Multiple Immune Factors Are Involved in Controlling Acute and Chronic Chikungunya Virus Infection

Chikungunya outbreak in the Caribbean region, December 2013 to March 2014, and the significance for Europe

(2014) W Van Bortel et al.   Eurosurveillance

NKG2D-RAE-1 Receptor-Ligand Variation Does Not Account for the NK Cell Defect in Nonobese Diabetic Mice

(2014) L. M. Maier et al.   JOURNAL OF IMMUNOLOGY

Reduced Regulatory T Cell Diversity in NOD Mice Is Linked to Early Events in the Thymus

(2014) C. Ferreira et al.   JOURNAL OF IMMUNOLOGY

Attenuating Mutations in nsP1 Reveal Tissue-Specific Mechanisms for Control of Ross River Virus Infection

(2014) K. A. Stoermer Burrack et al.   JOURNAL OF VIROLOGY

CCR2 Deficiency Promotes Exacerbated Chronic Erosive Neutrophil-Dominated Chikungunya Virus Arthritis

(2014) Y. S. Poo et al.   JOURNAL OF VIROLOGY

Crippling Virus Set to Conquer Western Hemisphere

(2014) M. Enserink   SCIENCE

Chikungunya fever: Epidemiology, clinical syndrome, pathogenesis and therapy

(2013) Simon-Djamel Thiberville et al.   ANTIVIRAL RESEARCH

Neutralizing monoclonal antibodies to the E2 protein of chikungunya virus protects against disease in a mouse model

(2013) Lucas Y.H. Goh et al.   CLINICAL IMMUNOLOGY

An Essential Role of Antibodies in the Control of Chikungunya Virus Infection

(2013) F.-M. Lum et al.   JOURNAL OF IMMUNOLOGY

Chronic Joint Disease Caused by Persistent Chikungunya Virus Infection Is Controlled by the Adaptive Immune Response

(2013) D. W. Hawman et al.   JOURNAL OF VIROLOGY

Inflammasome Adaptor Protein Apoptosis-Associated Speck-Like Protein Containing CARD (ASC) Is Critical for the Immune Response and Survival in West Nile Virus Encephalitis

(2013) M. Kumar et al.   JOURNAL OF VIROLOGY

RNA-mediated interference and reverse transcription control the persistence of RNA viruses in the insect model Drosophila

(2013) Bertsy Goic et al.   NATURE IMMUNOLOGY

Hydrazinocurcumin Encapsuled Nanoparticles “Re-Educate” Tumor-Associated Macrophages and Exhibit Anti-Tumor Effects on Breast Cancer Following STAT3 Suppression

(2013) Xiwen Zhang et al.   PLoS One

Identical Strength of the T Cell Responses against E2, nsP1 and Capsid CHIKV Proteins in Recovered and Chronic Patients after the Epidemics of 2005-2006 in La Reunion Island

(2013) Jean-Jacques Hoarau et al.   PLoS One

Deciphering the protective role of adaptive immunity to CHIKV/IRES a novel candidate vaccine against Chikungunya in the A129 mouse model

(2013) Haiyan Chu et al.   VACCINE

A Neutralizing Monoclonal Antibody Targeting the Acid-Sensitive Region in Chikungunya Virus E2 Protects from Disease

(2013) Suganya Selvarajah et al.   PLoS Neglected Tropical Diseases

Chikungunya Virus Infection Results in Higher and Persistent Viral Replication in Aged Rhesus Macaques Due to Defects in Anti-Viral Immunity

(2013) Ilhem Messaoudi et al.   PLoS Neglected Tropical Diseases

Effective Chikungunya Virus-like Particle Vaccine Produced in Insect Cells

(2013) Stefan W. Metz et al.   PLoS Neglected Tropical Diseases

Development of a Highly Protective Combination Monoclonal Antibody Therapy against Chikungunya Virus

(2013) Pankaj Pal et al.   PLoS Pathogens

Gene profiling of Chikungunya virus arthritis in a mouse model reveals significant overlap with rheumatoid arthritis

(2012) Helder I. Nakaya et al.   ARTHRITIS AND RHEUMATISM

A defect in cell death of macrophages is a conserved feature of nonobese diabetic mouse

(2012) Hun Sik Kim et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Glucagon-like peptide-1 (GLP-1) induces M2 polarization of human macrophages via STAT3 activation

(2012) Daisuke Shiraishi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Macrophages from Nonobese Diabetic Mouse Have a Selective Defect in IFN-γ but Not IFN-α/β Receptor Pathway

(2012) Myung-Shik Lee et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Genetic Ablation of Arginase 1 in Macrophages and Neutrophils Enhances Clearance of an Arthritogenic Alphavirus

(2012) K. A. Stoermer et al.   JOURNAL OF IMMUNOLOGY

A Pathogenic Role for CD4+ T Cells during Chikungunya Virus Infection in Mice

(2012) T.-H. Teo et al.   JOURNAL OF IMMUNOLOGY

Use of Human Monoclonal Antibodies to Treat Chikungunya Virus Infection

(2012) Jan Fric et al.   JOURNAL OF INFECTIOUS DISEASES

Interferon Response Factors 3 and 7 Protect against Chikungunya Virus Hemorrhagic Fever and Shock

(2012) Penny A. Rudd et al.   JOURNAL OF VIROLOGY

A novel pathway of presentation by class II-MHC molecules involving peptides or denatured proteins important in autoimmunity

(2012) James F. Mohan et al.   MOLECULAR IMMUNOLOGY

Arthritogenic alphaviruses—an overview

(2012) Andreas Suhrbier et al.   Nature Reviews Rheumatology

Effect of Serum Heat-Inactivation and Dilution on Detection of Anti-WNV Antibodies in Mice by West Nile Virus E-protein Microsphere Immunoassay

(2012) Madhuri Namekar et al.   PLoS One

Viremic profiles in asymptomatic and symptomatic chikungunya fever: a blood transfusion threat?

(2012) Hatsadee Appassakij et al.   TRANSFUSION

Deciphering the differential response of two human fibroblast cell lines following Chikungunya virus infection

(2012) Vincent G Thon-Hon et al.   Virology Journal

HIV–1 Dynamics: A Reappraisal of Host and Viral Factors, as well as Methodological Issues

(2012) Heather A. Prentice et al.   Viruses-Basel

Mannose Binding Lectin Is Required for Alphavirus-Induced Arthritis/Myositis

(2012) Bronwyn M. Gunn et al.   PLoS Pathogens

Vector-Borne Transmission Imposes a Severe Bottleneck on an RNA Virus Population

(2012) Naomi L. Forrester et al.   PLoS Pathogens

A Mouse Model of Chikungunya Virus–Induced Musculoskeletal Inflammatory Disease

(2011) Thomas E. Morrison et al.   AMERICAN JOURNAL OF PATHOLOGY

Natural killer cells and T cells induce different types ofskin reactions during recall responses to haptens

(2011) Paul Rouzaire et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

License to kill: Formulation requirements for optimal priming of CD8+ CTL responses with particulate vaccine delivery systems

(2011) Camilla Foged et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Sidestepping maternal antibody: a lesson from measles virus vaccination

(2011) Dhohyung Kim et al.   Expert Review of Clinical Immunology

Alphavirus-Induced Encephalomyelitis: Antibody-Secreting Cells and Viral Clearance from the Nervous System

(2011) T. U. Metcalf et al.   JOURNAL OF VIROLOGY

Identification and Characterization of a Ross River Virus Variant That Grows Persistently in Macrophages, Shows Altered Disease Kinetics in a Mouse Model, and Exhibits Resistance to Type I Interferon

(2011) B. A. Lidbury et al.   JOURNAL OF VIROLOGY

A cluster of coregulated genes determines TGF- -induced regulatory T-cell (Treg) dysfunction in NOD mice

(2011) A. M. D'Alise et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arbovirus high fidelity variant loses fitness in mosquitoes and mice

(2011) L. L. Coffey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A complex adenovirus vaccine against chikungunya virus provides complete protection against viraemia and arthritis

(2011) Danher Wang et al.   VACCINE

Role of Proinflammatory Cytokines and Chemokines in Chronic Arthropathy in CHIKV Infection

(2011) Itta Krishna Chaaithanya et al.   VIRAL IMMUNOLOGY

Characterization of Chikungunya virus infection in human neuroblastoma SH-SY5Y cells: Role of apoptosis in neuronal cell death

(2011) R. Dhanwani et al.   VIRUS RESEARCH

IRGM Is a Common Target of RNA Viruses that Subvert the Autophagy Network

(2011) Isabel Pombo Grégoire et al.   PLoS Pathogens

Chikungunya Virus Neutralization Antigens and Direct Cell-to-Cell Transmission Are Revealed by Human Antibody-Escape Mutants

(2011) Chia Yin Lee et al.   PLoS Pathogens

Disease exacerbation by etanercept in a mouse model of alphaviral arthritis and myositis

(2010) Ali Zaid et al.   ARTHRITIS AND RHEUMATISM

Sindbis Virus Usurps the Cellular HuR Protein to Stabilize Its Transcripts and Promote Productive Infections in Mammalian and Mosquito Cells

(2010) Kevin J. Sokoloski et al.   Cell Host & Microbe

Emergence and clinical insights into the pathology of Chikungunya virus infection

(2010) Marie Christine Jaffar-Bandjee et al.   Expert Review of Anti-Infective Therapy

Chikungunya virus mobilizes the apoptotic machinery to invade host cell defenses

(2010) Pascale Krejbich-Trotot et al.   FASEB JOURNAL

Recovery from viral encephalomyelitis: immune-mediated noncytolytic virus clearance from neurons

(2010) Diane E. Griffin   IMMUNOLOGIC RESEARCH

Chikungunya disease in nonhuman primates involves long-term viral persistence in macrophages

(2010) Karine Labadie et al.   JOURNAL OF CLINICAL INVESTIGATION

Type I IFN controls chikungunya virus via its action on nonhematopoietic cells

(2010) Clémentine Schilte et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Type I IFN enhances follicular B cell contribution to the T cell–independent antibody response

(2010) Cristina L. Swanson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Persistent Chronic Inflammation and Infection by Chikungunya Arthritogenic Alphavirus in Spite of a Robust Host Immune Response

(2010) J. J. Hoarau et al.   JOURNAL OF IMMUNOLOGY

Chikungunya Virus Arthritis in Adult Wild-Type Mice

(2010) J. Gardner et al.   JOURNAL OF VIROLOGY

Chikungunya Virus Nonstructural Protein 2 Inhibits Type I/II Interferon-Stimulated JAK-STAT Signaling

(2010) Jelke J. Fros et al.   JOURNAL OF VIROLOGY

Intrinsic antibody-dependent enhancement of microbial infection in macrophages: disease regulation by immune complexes

(2010) Scott B Halstead et al.   LANCET INFECTIOUS DISEASES

A virus-like particle vaccine for epidemic Chikungunya virus protects nonhuman primates against infection

(2010) Wataru Akahata et al.   NATURE MEDICINE

Biology and pathogenesis of chikungunya virus

(2010) Olivier Schwartz et al.   NATURE REVIEWS MICROBIOLOGY

Nanopatch-Targeted Skin Vaccination against West Nile Virus and Chikungunya Virus in Mice

(2010) Tarl W. Prow et al.   Small

Neurological complications of Chikungunya virus infection

(2009) HatimF Daginawala et al.   NEUROLOGY INDIA

The immunobiology of viral arthritides

(2009) Andreas Suhrbier et al.   PHARMACOLOGY & THERAPEUTICS

Accurate Strand-Specific Quantification of Viral RNA

(2009) Nicole E. Plaskon et al.   PLoS One

Chikungunya fever: CNS infection and pathologies of a re-emerging arbovirus

(2009) Trina Das et al.   PROGRESS IN NEUROBIOLOGY

Atypical manifestations of chikungunya infection

(2009) Senaka Rajapakse et al.   TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE

CD4+ T cells provide protection against acute lethal encephalitis caused by Venezuelan equine encephalitis virus

(2009) Nadezhda E. Yun et al.   VACCINE

Negative regulation of cytoplasmic RNA-mediated antiviral signaling

(2008) Akihiko Komuro et al.   CYTOKINE

Host responses to alphavirus infection

(2008) Kate D. Ryman et al.   IMMUNOLOGICAL REVIEWS

Interferons: Signaling, antiviral and viral evasion

(2008) Cláudio A. Bonjardim et al.   IMMUNOLOGY LETTERS

Complement Receptor 3 Promotes Severe Ross River Virus-Induced Disease

(2008) T. E. Morrison et al.   JOURNAL OF VIROLOGY

A Mouse Model for Chikungunya: Young Age and Inefficient Type-I Interferon Signaling Are Risk Factors for Severe Disease

(2008) Thérèse Couderc et al.   PLoS Pathogens

Chimeric alphavirus vaccine candidates for chikungunya

(2008) Eryu Wang et al.   VACCINE