Juxtamembrane Shedding of Plasmodium falciparum AMA1 Is Sequence Independent and Essential, and Helps Evade Invasion-Inhibitory Antibodies

Molecular dissection of host cell invasion by the Apicomplexans: the glideosome

(2013) D. Soldati-Favre   Parasite

Global Identification of Multiple Substrates forPlasmodium falciparumSUB1, an Essential Malarial Processing Protease

(2011) Natalie C. Silmon de Monerri et al.   INFECTION AND IMMUNITY

Host Cell Invasion by Apicomplexan Parasites: Insights from the Co-Structure of AMA1 with a RON2 Peptide

(2011) M. L. Tonkin et al.   SCIENCE

The RON2-AMA1 Interaction is a Critical Step in Moving Junction-Dependent Invasion by Apicomplexan Parasites

(2011) Mauld Lamarque et al.   PLoS Pathogens

The C-Terminus of Toxoplasma RON2 Provides the Crucial Link between AMA1 and the Host-Associated Invasion Complex

(2011) Jessica S. Tyler et al.   PLoS Pathogens

Taking the plunge: integrating structural, enzymatic and computational insights into a unified model for membrane-immersed rhomboid proteolysis

(2010) Sinisa Urban   BIOCHEMICAL JOURNAL

Interaction betweenPlasmodium falciparumApical Membrane Antigen 1 and the Rhoptry Neck Protein Complex Defines a Key Step in the Erythrocyte Invasion Process of Malaria Parasites

(2010) Dave Richard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Antibodies against multiple merozoite surface antigens of the human malaria parasite Plasmodium falciparum inhibit parasite maturation and red blood cell invasion

(2010) Ute Woehlbier et al.   MALARIA JOURNAL

Intramembrane Cleavage of AMA1 Triggers Toxoplasma to Switch from an Invasive to a Replicative Mode

(2010) J. M. Santos et al.   SCIENCE

Rhomboid 4 (ROM4) Affects the Processing of Surface Adhesins and Facilitates Host Cell Invasion by Toxoplasma gondii

(2010) Jeffrey S. Buguliskis et al.   PLoS Pathogens

Protein Kinase A Dependent Phosphorylation of Apical Membrane Antigen 1 Plays an Important Role in Erythrocyte Invasion by the Malaria Parasite

(2010) Kerstin Leykauf et al.   PLoS Pathogens

Two Mosquito LRR Proteins Function as Complement Control Factors in the TEP1-Mediated Killing of Plasmodium

(2009) Malou Fraiture et al.   Cell Host & Microbe

Clonal Conditional Mutagenesis in Malaria Parasites

(2009) Audrey Combe et al.   Cell Host & Microbe

Anti-Apical-Membrane-Antigen-1 Antibody Is More Effective than Anti-42-Kilodalton-Merozoite-Surface-Protein-1 Antibody in Inhibiting Plasmodium falciparum Growth, as Determined by the In Vitro Growth Inhibition Assay

(2009) K. Miura et al.   Clinical and Vaccine Immunology

Rapid Optimization of a Peptide Inhibitor of Malaria Parasite Invasion by ComprehensiveN-Methyl Scanning

(2009) Karen S. Harris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sequence-Specific Intramembrane Proteolysis: Identification of a Recognition Motif in Rhomboid Substrates

(2009) Kvido Strisovsky et al.   MOLECULAR CELL

The carboxy-terminus of merozoite surface protein 1: structure, specific antibodies and immunity to malaria

(2009) A. A. HOLDER   PARASITOLOGY

Blood Stage Malaria Vaccine Eliciting High Antigen-Specific Antibody Concentrations Confers No Protection to Young Children in Western Kenya

(2009) Bernhards R. Ogutu et al.   PLoS One

Phase 1/2a Study of the Malaria Vaccine Candidate Apical Membrane Antigen-1 (AMA-1) Administered in Adjuvant System AS01B or AS02A

(2009) Michele D. Spring et al.   PLoS One

A randomized controlled phase 2 trial of the blood stage AMA1-C1/Alhydrogel malaria vaccine in children in Mali

(2009) Issaka Sagara et al.   VACCINE

Functional Analysis of the Leading Malaria Vaccine Candidate AMA-1 Reveals an Essential Role for the Cytoplasmic Domain in the Invasion Process

(2009) Moritz Treeck et al.   PLoS Pathogens

An Inhibitory Antibody Blocks Interactions between Components of the Malarial Invasion Machinery

(2009) Christine R. Collins et al.   PLoS Pathogens

Morphology and kinetics of the three distinct phases of red blood cell invasion by Plasmodium falciparum merozoites

(2008) Paul R. Gilson et al.   INTERNATIONAL JOURNAL FOR PARASITOLOGY

Evidence of Blood Stage Efficacy with a Virosomal Malaria Vaccine in a Phase IIa Clinical Trial

(2008) Fiona M. Thompson et al.   PLoS One

Safety and Immunogenicity of a Recombinant Plasmodium falciparum AMA1 Malaria Vaccine Adjuvanted with Alhydrogel™, Montanide ISA 720 or AS02

(2008) Meta Roestenberg et al.   PLoS One

Apical membrane antigen 1: a malaria vaccine candidate in review

(2008) Edmond J. Remarque et al.   TRENDS IN PARASITOLOGY

Recent insights into humoral and cellular immune responses against malaria

(2008) James G. Beeson et al.   TRENDS IN PARASITOLOGY