pseudoprogression, and as a therapeutic target

(2009) Randy L. Jensen   JOURNAL OF NEURO-ONCOLOGY

Hypoxia promotes expansion of the CD133-positive glioma stem cells through activation of HIF-1α

(2009) A Soeda et al.   ONCOGENE

Glioblastoma Formation from Cell Population Depleted of Prominin1-Expressing Cells

(2009) Kenji Nishide et al.   PLoS One

Neurosphere Formation Is an Independent Predictor of Clinical Outcome in Malignant Glioma

(2009) Dan R. Laks et al.   STEM CELLS

Proliferation of Human Glioblastoma Stem Cells Occurs Independently of Exogenous Mitogens

(2009) John J. P. Kelly et al.   STEM CELLS

CD133 Expression and Cancer Stem Cells Predict Prognosis in High-grade Oligodendroglial Tumors

(2008) Dagmar Beier et al.   BRAIN PATHOLOGY

Stem Cell Marker CD133 Affects Clinical Outcome in Glioma Patients

(2008) F. Zeppernick et al.   CLINICAL CANCER RESEARCH

Hypoxia induces protection against etoposide-induced apoptosis: molecular profiling of changes in gene expression and transcription factor activity

(2008) Audrey Sermeus et al.   Molecular Cancer

Hypoxia Enhances the Replication of Oncolytic Herpes Simplex Virus

(2008) Manish K Aghi et al.   MOLECULAR THERAPY

Phase Ib Trial of Mutant Herpes Simplex Virus G207 Inoculated Pre-and Post-tumor Resection for Recurrent GBM

(2008) James M Markert et al.   MOLECULAR THERAPY

Malignant Gliomas in Adults

(2008) Patrick Y. Wen et al.   NEW ENGLAND JOURNAL OF MEDICINE

CD133 Is a Marker of Bioenergetic Stress in Human Glioma

(2008) Corinne E. Griguer et al.   PLoS One