Using Existing Drugs as Leads for Broad Spectrum Anthelmintics Targeting Protein Kinases

Transcription profiling reveals stage- and function-dependent expression patterns in the filarial nematode Brugia malayi

(2012) Ben-Wen Li et al.   BMC GENOMICS

Selective effect of the anthelmintic bephenium on Haemonchus contortus levamisole-sensitive acetylcholine receptors

(2012) Claude L. Charvet et al.   INVERTEBRATE NEUROSCIENCE

Human p38 mitogen-activated protein kinase inhibitor drugs inhibit Plasmodium falciparum replication

(2011) Michael J. Brumlik et al.   EXPERIMENTAL PARASITOLOGY

Target repurposing for neglected diseases

(2011) Michael P Pollastri et al.   Future Medicinal Chemistry

Comprehensive analysis of kinase inhibitor selectivity

(2011) Mindy I Davis et al.   NATURE BIOTECHNOLOGY

The draft genome of the parasitic nematode Trichinella spiralis

(2011) Makedonka Mitreva et al.   NATURE GENETICS

Nematode.net update 2011: addition of data sets and tools featuring next-generation sequencing data

(2011) J. Martin et al.   NUCLEIC ACIDS RESEARCH

WormBase 2012: more genomes, more data, new website

(2011) K. Yook et al.   NUCLEIC ACIDS RESEARCH

Targeting Protein-Protein Interactions for Parasite Control

(2011) Christina M. Taylor et al.   PLoS One

Crystal Structures of Two Aminoglycoside Kinases Bound with a Eukaryotic Protein Kinase Inhibitor

(2011) Desiree H. Fong et al.   PLoS One

HelmCoP: An Online Resource for Helminth Functional Genomics and Drug and Vaccine Targets Prioritization

(2011) Sahar Abubucker et al.   PLoS One

Open Babel: An open chemical toolbox

(2011) Noel M O'Boyle et al.   Journal of Cheminformatics

Gender-Associated Genes in Filarial Nematodes Are Important for Reproduction and Potential Intervention Targets

(2011) Ben-Wen Li et al.   PLoS Neglected Tropical Diseases

Cytoscape 2.8: new features for data integration and network visualization

(2010) M. E. Smoot et al.   BIOINFORMATICS

ExprEssence - Revealing the essence of differential experimental data in the context of an interaction/regulation net-work

(2010) Gregor Warsow et al.   BMC Systems Biology

Rho-kinase inhibition: a novel therapeutic target for the treatment of cardiovascular diseases

(2010) Ming Dong et al.   DRUG DISCOVERY TODAY

Casein kinase 1: Complexity in the family

(2010) Jit Kong Cheong et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

cAMP-dependent protein kinase from Plasmodium falciparum: an update

(2010) NATHALIE WURTZ et al.   PARASITOLOGY

The Current Status of Drug Discovery Against the Human Kinome

(2009) Richard M. Eglen et al.   ASSAY AND DRUG DEVELOPMENT TECHNOLOGIES

Pharmacotherapy of helminth infection

(2009) Erwin van den Enden   EXPERT OPINION ON PHARMACOTHERAPY

Massively parallel sequencing of the polyadenylated transcriptome of C. elegans

(2009) L. W. Hillier et al.   GENOME RESEARCH

Casein kinase 1 isoform 2 is essential for bloodstream form Trypanosoma brucei

(2009) Michael D. Urbaniak   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

Helminth Genomics: The Implications for Human Health

(2009) Paul J. Brindley et al.   PLoS Neglected Tropical Diseases

Characterization and inhibition of a p38-like mitogen-activated protein kinase (MAPK) from Echinococcus multilocularis: Antiparasitic activities of p38 MAPK inhibitors

(2008) Verena Gelmedin et al.   BIOCHEMICAL PHARMACOLOGY

Biotransformation of [14C]Dasatinib: In Vitro Studies in Rat, Monkey, and Human and Disposition after Administration to Rats and Monkeys

(2008) L. J. Christopher et al.   DRUG METABOLISM AND DISPOSITION

Rho Kinase Inhibition in Severe Malaria: Thwarting Parasite‐Induced Collateral Damage to Endothelia

(2008) Zacharie Taoufiq et al.   JOURNAL OF INFECTIOUS DISEASES

Fresh hope to can the worms

(2008) Roger K. Prichard et al.   NATURE

Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

(2008) Pierre Abad et al.   NATURE BIOTECHNOLOGY

InterPro: the integrative protein signature database

(2008) S. Hunter et al.   NUCLEIC ACIDS RESEARCH

siRNA-mediated knockdown of a splice variant of the PK-A catalytic subunit gene causes adult-onset paralysis in C. elegans

(2007) Patricia Murray et al.   GENE