A Multi-Step Process of Viral Adaptation to a Mutagenic Nucleoside Analogue by Modulation of Transition Types Leads to Extinction-Escape

Unfinished Stories on Viral Quasispecies and Darwinian Views of Evolution

(2010) Antonio Más et al.   JOURNAL OF MOLECULAR BIOLOGY

Structure of Foot-and-Mouth Disease Virus Mutant Polymerases with Reduced Sensitivity to Ribavirin

(2010) C. Ferrer-Orta et al.   JOURNAL OF VIROLOGY

Competition-colonization dynamics in an RNA virus

(2010) S. Ojosnegros et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural insights into replication initiation and elongation processes by the FMDV RNA-dependent RNA polymerase

(2009) Cristina Ferrer-Orta et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Effect of Ribavirin on the Mutation Rate and Spectrum of Hepatitis C Virus In Vivo

(2009) J. M. Cuevas et al.   JOURNAL OF VIROLOGY

Biological Effect of Muller's Ratchet: Distant Capsid Site Can Affect Picornavirus Protein Processing

(2009) C. Escarmis et al.   JOURNAL OF VIROLOGY

Counteracting Quasispecies Adaptability: Extinction of a Ribavirin-Resistant Virus Mutant by an Alternative Mutagenic Treatment

(2009) Celia Perales et al.   PLoS One

Potential Benefits of Sequential Inhibitor-Mutagen Treatments of RNA Virus Infections

(2009) Celia Perales et al.   PLoS Pathogens

Lethal Mutagenesis of Picornaviruses with N-6-Modified Purine Nucleoside Analogues

(2008) J. D. Graci et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Topology of evolving, mutagenized viral populations: quasispecies expansion, compression, and operation of negative selection

(2008) Samuel Ojosnegros et al.   BMC EVOLUTIONARY BIOLOGY

Molecular Characterization of a Dual Inhibitory and Mutagenic Activity of 5-Fluorouridine Triphosphate on Viral RNA Synthesis. Implications for Lethal Mutagenesis

(2008) Rubén Agudo et al.   JOURNAL OF MOLECULAR BIOLOGY

Hidden Virulence Determinants in a Viral Quasispecies In Vivo

(2008) M. Sanz-Ramos et al.   JOURNAL OF VIROLOGY

Determinants of RNA-Dependent RNA Polymerase (In)fidelity Revealed by Kinetic Analysis of the Polymerase Encoded by a Foot-and-Mouth Disease Virus Mutant with Reduced Sensitivity to Ribavirin

(2008) A. Arias et al.   JOURNAL OF VIROLOGY

Virus Attenuation by Genome-Scale Changes in Codon Pair Bias

(2008) J. R. Coleman et al.   SCIENCE