Intact Type I Interferon Production and IRF7 Function in Sooty Mangabeys

Early Resolution of Acute Immune Activation and Induction of PD-1 in SIV-Infected Sooty Mangabeys Distinguishes Nonpathogenic from Pathogenic Infection in Rhesus Macaques

(2014) J. D. Estes et al.   JOURNAL OF IMMUNOLOGY

OASL1 inhibits translation of the type I interferon–regulating transcription factor IRF7

(2013) Myeong Sup Lee et al.   NATURE IMMUNOLOGY

Multifunctional Double-negative T Cells in Sooty Mangabeys Mediate T-helper Functions Irrespective of SIV Infection

(2013) Vasudha Sundaravaradan et al.   PLoS Pathogens

Treatment of SIV-infected sooty mangabeys with a type-I IFN agonist results in decreased virus replication without inducing hyperimmune activation

(2012) T. H. Vanderford et al.   BLOOD

Differential infection patterns of CD4+ T cells and lymphoid tissue viral burden distinguish progressive and nonprogressive lentiviral infections

(2012) J. M. Brenchley et al.   BLOOD

Innate Immune Recognition of HIV-1

(2012) Akiko Iwasaki   IMMUNITY

Recent advances in understanding viral evasion of type I interferon

(2012) Kathryne E. Taylor et al.   IMMUNOLOGY

Association of PHRF1-IRF7 region polymorphism with clinical manifestations of systemic lupus erythematosus in a Japanese population

(2012) A Kawasaki et al.   LUPUS

A FOXO3–IRF7 gene regulatory circuit limits inflammatory sequelae of antiviral responses

(2012) Vladimir Litvak et al.   NATURE

Role of retroviral restriction factors in the interferon- -mediated suppression of HIV-1 in vivo

(2012) S. K. Pillai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Natural SIV Hosts: Showing AIDS the Door

(2012) Ann Chahroudi et al.   SCIENCE

Polymorphisms in interferon regulatory factor 7 reduce interferon-α responses of plasmacytoid dendritic cells to HIV-1

(2011) Judy Chang et al.   AIDS

Spatiotemporal trafficking of HIV in human plasmacytoid dendritic cells defines a persistently IFN-α–producing and partially matured phenotype

(2011) Meagan O’Brien et al.   JOURNAL OF CLINICAL INVESTIGATION

Lack of clinical AIDS in SIV-infected sooty mangabeys with significant CD4+ T cell loss is associated with double-negative T cells

(2011) Jeffrey M. Milush et al.   JOURNAL OF CLINICAL INVESTIGATION

Comparative transcriptomics of extreme phenotypes of human HIV-1 infection and SIV infection in sooty mangabey and rhesus macaque

(2011) Margalida Rotger et al.   JOURNAL OF CLINICAL INVESTIGATION

Distinctive TLR7 Signaling, Type I IFN Production, and Attenuated Innate and Adaptive Immune Responses to Yellow Fever Virus in a Primate Reservoir Host

(2011) J. N. Mandl et al.   JOURNAL OF IMMUNOLOGY

CD4+ T-Cell Deficiency in HIV Patients Responding to Antiretroviral Therapy Is Associated With Increased Expression of Interferon-Stimulated Genes in CD4+ T Cells

(2011) Sonia Fernandez et al.   JOURNAL OF INFECTIOUS DISEASES

Low levels of SIV infection in sooty mangabey central memory CD4+ T cells are associated with limited CCR5 expression

(2011) Mirko Paiardini et al.   NATURE MEDICINE

Interferon-stimulated genes and their antiviral effector functions

(2011) John W Schoggins et al.   Current Opinion in Virology

Association of a functional IRF7 variant with systemic lupus erythematosus

(2010) Qiong Fu et al.   ARTHRITIS AND RHEUMATISM

Nonprogressive and Progressive Primate Immunodeficiency Lentivirus Infections

(2010) Jason M. Brenchley et al.   IMMUNITY

A Five-Year Longitudinal Analysis of Sooty Mangabeys Naturally Infected with Simian Immunodeficiency Virus Reveals a Slow but Progressive Decline in CD4+ T-Cell Count Whose Magnitude Is Not Predicted by Viral Load or Immune Activation

(2010) J. Taaffe et al.   JOURNAL OF VIROLOGY

Downregulation of Robust Acute Type I Interferon Responses Distinguishes Nonpathogenic Simian Immunodeficiency Virus (SIV) Infection of Natural Hosts from Pathogenic SIV Infection of Rhesus Macaques

(2010) L. D. Harris et al.   JOURNAL OF VIROLOGY

A map of human genome variation from population-scale sequencing

(2010) Richard M. Durbin et al.   NATURE

Nonpathogenesis of Simian Immunodeficiency Virus Infection Is Associated with Reduced Inflammation and Recruitment of Plasmacytoid Dendritic Cells to Lymph Nodes, Not to Lack of an Interferon Type I Response, during the Acute Phase

(2009) L. Campillo-Gimenez et al.   JOURNAL OF VIROLOGY

CD4 downregulation by memory CD4+ T cells in vivo renders African green monkeys resistant to progressive SIVagm infection

(2009) Coreen M Beaumier et al.   NATURE MEDICINE

Transcriptional Profiling in Pathogenic and Non-Pathogenic SIV Infections Reveals Significant Distinctions in Kinetics and Tissue Compartmentalization

(2009) Sharon Lederer et al.   PLoS Pathogens

Differential Th17 CD4 T-cell depletion in pathogenic and nonpathogenic lentiviral infections

(2008) J. M. Brenchley et al.   BLOOD

Differential CD4+ T-Lymphocyte Apoptosis and Bystander T-Cell Activation in Rhesus Macaques and Sooty Mangabeys during Acute Simian Immunodeficiency Virus Infection

(2008) M. Meythaler et al.   JOURNAL OF VIROLOGY

Divergent TLR7 and TLR9 signaling and type I interferon production distinguish pathogenic and nonpathogenic AIDS virus infections

(2008) Judith N Mandl et al.   NATURE MEDICINE

Inefficient Nef-Mediated Downmodulation of CD3 and MHC-I Correlates with Loss of CD4+ T Cells in Natural SIV Infection

(2008) Michael Schindler et al.   PLoS Pathogens