Therapeutic control of leishmaniasis by inhibitors of the mammalian target of rapamycin

Arginase activity in pathogenic and non-pathogenic species of Leishmania parasites

(2017) Alireza Badirzadeh et al.   PLoS Neglected Tropical Diseases

Human Neutrophil Peptide 1 as immunotherapeutic agent against Leishmania infected BALB/c mice

(2017) Zahra Abdossamadi et al.   PLoS Neglected Tropical Diseases

Solid lipid nanoparticle loaded with paromomycin: in vivo efficacy against Leishmania tropica infection in BALB/c mice model

(2016) Maryam Heidari-Kharaji et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Enhanced paromomycin efficacy by solid lipid nanoparticle formulation againstLeishmaniain mice model

(2016) M. Heidari-Kharaji et al.   PARASITE IMMUNOLOGY

Leishmaniasis in immunosuppressed individuals

(2014) J. van Griensven et al.   CLINICAL MICROBIOLOGY AND INFECTION

Genetic Analysis of Leishmania donovani Tropism Using a Naturally Attenuated Cutaneous Strain

(2014) Wen Wei Zhang et al.   PLoS Pathogens

Amphotericin B Formulations: A Comparative Review of Efficacy and Toxicity

(2013) Richard J. Hamill   DRUGS

Association of Pro-Inflammatory Cytokines and Iron Regulatory Protein 2 (IRP2) with Leishmania Burden in Canine Visceral Leishmaniasis

(2013) Paulo Ricardo Porfírio do Nascimento et al.   PLoS One

Management of trypanosomiasis and leishmaniasis

(2012) M. P. Barrett et al.   BRITISH MEDICAL BULLETIN

Monoterpenic aldehydes as potential anti-Leishmania agents: Activity of Cymbopogon citratus and citral on L. infantum, L. tropica and L. major

(2012) M. Machado et al.   EXPERIMENTAL PARASITOLOGY

Isoenzyme and ultrastructural characterization of Leishmania tropica axenic amastigotes and promastigotes

(2012) Gholam Reza Hatam et al.   PARASITOLOGY RESEARCH

Leishmaniasis Worldwide and Global Estimates of Its Incidence

(2012) Jorge Alvar et al.   PLoS One

Rapamycin-Induced Insulin Resistance Is Mediated by mTORC2 Loss and Uncoupled from Longevity

(2012) D. W. Lamming et al.   SCIENCE

Differential Regulation of Simultaneous Antitumor and Alloreactive CD8+ T-Cell Responses in the Same Host by Rapamycin

(2011) S. Maleki Vareki et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Sirolimus Enhances the Magnitude and Quality of Viral-Specific CD8+ T-Cell Responses to Vaccinia Virus Vaccination in Rhesus Macaques

(2011) A. P. Turner et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Autophagy in protists

(2011) Michael Duszenko et al.   Autophagy

Targeting mTOR with rapamycin: One dose does not fit all

(2011) David A. Foster et al.   CELL CYCLE

Recent advances in leishmaniasis treatment

(2011) Tatiana S. Tiuman et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

mTOR signaling pathway regulates the IL-12/IL-10 axis in Leishmania donovani infection

(2011) Satyanarayana Swamy Cheekatla et al.   MEDICAL MICROBIOLOGY AND IMMUNOLOGY

Qualitative and quantitative polymerase chain reaction (PCR) for detection of Leishmania in spleen samples from naturally infected dogs

(2011) Manuela da Silva Solcà et al.   VETERINARY PARASITOLOGY

The Susceptibility of Trypanosomatid Pathogens to PI3/mTOR Kinase Inhibitors Affords a New Opportunity for Drug Repurposing

(2011) Rosario Diaz-Gonzalez et al.   PLoS Neglected Tropical Diseases

Cutting Edge: Rapamycin Augments Pathogen-Specific but Not Graft-Reactive CD8+ T Cell Responses

(2010) I. R. Ferrer et al.   JOURNAL OF IMMUNOLOGY

Insulin-like growth factor-I induced and constitutive arginase activity differs among isolates of Leishmania derived from patients with diverse clinical forms of Leishmania braziliensis infection

(2010) Célia M.V. Vendrame et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

Discovery of GSK2126458, a Highly Potent Inhibitor of PI3K and the Mammalian Target of Rapamycin

(2010) Steven D. Knight et al.   ACS Medicinal Chemistry Letters

Ku-0063794 is a specific inhibitor of the mammalian target of rapamycin (mTOR)

(2009) Juan M. García-Martínez et al.   BIOCHEMICAL JOURNAL

mTOR regulates memory CD8 T-cell differentiation

(2009) Koichi Araki et al.   NATURE