Glutamate Utilization Couples Oxidative Stress Defense and the Tricarboxylic Acid Cycle in Francisella Phagosomal Escape

Microbial quest for foodin vivo: ‘Nutritional virulence’ as an emerging paradigm

(2013) Yousef Abu Kwaik et al.   CELLULAR MICROBIOLOGY

Possible Links Between Stress Defense and the Tricarboxylic Acid (TCA) Cycle inFrancisellaPathogenesis

(2013) Jennifer Dieppedale et al.   MOLECULAR & CELLULAR PROTEOMICS

Type A Francisella tularensis Acid Phosphatases Contribute to Pathogenesis

(2013) Nrusingh P. Mohapatra et al.   PLoS One

Multifunctional essentiality of succinate metabolism in adaptation to hypoxia in Mycobacterium tuberculosis

(2013) H. Eoh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

GABA shunt mediates thermotolerance inSaccharomyces cerevisiaeby reducing reactive oxygen production

(2013) Juxiang Cao et al.   YEAST

Mechanisms of Francisella tularensis Intracellular Pathogenesis

(2013) J. Celli et al.   Cold Spring Harbor Perspectives in Medicine

Characterization of the Intracellular Glutamate Decarboxylase System: Analysis of Its Function, Transcription, and Role in the Acid Resistance of Various Strains of Listeria monocytogenes

(2012) Kimon-Andreas G. Karatzas et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Cytosolic clearance of replication-deficient mutants revealsFrancisella tularensisinteractions with the autophagic pathway

(2012) Audrey Chong et al.   Autophagy

AIM2/ASC triggers caspase-8-dependent apoptosis in Francisella-infected caspase-1-deficient macrophages

(2012) R Pierini et al.   CELL DEATH AND DIFFERENTIATION

Role of glutamate metabolism in bacterial responses towards acid and other stresses

(2012) C. Feehily et al.   JOURNAL OF APPLIED MICROBIOLOGY

Glutamate decarboxylase-dependent acid resistance in orally acquired bacteria: function, distribution and biomedical implications of thegadBCoperon

(2012) Daniela De Biase et al.   MOLECULAR MICROBIOLOGY

Structure and mechanism of a glutamate–GABA antiporter

(2012) Dan Ma et al.   NATURE

Link between intraphagosomal biotin and rapid phagosomal escape in Francisella

(2012) B. A. Napier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple Targets of Nitric Oxide in the Tricarboxylic Acid Cycle of Salmonella enterica Serovar Typhimurium

(2011) Anthony R. Richardson et al.   Cell Host & Microbe

Francisella Tularensis Metabolism and its Relation to Virulence

(2011) Karin Lederballe Meibom et al.   Frontiers in Microbiology

Innate Immune Recognition of Francisella Tularensis: Activation of Type-I Interferons and the Inflammasome

(2011) Jonathan Wiley Jones et al.   Frontiers in Microbiology

Intracellular Accumulation of High Levels of  -Aminobutyrate by Listeria monocytogenes 10403S in Response to Low pH: Uncoupling of  -Aminobutyrate Synthesis from Efflux in a Chemically Defined Medium

(2010) K. A. G. Karatzas et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Molecular bases of proliferation of Francisella tularensis in arthropod vectors

(2010) Rexford Asare et al.   ENVIRONMENTAL MICROBIOLOGY

Indoleamine 2,3-Dioxygenase 1 Is a Lung-Specific Innate Immune Defense Mechanism That Inhibits Growth of Francisella tularensis Tryptophan Auxotrophs

(2010) K. Peng et al.   INFECTION AND IMMUNITY

Francisella tularensisAntioxidants Harness Reactive Oxygen Species to Restrict Macrophage Signaling and Cytokine Production

(2010) Amanda A. Melillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Multiple mechanisms of NADPH oxidase inhibition by type A and type B Francisella tularensis

(2010) Ramona L. McCaffrey et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

(2010) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

(2010) Teresa Fernandes-Alnemri et al.   NATURE IMMUNOLOGY

Nucleolin, a Shuttle Protein Promoting Infection of Human Monocytes by Francisella tularensis

(2010) Monique Barel et al.   PLoS One

The unraveling panoply of Francisella tularensis virulence attributes

(2009) Karin L Meibom et al.   CURRENT OPINION IN MICROBIOLOGY

Francisella tularensis Phagosomal Escape Does Not Require Acidification of the Phagosome

(2009) D. L. Clemens et al.   INFECTION AND IMMUNITY

Identification of Francisella tularensis Live Vaccine Strain CuZn Superoxide Dismutase as Critical for Resistance to Extracellularly Generated Reactive Oxygen Species

(2009) A. A. Melillo et al.   JOURNAL OF BACTERIOLOGY

Glutathione Provides a Source of Cysteine Essential for Intracellular Multiplication of Francisella tularensis

(2009) Khaled Alkhuder et al.   PLoS Pathogens

Genome-Wide Screen in Francisella novicida for Genes Required for Pulmonary and Systemic Infection in Mice

(2008) P. S. Kraemer et al.   INFECTION AND IMMUNITY

Combined Deletion of Four Francisella novicida Acid Phosphatases Attenuates Virulence and Macrophage Vacuolar Escape

(2008) N. P. Mohapatra et al.   INFECTION AND IMMUNITY

Acquisition of the Vacuolar ATPase Proton Pump and Phagosome Acidification Are Essential for Escape of Francisella tularensis into the Macrophage Cytosol

(2008) M. Santic et al.   INFECTION AND IMMUNITY