The CD27L and CTP1L Endolysins Targeting Clostridia Contain a Built-in Trigger and Release Factor

Evaluation of bacteriophage therapy to control Clostridium difficile and toxin production in an in vitro human colon model system

(2013) Emma Meader et al.   ANAEROBE

Gut solutions to a gut problem: bacteriocins, probiotics and bacteriophage for control of Clostridium difficile infection

(2013) M. C. Rea et al.   JOURNAL OF MEDICAL MICROBIOLOGY

Completion of autobuilt protein models using a database of protein fragments

(2012) Kevin Cowtan   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Allostery and the Monod-Wyman-Changeux Model After 50 Years

(2012) Jean-Pierre Changeux   Annual Review of Biophysics

Genomic Sequence of Bacteriophage ATCC 8074-B1 and Activity of Its Endolysin and Engineered Variants against Clostridium sporogenes

(2012) Melinda J. Mayer et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Current State of Clostridium difficile Treatment Options

(2012) A. A. Venugopal et al.   CLINICAL INFECTIOUS DISEASES

New developments in theATSASprogram package for small-angle scattering data analysis

(2012) Maxim V. Petoukhov et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Insights into cis-autoproteolysis reveal a reactive state formed through conformational rearrangement

(2012) A. R. Buller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

X-ray crystal structure of the streptococcal specific phage lysin PlyC

(2012) S. McGowan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tools from viruses: Bacteriophage successes and beyond

(2012) Marine Henry et al.   VIROLOGY

Macromolecular complexes in crystals and solutions

(2011) Evgeny Krissinel   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

REFMAC5 for the refinement of macromolecular crystal structures

(2011) Garib N. Murshudov et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

A stable phage lysin (Cpl-1) dimer with increased antipneumococcal activity and decreased plasma clearance

(2011) Gregory Resch et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Structure-Based Modification of a Clostridium difficile-Targeting Endolysin Affects Activity and Host Range

(2011) M. J. Mayer et al.   JOURNAL OF BACTERIOLOGY

Role of Net Charge on Catalytic Domain and Influence of Cell Wall Binding Domain on Bactericidal Activity, Specificity, and Host Range of Phage Lysins

(2011) Lieh Yoon Low et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Genomic Sequence and Characterization of the Virulent Bacteriophage  CTP1 from Clostridium tyrobutyricum and Heterologous Expression of Its Endolysin

(2010) M. J. Mayer et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Holin triggering in real time

(2010) R. White et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Micron-scale holes terminate the phage infection cycle

(2010) J. S. Dewey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular replacement withMOLREP

(2009) Alexei Vagin et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

DAMMIF, a program for rapidab-initioshape determination in small-angle scattering

(2009) Daniel Franke et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Crystallographic Insights into the Autocatalytic Assembly Mechanism of a Bacteriophage Tail Spike

(2009) Ye Xiang et al.   MOLECULAR CELL

Molecular Characterization of a Clostridium difficile Bacteriophage and Its Cloned Biologically Active Endolysin

(2008) M. J. Mayer et al.   JOURNAL OF BACTERIOLOGY