Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain

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Sequence variant at 8q24.21 associates with sciatica caused by lumbar disc herniation

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Genome-Wide Association Study of Radiographic Knee Osteoarthritis in North American Caucasians

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MiR-146b is down-regulated during the chondrogenic differentiation of human bone marrow derived skeletal stem cells and up-regulated in osteoarthritis

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Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses

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Genome-wide DNA methylation profile implicates potential cartilage regeneration at the late stage of knee osteoarthritis

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Genome-Wide Association Analyses in 128,266 Individuals Identifies New Morningness and Sleep Duration Loci

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Identification of DNA methylation changes associated with disease progression in subchondral bone with site-matched cartilage in knee osteoarthritis

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Netrin-1 Contributes to Myelinated Afferent Fiber Sprouting and Neuropathic Pain

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Meta-analysis of the heritability of human traits based on fifty years of twin studies

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LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

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The transcription factors SOX9 and SOX5/SOX6 cooperate genome-wide through super-enhancers to drive chondrogenesis

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Genetics and the environment affect the relationship between depression and low back pain

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Genome-wide association and functional studies identify a role forIGFBP3in hip osteoarthritis

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A History of Lumbar Disc Herniation From Hippocrates to the 1990s

(2014) Eeric Truumees   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

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Incidence and risk factors for first-time incident low back pain: a systematic review and meta-analysis

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Report of the NIH Task Force on Research Standards for Chronic Low Back Pain

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Associations of Body Mass Index and Body Height With Low Back Pain in 829,791 Adolescents

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A meta-analysis of genome-wide association studies identifies novel variants associated with osteoarthritis of the hip

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Pleiotropy in complex traits: challenges and strategies

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Presence and extent of severe facet joint osteoarthritis are associated with back pain in older adults

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Structural Brain Changes in Chronic Pain Reflect Probably Neither Damage Nor Atrophy

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Assessment of Osteoarthritis Candidate Genes in a Meta-Analysis of Nine Genome-Wide Association Studies

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Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects

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Evaluation of the genetic overlap between osteoarthritis with body mass index and height using genome-wide association scan data

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Genetic contribution of catechol-O-methyltransferase variants in treatment outcome of low back pain: a prospective genetic association study

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Annotation of functional variation in personal genomes using RegulomeDB

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Identification of new susceptibility loci for osteoarthritis (arcOGEN): a genome-wide association study

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Corticostriatal functional connectivity predicts transition to chronic back pain

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Osteoarthritis of the spine: the facet joints

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MiR-194 Regulates Chondrogenic Differentiation of Human Adipose-Derived Stem Cells by Targeting Sox5

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Increased Expression of Netrin-1 and Its Deleted in Colorectal Cancer Receptor in Human Diseased Lumbar Intervertebral Disc Compared With Autopsy Control

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Effective Treatment of Chronic Low Back Pain in Humans Reverses Abnormal Brain Anatomy and Function

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Degenerative Magnetic Resonance Imaging Changes in Patients With Chronic Low Back Pain

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Meta-analysis of genome-wide association studies confirms a susceptibility locus for knee osteoarthritis on chromosome 7q22

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Association between Caspase-9 promoter region polymorphisms and discogenic low back pain

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Will This Patient Develop Persistent Disabling Low Back Pain?

(2010) Roger Chou   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Potential of Magnetic Resonance Imaging Findings to Refine Case Definition for Mechanical Low Back Pain in Epidemiological Studies

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Back pain, neurogenic symptoms, and physical function in relation to spondylolisthesis among elderly men

(2010) Patrick J. Denard et al.   Spine Journal

Heritability of spinal pain and consequences of spinal pain: A comprehensive genetic epidemiologic analysis using a population-based sample of 15,328 twins ages 20-71 years

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Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

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