Papillomavirus Genomes Associate with BRD4 to Replicate at Fragile Sites in the Host Genome

Selective Inhibition of Tumor Oncogenes by Disruption of Super-Enhancers

(2013) Jakob Lovén et al.   CELL

Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes

(2013) Warren A. Whyte et al.   CELL

Genome-wide analysis of HPV integration in human cancers reveals recurrent, focal genomic instability

(2013) K. Akagi et al.   GENOME RESEARCH

Preferential sites for the integration and disruption of human papillomavirus 16 in cervical lesions

(2013) Hui Li et al.   JOURNAL OF CLINICAL VIROLOGY

Recruitment of Brd4 to the Human Papillomavirus Type 16 DNA Replication Complex Is Essential for Replication of Viral DNA

(2013) X. Wang et al.   JOURNAL OF VIROLOGY

FANCD2 Binds MCM Proteins and Controls Replisome Function upon Activation of S Phase Checkpoint Signaling

(2013) Gérald Lossaint et al.   MOLECULAR CELL

The bromodomain protein Brd4 insulates chromatin from DNA damage signalling

(2013) Scott R. Floyd et al.   NATURE

Multiplex Identification of Human Papillomavirus 16 DNA Integration Sites in Cervical Carcinomas

(2013) Bo Xu et al.   PLoS One

The Papillomavirus E2 proteins

(2013) Alison A. McBride   VIROLOGY

Current Understanding of the Role of the Brd4 Protein in the Papillomavirus Lifecycle

(2013) Alison McBride et al.   Viruses-Basel

Common Fragile Site Profiling in Epithelial and Erythroid Cells Reveals that Most Recurrent Cancer Deletions Lie in Fragile Sites Hosting Large Genes

(2013) Benoît Le Tallec et al.   Cell Reports

Brd4 Is Displaced from HPV Replication Factories as They Expand and Amplify Viral DNA

(2013) Nozomi Sakakibara et al.   PLoS Pathogens

Papillomaviruses Use Recombination-Dependent Replication to Vegetatively Amplify Their Genomes in Differentiated Cells

(2013) Nozomi Sakakibara et al.   PLoS Pathogens

A genome-wide analysis of common fragile sites: What features determine chromosomal instability in the human genome?

(2012) Arkarachai Fungtammasan et al.   GENOME RESEARCH

Human Papillomaviruses Recruit Cellular DNA Repair and Homologous Recombination Factors to Viral Replication Centers

(2012) K. A. Gillespie et al.   JOURNAL OF VIROLOGY

Differential gene and transcript expression analysis of RNA-seq experiments with TopHat and Cufflinks

(2012) Cole Trapnell et al.   Nature Protocols

The Papillomavirus Episteme: a central resource for papillomavirus sequence data and analysis

(2012) Koenraad Van Doorslaer et al.   NUCLEIC ACIDS RESEARCH

HPV Genotyping and Site of Viral Integration in Cervical Cancers in Indian Women

(2012) Poulami Das et al.   PLoS One

Exploring Massive, Genome Scale Datasets with the GenometriCorr Package

(2012) Alexander Favorov et al.   PLoS Computational Biology

BET Bromodomain Inhibition as a Therapeutic Strategy to Target c-Myc

(2011) Jake E. Delmore et al.   CELL

Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development

(2011) Assaf C. Bester et al.   CELL

Human Papillomavirus (HPV)E7Induces Prolonged G2following S Phase Reentry in Differentiated Human Keratinocytes

(2011) N. Sanjib Banerjee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Papillomavirus E1 Helicase Activates a Cellular DNA Damage Response in Viral Replication Foci

(2011) N. Sakakibara et al.   JOURNAL OF VIROLOGY

Nuclear Accumulation of the Papillomavirus E1 Helicase Blocks S-Phase Progression and Triggers an ATM-Dependent DNA Damage Response

(2011) A. Fradet-Turcotte et al.   JOURNAL OF VIROLOGY

Collisions between Replication and Transcription Complexes Cause Common Fragile Site Instability at the Longest Human Genes

(2011) Anne Helmrich et al.   MOLECULAR CELL

Cell-type-specific replication initiation programs set fragility of the FRA3B fragile site

(2011) Anne Letessier et al.   NATURE

Gene bookmarking accelerates the kinetics of post-mitotic transcriptional re-activation

(2011) Rui Zhao et al.   NATURE CELL BIOLOGY

Molecular profiling of common fragile sites in human fibroblasts

(2011) Benoî Le Tallec et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Dr.VIS: a database of human disease-related viral integration sites

(2011) X. Zhao et al.   NUCLEIC ACIDS RESEARCH

Dynamic acetylation of all lysine-4 trimethylated histone H3 is evolutionarily conserved and mediated by p300/CBP

(2011) N. T. Crump et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Common fragile sites: mechanisms of instability revisited

(2011) Michelle Debatisse et al.   TRENDS IN GENETICS

Suppression of inflammation by a synthetic histone mimic

(2010) Edwige Nicodeme et al.   NATURE

Genome-wide siRNA screen identifies SMCX, EP400, and Brd4 as E2-dependent regulators of human papillomavirus oncogene expression

(2010) Jennifer A. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

WHAT do viruses BET on?

(2009) Magdalena Weidner-Glunde   Frontiers in Bioscience-Landmark

Common fragile sites are characterized by histone hypoacetylation

(2009) Yanwen Jiang et al.   HUMAN MOLECULAR GENETICS

Papillomavirus E2 Proteins and the Host Brd4 Protein Associate with Transcriptionally Active Cellular Chromatin

(2009) M. K. Jang et al.   JOURNAL OF VIROLOGY

A review of human carcinogens—Part B: biological agents

(2009) Véronique Bouvard et al.   LANCET ONCOLOGY

Brd4 Marks Select Genes on Mitotic Chromatin and Directs Postmitotic Transcription

(2009) Anup Dey et al.   MOLECULAR BIOLOGY OF THE CELL

Replication stress induces sister-chromatid bridging at fragile site loci in mitosis

(2009) Kok Lung Chan et al.   NATURE CELL BIOLOGY

The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities

(2009) Valeria Naim et al.   NATURE CELL BIOLOGY

Human Papillomaviruses Activate the ATM DNA Damage Pathway for Viral Genome Amplification upon Differentiation

(2009) Cary A. Moody et al.   PLoS Pathogens

The Majority of Viral-Cellular Fusion Transcripts in Cervical Carcinomas Cotranscribe Cellular Sequences of Known or Predicted Genes

(2008) I. Kraus et al.   CANCER RESEARCH

The Bromodomain Protein Brd4 Stimulates G1Gene Transcription and Promotes Progression to S Phase

(2008) Kazuki Mochizuki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Dimerization of the Papillomavirus E2 Protein Is Required for Efficient Mitotic Chromosome Association and Brd4 Binding

(2008) J. Cardenas-Mora et al.   JOURNAL OF VIROLOGY

Analyzing ChIP-chip Data Using Bioconductor

(2008) Joern Toedling et al.   PLoS Computational Biology