Replication Vesicles are Load- and Choke-Points in the Hepatitis C Virus Lifecycle

Persistence of HCV in Quiescent Hepatic Cells Under Conditions of an Interferon-Induced Antiviral Response

(2012) Oliver Bauhofer et al.   GASTROENTEROLOGY

Identification of type I and type II interferon-induced effectors controlling hepatitis C virus replication

(2012) Philippe Metz et al.   HEPATOLOGY

Antiviral strategies in hepatitis C virus infection

(2012) Christoph Sarrazin et al.   JOURNAL OF HEPATOLOGY

A compartmentalization model of hepatitis C virus replication: An appropriate distribution of HCV RNA for the effective replication

(2012) Jun Nakabayashi   JOURNAL OF THEORETICAL BIOLOGY

The specific infectivity of hepatitis C virus changes through its life cycle

(2012) Sun Ju Keum et al.   VIROLOGY

Three-Dimensional Architecture and Biogenesis of Membrane Structures Associated with Hepatitis C Virus Replication

(2012) Inés Romero-Brey et al.   PLoS Pathogens

False negative rates in Drosophila cell-based RNAi screens: a case study

(2011) Matthew Booker et al.   BMC GENOMICS

Mouse Hepatic Cells Support Assembly of Infectious Hepatitis C Virus Particles

(2011) Gang Long et al.   GASTROENTEROLOGY

An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver Diseases

(2011) Marc G. Ghany et al.   HEPATOLOGY

Small Molecules Targeting Hepatitis C Virus-Encoded NS5A Cause Subcellular Redistribution of Their Target: Insights into Compound Modes of Action

(2011) P. Targett-Adams et al.   JOURNAL OF VIROLOGY

A diverse range of gene products are effectors of the type I interferon antiviral response

(2011) John W. Schoggins et al.   NATURE

Understanding the nature of early HCV RNA blips and the use of mathematical modeling of viral kinetics during IFN-based therapy

(2011) J. Guedj et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatitis c virus and host cell lipids: An intimate connection

(2011) Gualtiero Alvisi et al.   RNA Biology

RNA recombination in pestiviruses: Cellular RNA sequences in viral genomes highlight the role of host factors for viral persistence and lethal disease

(2011) Paul Becher et al.   RNA Biology

Resistance to anti-HCV protease inhibitors

(2011) Alexander J Thompson et al.   Current Opinion in Virology

Mathematical Model of Viral Kinetics In Vitro Estimates the Number of E2-CD81 Complexes Necessary for Hepatitis C Virus Entry

(2011) Pranesh Padmanabhan et al.   PLoS Computational Biology

SensSB: a software toolbox for the development and sensitivity analysis of systems biology models

(2010) Maria Rodriguez-Fernandez et al.   BIOINFORMATICS

A Comprehensive Hepatitis C Viral Kinetic Model Explaining Cure

(2010) E Snoeck et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Trade-offs in resource allocation in the intracellular life-cycle of hepatitis C virus

(2010) Alison K. McLean et al.   JOURNAL OF THEORETICAL BIOLOGY

Rapid Emergence of Protease Inhibitor Resistance in Hepatitis C Virus

(2010) L. Rong et al.   Science Translational Medicine

Composition and Three-Dimensional Architecture of the Dengue Virus Replication and Assembly Sites

(2009) Sonja Welsch et al.   Cell Host & Microbe

A Functional Genomic Screen Identifies Cellular Cofactors of Hepatitis C Virus Replication

(2009) Andrew W. Tai et al.   Cell Host & Microbe

Class III Phosphatidylinositol 4-Kinase Alpha and Beta Are Novel Host Factor Regulators of Hepatitis C Virus Replication

(2009) J. Borawski et al.   JOURNAL OF VIROLOGY

The Hepatitis C Virus Core Protein Contains a BH3 Domain That Regulates Apoptosis through Specific Interaction with Human Mcl-1

(2009) N. K. Mohd-Ismail et al.   JOURNAL OF VIROLOGY

Modeling Subgenomic Hepatitis C Virus RNA Kinetics during Treatment with Alpha Interferon

(2009) H. Dahari et al.   JOURNAL OF VIROLOGY

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

A genome-wide genetic screen for host factors required for hepatitis C virus propagation

(2009) Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Essential Role of Cyclophilin A for Hepatitis C Virus Replication and Virus Production and Possible Link to Polyprotein Cleavage Kinetics

(2009) Artur Kaul et al.   PLoS Pathogens

Sloppiness, robustness, and evolvability in systems biology

(2008) Bryan C Daniels et al.   CURRENT OPINION IN BIOTECHNOLOGY

A methodology for performing global uncertainty and sensitivity analysis in systems biology

(2008) Simeone Marino et al.   JOURNAL OF THEORETICAL BIOLOGY

Hepatitis C virus infection protein network

(2008) B de Chassey et al.   Molecular Systems Biology

VirHostNet: a knowledge base for the management and the analysis of proteome-wide virus–host interaction networks

(2008) Vincent Navratil et al.   NUCLEIC ACIDS RESEARCH

Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists

(2008) Da Wei Huang et al.   NUCLEIC ACIDS RESEARCH

Interferons and viruses: an interplay between induction, signalling, antiviral responses and virus countermeasures

(2007) R. E. Randall et al.   JOURNAL OF GENERAL VIROLOGY