Taking the plunge: integrating structural, enzymatic and computational insights into a unified model for membrane-immersed rhomboid proteolysis

Emerging roles for lipids in shaping membrane-protein function

(2009) Rob Phillips et al.   NATURE

Rhomboid Protease Dynamics and Lipid Interactions

(2009) Ana-Nicoleta Bondar et al.   STRUCTURE

Rhomboid Proteases and their Biological Functions

(2008) Matthew Freeman   Annual Review of Genetics

In vivo analysis reveals substrate-gating mutants of a rhomboid intramembrane protease display increased activity in living cells

(2008) Sinisa Urban et al.   BIOLOGICAL CHEMISTRY

Application of activity-based probes to the study of enzymes involved in cancer progression

(2008) Margot G Paulick et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

Core principles of intramembrane proteolysis: comparison of rhomboid and site-2 family proteases

(2008) S URBAN et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

An Entamoeba histolytica rhomboid protease with atypical specificity cleaves a surface lectin involved in phagocytosis and immune evasion

(2008) L. A. Baxt et al.   GENES & DEVELOPMENT

Proteases: Multifunctional Enzymes in Life and Disease

(2008) Carlos López-Otín et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Unconventional serine proteases: Variations on the catalytic Ser/His/Asp triad configuration

(2008) Özlem Doğan Ekici et al.   PROTEIN SCIENCE