Heme Sensor Proteins

Structure and Regulation of Soluble Guanylate Cyclase

(2012) Emily R. Derbyshire et al.   Annual Review of Biochemistry

Environmental Heme-Based Sensor Proteins: Implications for Understanding Bacterial Pathogenesis

(2012) Aisha Farhana et al.   ANTIOXIDANTS & REDOX SIGNALING

How Do Heme-Protein Sensors Exclude Oxygen? Lessons Learned from Cytochrome c′, Nostoc puntiforme Heme Nitric Oxide/Oxygen-Binding Domain, and Soluble Guanylyl Cyclase

(2012) Ah-lim Tsai et al.   ANTIOXIDANTS & REDOX SIGNALING

Covalent Attachment of Heme to the Protein Moiety in an Insect E75 Nitric Oxide Sensor

(2012) Clara Aicart-Ramos et al.   BIOCHEMISTRY

Mechanisms of Mammalian Iron Homeostasis

(2012) Kostas Pantopoulos et al.   BIOCHEMISTRY

Mechanism of Binding of NO to Soluble Guanylyl Cyclase: Implication for the Second NO Binding to the Heme Proximal Site

(2012) Emil Martin et al.   BIOCHEMISTRY

Role of Cysteine Residues in Heme Binding to Human Heme Oxygenase-2 Elucidated by Two-dimensional NMR Spectroscopy

(2012) Fatbardha Varfaj et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PpsR, a Regulator of Heme and Bacteriochlorophyll Biosynthesis, Is a Heme-sensing Protein

(2012) Liang Yin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ferric, not ferrous, heme activates RNA-binding protein DGCR8 for primary microRNA processing

(2012) I. Barr et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stanniocalcin 1 binds hemin through a partially conserved heme regulatory motif

(2011) Johan A. Westberg et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DiGeorge Critical Region 8 (DGCR8) Is a Double-cysteine-ligated Heme Protein

(2011) Ian Barr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A novel insight into the heme and NO/CO binding mechanism of the alpha subunit of human soluble guanylate cyclase

(2011) Fangfang Zhong et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Effects of the bHLH domain on axial coordination of heme in the PAS-A domain of neuronal PAS domain protein 2 (NPAS2): Conversion from His119/Cys170 coordination to His119/His171 coordination

(2011) Takeshi Uchida et al.   JOURNAL OF INORGANIC BIOCHEMISTRY

Cysteine residue 911 in C-terminal tail of human BKCaα channel subunit is crucial for its activation by carbon monoxide

(2011) Vsevolod Telezhkin et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Direct Regulation of CLOCK Expression by REV-ERB

(2011) Christine Crumbley et al.   PLoS One

Soluble Guanylate Cyclase Is Activated Differently by Excess NO and by YC-1: Resonance Raman Spectroscopic Evidence

(2010) Mohammed Ibrahim et al.   BIOCHEMISTRY

Thiol-disulfide Redox Dependence of Heme Binding and Heme Ligand Switching in Nuclear Hormone Receptor Rev-erbβ

(2010) Nirupama Gupta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Identification of a Thiol/Disulfide Redox Switch in the Human BK Channel That Controls Its Affinity for Heme and CO

(2010) Li Yi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Spectroscopic insights into axial ligation and active-site H-bonding in substrate-bound human heme oxygenase-2

(2010) Jessica D. Gardner et al.   JOURNAL OF BIOLOGICAL INORGANIC CHEMISTRY

Hydrogen sulfide as a gasotransmitter

(2010) Moataz M. Gadalla et al.   JOURNAL OF NEUROCHEMISTRY

Nuclear ReceptorsHomo sapiensRev-erbβ andDrosophila melanogasterE75 Are Thiolate-Ligated Heme Proteins Which Undergo Redox-Mediated Ligand Switching and Bind CO and NO

(2009) Katherine A. Marvin et al.   BIOCHEMISTRY

Bacterial sensors of oxygen

(2009) Jeffrey Green et al.   CURRENT OPINION IN MICROBIOLOGY

Heme Regulatory Motifs in Heme Oxygenase-2 Form a Thiol/Disulfide Redox Switch That Responds to the Cellular Redox State

(2009) Li Yi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insight into the Heme-based Redox Sensing by DosS fromMycobacterium tuberculosis

(2009) Ha Yeon Cho et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A structural basis for H-NOX signaling in Shewanella oneidensis by trapping a histidine kinase inhibitory conformation

(2009) W. K. Erbil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Low-resolution structural studies of human Stanniocalcin-1

(2009) Daniel M Trindade et al.   BMC STRUCTURAL BIOLOGY

The Structural Basis of Gas-Responsive Transcription by the Human Nuclear Hormone Receptor REV-ERBβ

(2009) Keith I Pardee et al.   PLOS BIOLOGY

Arg97 at the Heme-Distal Side of the Isolated Heme-Bound PAS Domain of a Heme-Based Oxygen Sensor fromEscherichia coli(EcDOS) Plays Critical Roles in Autoxidation and Binding to Gases, Particularly O2†

(2008) Yukako Ishitsuka et al.   BIOCHEMISTRY

The Transcription Regulator RcoM-2 fromBurkholderia xenovoransIs a Cysteine-Ligated Hemoprotein That Undergoes a Redox-Mediated Ligand Switch†

(2008) Katherine A. Marvin et al.   BIOCHEMISTRY

Iron-dependent degradation of IRP2 requires its C-terminal region and IRP structural integrity

(2008) Jian Wang et al.   BMC MOLECULAR BIOLOGY

Cystathionine β-synthase as a carbon monoxide-sensitive regulator of bile excretion

(2008) Tsunehiro Shintani et al.   HEPATOLOGY

O2- and NO-Sensing Mechanism through the DevSR Two-Component System in Mycobacterium smegmatis

(2008) J.-M. Lee et al.   JOURNAL OF BACTERIOLOGY

Elucidation of the Heme Binding Site of Heme-regulated Eukaryotic Initiation Factor 2α Kinase and the Role of the Regulatory Motif in Heme Sensing by Spectroscopic and Catalytic Studies of Mutant Proteins

(2008) Jotaro Igarashi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A structural motif in the C-terminal tail of slo1 confers carbon monoxide sensitivity to human BKCa channels

(2008) Sandile E. Williams et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY