Salmonella Typhimurium effector SseI inhibits chemotaxis and increases host cell survival by deamidation of heterotrimeric Gi proteins

A module for Rac temporal signal integration revealed with optogenetics

(2017) Brian R. Graziano et al.   JOURNAL OF CELL BIOLOGY

Normal Thymocyte Egress, T Cell Trafficking, and CD4+T Cell Homeostasis Require Interactions between RGS Proteins and Gαi2

(2017) Il-Young Hwang et al.   JOURNAL OF IMMUNOLOGY

A second wave of Salmonella T3SS1 activity prolongs the lifespan of infected epithelial cells

(2017) Ciaran E. Finn et al.   PLoS Pathogens

Swiss Army Pathogen: The Salmonella Entry Toolkit

(2017) Peter J. Hume et al.   Frontiers in Cellular and Infection Microbiology

The impact of RGS and other G-protein regulatory proteins on Gαi-mediated signaling in immunity

(2016) John H. Kehrl   BIOCHEMICAL PHARMACOLOGY

Emerging Roles of Protein Deamidation in Innate Immune Signaling

(2016) Jun Zhao et al.   JOURNAL OF VIROLOGY

Inhibition of Nuclear Transport of NF-ĸB p65 by the Salmonella Type III Secretion System Effector SpvD

(2016) Nathalie Rolhion et al.   PLoS Pathogens

The biology of IQGAP proteins: beyond the cytoskeleton

(2015) A. C. Hedman et al.   EMBO REPORTS

Now you see me, now you don't: the interaction of Salmonella with innate immune receptors

(2015) A. Marijke Keestra-Gounder et al.   NATURE REVIEWS MICROBIOLOGY

Platelet Giprotein Gαi2is an essential mediator of thrombo-inflammatory organ damage in mice

(2015) Vasudharani Devanathan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

SseK3 Is a Salmonella Effector That Binds TRIM32 and Modulates the Host’s NF-κB Signalling Activity

(2015) Zhe Yang et al.   PLoS One

A microfluidic-based genetic screen to identify microbial virulence factors that inhibit dendritic cell migration

(2014) Laura M. McLaughlin et al.   Integrative Biology

A Chemical Biology Approach Demonstrates G Protein βγ Subunits Are Sufficient to Mediate Directional Neutrophil Chemotaxis

(2014) Chinmay R. Surve et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Noncanonical G-Protein-Dependent Modulation of Osteoclast Differentiation and Bone Resorption Mediated by Pasteurella multocida Toxin

(2014) Julia Strack et al.   mBio

Pasteurella multocida Toxin as a Transporter of Non-Cell-Permeating Proteins

(2013) Stefan Bergmann et al.   INFECTION AND IMMUNITY

Exploitation of eukaryotic subcellular targeting mechanisms by bacterial effectors

(2013) Stuart W. Hicks et al.   NATURE REVIEWS MICROBIOLOGY

Multiple Host Kinases Contribute to Akt Activation during Salmonella Infection

(2013) Bernhard Roppenser et al.   PLoS One

The Loss of Gnai2 and Gnai3 in B Cells Eliminates B Lymphocyte Compartments and Leads to a Hyper-IgM Like Syndrome

(2013) Il-Young Hwang et al.   PLoS One

Pasteurella Multocida Toxin Prevents Osteoblast Differentiation by Transactivation of the MAP-Kinase Cascade via the Gαq/11 - p63RhoGEF - RhoA Axis

(2013) Peter Siegert et al.   PLoS Pathogens

Structure of the catalytic domain of theSalmonellavirulence factor SseI

(2012) Shyam S. Bhaskaran et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Substrate specificity of Pasteurella multocida toxin for α subunits of heterotrimeric G proteins

(2012) Joachim H. C. Orth et al.   FASEB JOURNAL

Defective Macrophage Migration in G i2- but Not G i3-Deficient Mice

(2012) K. Wiege et al.   JOURNAL OF IMMUNOLOGY

Invasive non-typhoidal salmonella disease: an emerging and neglected tropical disease in Africa

(2012) Nicholas A Feasey et al.   LANCET

Enzymatic actions of Pasteurella multocida toxin detected by monoclonal antibodies recognizing the deamidated α subunit of the heterotrimeric GTPase Gq

(2011) Shigeki Kamitani et al.   FEBS Journal

Activation of Akt by the Bacterial Inositol Phosphatase, SopB, is Wortmannin Insensitive

(2011) Kendal G. Cooper et al.   PLoS One

Recent insights intoPasteurella multocidatoxin and other G-protein-modulating bacterial toxins

(2010) Brenda A Wilson et al.   Future Microbiology

Dendritic Cells Distinguish Individual Chemokine Signals through CCR7 and CXCR4

(2010) B. G. Ricart et al.   JOURNAL OF IMMUNOLOGY

Pasteurella multocida Toxin Activates Various Heterotrimeric G Proteins by Deamidation

(2010) Joachim H. C. Orth et al.   Toxins

Epidemic multiple drug resistant Salmonella Typhimurium causing invasive disease in sub-Saharan Africa have a distinct genotype

(2009) R. A. Kingsley et al.   GENOME RESEARCH

Pasteurella multocida toxin activation of heterotrimeric G proteins by deamidation

(2009) J. H. C. Orth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Salmonella SPI2 Effector SseI Mediates Long-Term Systemic Infection by Modulating Host Cell Migration

(2009) Laura M. McLaughlin et al.   PLoS Pathogens

Pasteurella multocida toxin activates Gβγ dimers of heterotrimeric G proteins

(2008) Inga Preuß et al.   CELLULAR SIGNALLING

Functional Analysis of the Salmonella Pathogenicity Island 2-Mediated Inhibition of Antigen Presentation in Dendritic Cells

(2008) S. Halici et al.   INFECTION AND IMMUNITY

How chemokines invite leukocytes to dance

(2008) Marcus Thelen et al.   NATURE IMMUNOLOGY

Staying alive: bacterial inhibition of apoptosis during infection

(2008) Christina S. Faherty et al.   TRENDS IN MICROBIOLOGY

Salmonellae interplay with host cells

(2007) Andrea Haraga et al.   NATURE REVIEWS MICROBIOLOGY