Journal
VIRUSES-BASEL
Volume 5, Issue 6, Pages 1374-1394Publisher
MDPI
DOI: 10.3390/v5061374
Keywords
Brd4; BET protein; HPV; papillomavirus; transcription; chromatin; replication; tethering; partitioning; bromodomain
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Funding
- Intramural Research Program of the NIAID
- NIH
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The Brd4 protein is an epigenetic reader that is central to regulation of cellular transcription and mitotic bookmarking. The transcription and replication proteins of many viruses interact with Brd4. We describe the multiple roles of Brd4 in the papillomavirus lifecycle.
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