Critical role for cholesterol in Lassa fever virus entry identified by a novel small molecule inhibitor targeting the viral receptor LAMP1

TIM-1 Mediates Dystroglycan-Independent Entry of Lassa Virus

(2018) Rachel B. Brouillette et al.   JOURNAL OF VIROLOGY

Lamp1 Increases the Efficiency of Lassa Virus Infection by Promoting Fusion in Less Acidic Endosomal Compartments

(2018) Christine E. Hulseberg et al.   mBio

Axl Can Serve as Entry Factor for Lassa Virus Depending on the Functional Glycosylation of Dystroglycan

(2017) Chiara Fedeli et al.   JOURNAL OF VIROLOGY

Lysosome-associated membrane proteins-1 and -2 (LAMP-1 and LAMP-2) assemble via distinct modes

(2016) Kazue Terasawa et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Role of LAMP1 Binding and pH Sensing by the Spike Complex of Lassa Virus

(2016) Hadas Cohen-Dvashi et al.   JOURNAL OF VIROLOGY

Lassa Virus Cell Entry via Dystroglycan Involves an Unusual Pathway of Macropinocytosis

(2016) Joel Oppliger et al.   JOURNAL OF VIROLOGY

Acidic pH-Induced Conformations and LAMP1 Binding of the Lassa Virus Glycoprotein Spike

(2016) Sai Li et al.   PLoS Pathogens

Molecular Mechanism for LAMP1 Recognition by Lassa Virus

(2015) Hadas Cohen-Dvashi et al.   JOURNAL OF VIROLOGY

Thermal proteome profiling monitors ligand interactions with cellular membrane proteins

(2015) Friedrich B M Reinhard et al.   NATURE METHODS

The Phyre2 web portal for protein modeling, prediction and analysis

(2015) Lawrence A Kelley et al.   Nature Protocols

Haploid Genetic Screen Reveals a Profound and Direct Dependence on Cholesterol for Hantavirus Membrane Fusion

(2015) Lara M. Kleinfelter et al.   mBio

Lassa virus entry requires a trigger-induced receptor switch

(2014) L. T. Jae et al.   SCIENCE

Proteome-wide mapping of cholesterol-interacting proteins in mammalian cells

(2013) Jonathan J Hulce et al.   NATURE METHODS

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Crystal structure of the conserved domain of the DC lysosomal associated membrane protein: implications for the lysosomal glycocalyx

(2012) Sonja Wilke et al.   BMC BIOLOGY

Pathogenesis of Lassa Fever

(2012) Nadezhda E. Yun et al.   Viruses-Basel

Inhibition of Ebola Virus Infection: Identification of Niemann-Pick C1 as the Target by Optimization of a Chemical Probe

(2012) Kyungae Lee et al.   ACS Medicinal Chemistry Letters

Dispatched and Scube Mediate the Efficient Secretion of the Cholesterol-Modified Hedgehog Ligand

(2012) Hanna Tukachinsky et al.   Cell Reports

Identification of Cell Surface Molecules Involved in Dystroglycan-Independent Lassa Virus Cell Entry

(2011) M. Shimojima et al.   JOURNAL OF VIROLOGY

Small molecule inhibitors reveal Niemann–Pick C1 is essential for Ebola virus infection

(2011) Marceline Côté et al.   NATURE

SwissDock, a protein-small molecule docking web service based on EADock DSS

(2011) A. Grosdidier et al.   NUCLEIC ACIDS RESEARCH

Hepatitis B virus infection is dependent on cholesterol in the viral envelope

(2008) Corinna M. Bremer et al.   CELLULAR MICROBIOLOGY

Crimean-Congo hemorrhagic fever virus entry and replication is clathrin-, pH- and cholesterol-dependent

(2008) M. Simon et al.   JOURNAL OF GENERAL VIROLOGY