Host Cell Invasion by Apicomplexan Parasites: The Junction Conundrum

Conditional expression of apical membrane antigen 1 inPlasmodium falciparumshows it is required for erythrocyte invasion by merozoites

(2014) Alan Yap et al.   CELLULAR MICROBIOLOGY

The Toxoplasma Acto-MyoA Motor Complex Is Important but Not Essential for Gliding Motility and Host Cell Invasion

(2014) Saskia Egarter et al.   PLoS One

Toxoplasmaaldolase is required for metabolism but dispensable for host-cell invasion

(2014) Bang Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasticity and redundancy among AMA–RON pairs ensure host cell entry of Toxoplasma parasites

(2014) Mauld H. Lamarque et al.   Nature Communications

RON5 Is Critical for Organization and Function of the Toxoplasma Moving Junction Complex

(2014) Josh R. Beck et al.   PLoS Pathogens

RALP1 Is a Rhoptry Neck Erythrocyte-Binding Protein of Plasmodium falciparum Merozoites and a Potential Blood-Stage Vaccine Candidate Antigen

(2013) Daisuke Ito et al.   INFECTION AND IMMUNITY

The cytoplasm of living cells behaves as a poroelastic material

(2013) Emad Moeendarbary et al.   NATURE MATERIALS

Malaria biology and disease pathogenesis: insights for new treatments

(2013) Louis H Miller et al.   NATURE MEDICINE

Toxoplasma gondii Sporozoites Invade Host Cells Using Two Novel Paralogues of RON2 and AMA1

(2013) Anna Poukchanski et al.   PLoS One

Extended Safety, Immunogenicity and Efficacy of a Blood-Stage Malaria Vaccine in Malian Children: 24-Month Follow-Up of a Randomized, Double-Blinded Phase 2 Trial

(2013) Matthew B. Laurens et al.   PLoS One

Disrupting malaria parasite AMA1–RON2 interaction with a small molecule prevents erythrocyte invasion

(2013) Prakash Srinivasan et al.   Nature Communications

Apical membrane antigen 1 mediates apicomplexan parasite attachment but is dispensable for host cell invasion

(2013) Daniel Y. Bargieri et al.   Nature Communications

Characterization of the interaction between Toxoplasma gondii rhoptry neck protein 4 and host cellular β-tubulin

(2013) Hitoshi Takemae et al.   Scientific Reports

Tunable Substrates Unveil Chemical Complementation of a Genetic Cell Migration Defect

(2013) Janina Kristin Hellmann et al.   Advanced Healthcare Materials

Toxoplasma gondii Profilin Acts Primarily To Sequester G-Actin While Formins Efficiently Nucleate Actin Filament Formation in Vitro

(2012) Kristen M. Skillman et al.   BIOCHEMISTRY

The role of the reticulocyte-binding-like protein homologues ofPlasmodiumin erythrocyte sensing and invasion

(2012) Karthigayan Gunalan et al.   CELLULAR MICROBIOLOGY

The moving junction, a key portal to host cell invasion by apicomplexan parasites

(2012) Bang Shen et al.   CURRENT OPINION IN MICROBIOLOGY

Toxofilin upregulates the host cortical actin cytoskeleton dynamics, facilitating Toxoplasma invasion

(2012) V. Delorme-Walker et al.   JOURNAL OF CELL SCIENCE

Conditional genome engineering in Toxoplasma gondii uncovers alternative invasion mechanisms

(2012) Nicole Andenmatten et al.   NATURE METHODS

Spatial Localisation of Actin Filaments across Developmental Stages of the Malaria Parasite

(2012) Fiona Angrisano et al.   PLoS One

Shape change in the receptor for gliding motility in Plasmodium sporozoites

(2012) G. Song et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Intramembrane proteolysis of Toxoplasma apical membrane antigen 1 facilitates host-cell invasion but is dispensable for replication

(2012) F. Parussini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural and Functional Insights into the Malaria Parasite Moving Junction Complex

(2012) Brigitte Vulliez-Le Normand et al.   PLoS Pathogens

Super-Resolution Dissection of Coordinated Events during Malaria Parasite Invasion of the Human Erythrocyte

(2011) David T. Riglar et al.   Cell Host & Microbe

Independent Roles of Apical Membrane Antigen 1 and Rhoptry Neck Proteins during Host Cell Invasion by Apicomplexa

(2011) Donatella Giovannini et al.   Cell Host & Microbe

Apical Membrane Antigen 1 as an Anti-Malarial Drug Target

(2011) Christopher A. MacRaild et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

A Toxoplasma gondii protein with homology to intracellular type Na+/H+ exchangers is important for osmoregulation and invasion

(2011) Maria E. Francia et al.   EXPERIMENTAL CELL RESEARCH

Differences in Erythrocyte Receptor Specificity of Different Parts of the Plasmodium falciparum Reticulocyte Binding Protein Homologue 2a

(2011) Karthigayan Gunalan et al.   INFECTION AND IMMUNITY

Vital functions of the malarial ookinete protein, CTRP, reside in the A domains

(2011) Chandra Ramakrishnan et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Actin depolymerizing factor controls actin turnover and gliding motility in Toxoplasma gondii

(2011) Simren Mehta et al.   MOLECULAR BIOLOGY OF THE CELL

Binding ofPlasmodiummerozoite proteins RON2 and AMA1 triggers commitment to invasion

(2011) Prakash Srinivasan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Revealing a Parasite's Invasive Trick

(2011) J. Baum et al.   SCIENCE

Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of AMA1 with a RON2 Peptide

(2011) M. L. Tonkin et al.   SCIENCE

Juxtamembrane Shedding of Plasmodium falciparum AMA1 Is Sequence Independent and Essential, and Helps Evade Invasion-Inhibitory Antibodies

(2011) Anna Olivieri et al.   PLoS Pathogens

Evolutionarily Divergent, Unstable Filamentous Actin Is Essential for Gliding Motility in Apicomplexan Parasites

(2011) Kristen M. Skillman et al.   PLoS Pathogens

The RON2-AMA1 Interaction is a Critical Step in Moving Junction-Dependent Invasion by Apicomplexan Parasites

(2011) Mauld Lamarque et al.   PLoS Pathogens

The C-Terminus of Toxoplasma RON2 Provides the Crucial Link between AMA1 and the Host-Associated Invasion Complex

(2011) Jessica S. Tyler et al.   PLoS Pathogens

Functional Dissection of the Apicomplexan Glideosome Molecular Architecture

(2010) Karine Frénal et al.   Cell Host & Microbe

Interaction betweenPlasmodium falciparumApical Membrane Antigen 1 and the Rhoptry Neck Protein Complex Defines a Key Step in the Erythrocyte Invasion Process of Malaria Parasites

(2010) Dave Richard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Concerted Action of Two Formins in Gliding Motility and Host Cell Invasion by Toxoplasma gondii

(2010) Wassim Daher et al.   PLoS Pathogens

Clonal Conditional Mutagenesis in Malaria Parasites

(2009) Audrey Combe et al.   Cell Host & Microbe

Plasmodium Sporozoite Motility Is Modulated by the Turnover of Discrete Adhesion Sites

(2009) Sylvia Münter et al.   Cell Host & Microbe

Host Cell Entry by Apicomplexa Parasites Requires Actin Polymerization in the Host Cell

(2009) Virginie Gonzalez et al.   Cell Host & Microbe

Aldolase Is Essential for Energy Production and Bridging Adhesin-Actin Cytoskeletal Interactions during Parasite Invasion of Host Cells

(2009) G. Lucas Starnes et al.   Cell Host & Microbe

Toxoplasma gondii Actin Depolymerizing Factor Acts Primarily to Sequester G-actin

(2009) Simren Mehta et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intracellular fluid flow in rapidly moving cells

(2009) Kinneret Keren et al.   NATURE CELL BIOLOGY

An Inhibitory Antibody Blocks Interactions between Components of the Malarial Invasion Machinery

(2009) Christine R. Collins et al.   PLoS Pathogens

Export of a Toxoplasma gondii Rhoptry Neck Protein Complex at the Host Cell Membrane to Form the Moving Junction during Invasion

(2009) Sébastien Besteiro et al.   PLoS Pathogens

A Malaria Parasite Formin Regulates Actin Polymerization and Localizes to the Parasite-Erythrocyte Moving Junction during Invasion

(2008) Jake Baum et al.   Cell Host & Microbe

Toxoplasma Profilin Is Essential for Host Cell Invasion and TLR11-Dependent Induction of an Interleukin-12 Response

(2008) Fabienne Plattner et al.   Cell Host & Microbe

Novel components of the Apicomplexan moving junction reveal conserved and coccidia-restricted elements

(2008) Kurtis W. Straub et al.   CELLULAR MICROBIOLOGY

GAP45 Phosphorylation Controls Assembly of theToxoplasmaMyosin XIV Complex

(2008) Stacey D. Gilk et al.   EUKARYOTIC CELL

Identification and Characterization of the Plasmodium yoelii PyP140/RON4 Protein, an Orthologue of Toxoplasma gondii RON4, Whose Cysteine-Rich Domain Does Not Protect against Lethal Parasite Challenge Infection

(2008) D. L. Narum et al.   INFECTION AND IMMUNITY

Reticulocyte-binding protein homologue 5 – An essential adhesin involved in invasion of human erythrocytes by Plasmodium falciparum

(2008) Jake Baum et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Microneme protein 8 - a new essential invasion factor in Toxoplasma gondii

(2008) H. Kessler et al.   JOURNAL OF CELL SCIENCE

The Transmembrane Isoform of Plasmodium falciparum MAEBL Is Essential for the Invasion of Anopheles Salivary Glands

(2008) Fabian E. Saenz et al.   PLoS One

Implications of a poroelastic cytoplasm for the dynamics of animal cell shape

(2008) T.J. Mitchison et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Apical membrane antigen 1: a malaria vaccine candidate in review

(2008) Edmond J. Remarque et al.   TRENDS IN PARASITOLOGY

No TRAP, no invasion

(2008) Belinda J. Morahan et al.   TRENDS IN PARASITOLOGY

Host Cell Egress and Invasion Induce Marked Relocations of Glycolytic Enzymes in Toxoplasma gondii Tachyzoites

(2008) Sebastien Pomel et al.   PLoS Pathogens

Cryptosporidia: Epicellular parasites embraced by the host cell membrane

(2007) Andrea Valigurová et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY