Counteracting Quasispecies Adaptability: Extinction of a Ribavirin-Resistant Virus Mutant by an Alternative Mutagenic Treatment

Future prospects for the treatment of rapidly evolving viral pathogens: insights from evolutionary biology

(2008) Esteban Domingo et al.   EXPERT OPINION ON BIOLOGICAL THERAPY

Naturally occurring dominant resistance mutations to hepatitis C virus protease and polymerase inhibitors in treatment-naïve patients

(2008) Thomas Kuntzen et al.   HEPATOLOGY

Dynamics of picornavirus RNA replication within infected cells

(2008) G. J. Belsham et al.   JOURNAL OF GENERAL VIROLOGY

Molecular Characterization of a Dual Inhibitory and Mutagenic Activity of 5-Fluorouridine Triphosphate on Viral RNA Synthesis. Implications for Lethal Mutagenesis

(2008) Rubén Agudo et al.   JOURNAL OF MOLECULAR BIOLOGY

Hidden Virulence Determinants in a Viral Quasispecies In Vivo

(2008) M. Sanz-Ramos et al.   JOURNAL OF VIROLOGY

Determinants of RNA-Dependent RNA Polymerase (In)fidelity Revealed by Kinetic Analysis of the Polymerase Encoded by a Foot-and-Mouth Disease Virus Mutant with Reduced Sensitivity to Ribavirin

(2008) A. Arias et al.   JOURNAL OF VIROLOGY

Engineering attenuated virus vaccines by controlling replication fidelity

(2008) Marco Vignuzzi et al.   NATURE MEDICINE

Minority HIV-1 Drug Resistance Mutations Are Present in Antiretroviral Treatment–Naïve Populations and Associate with Reduced Treatment Efficacy

(2008) Jeffrey A Johnson et al.   PLOS MEDICINE

Repeated Bottleneck Transfers Can Lead to Non-cytocidal Forms of a Cytopathic Virus: Implications for Viral Extinction

(2007) Cristina Escarmís et al.   JOURNAL OF MOLECULAR BIOLOGY

Naturally occurring NS3-protease-inhibitor resistant mutant A156T in the liver of an untreated chronic hepatitis C patient

(2007) Maria Cubero et al.   VIROLOGY