Sequence variant at 8q24.21 associates with sciatica caused by lumbar disc herniation

Weighting sequence variants based on their annotation increases power of whole-genome association studies

(2016) Gardar Sveinbjornsson et al.   NATURE GENETICS

Meta-analysis of 375,000 individuals identifies 38 susceptibility loci for migraine

(2016) Padhraig Gormley et al.   NATURE GENETICS

Sequence variants in the PTCH1 gene associate with spine bone mineral density and osteoporotic fractures

(2016) Unnur Styrkarsdottir et al.   Nature Communications

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

(2015) Bjarni J. Vilhjálmsson et al.   AMERICAN JOURNAL OF HUMAN GENETICS

GSDMfamily genes meet autophagy

(2015) Masaru Tamura et al.   BIOCHEMICAL JOURNAL

Loss of conservedGsdma3self-regulation causes autophagy and cell death

(2015) Peiliang Shi et al.   BIOCHEMICAL JOURNAL

Incidence of Low Back Pain After Lumbar Discectomy for Herniated Disc and Its Effect on Patient-reported Outcomes

(2015) Scott L. Parker et al.   CLINICAL ORTHOPAEDICS AND RELATED RESEARCH

Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death

(2015) Jianjin Shi et al.   NATURE

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

Large-scale whole-genome sequencing of the Icelandic population

(2015) Daniel F Gudbjartsson et al.   NATURE GENETICS

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Sciatica

(2015) Allan H. Ropper et al.   NEW ENGLAND JOURNAL OF MEDICINE

Sequence variants from whole genome sequencing a large group of Icelanders

(2015) Daniel F Gudbjartsson et al.   Scientific Data

Systematic Literature Review of Imaging Features of Spinal Degeneration in Asymptomatic Populations

(2014) W. Brinjikji et al.   AMERICAN JOURNAL OF NEURORADIOLOGY

The clinical course of low back pain: a meta-analysis comparing outcomes in randomised clinical trials (RCTs) and observational studies

(2014) Majid Artus et al.   BMC MUSCULOSKELETAL DISORDERS

Meta-analysis of genome-wide association studies of adult height in East Asians identifies 17 novel loci

(2014) Meian He et al.   HUMAN MOLECULAR GENETICS

Defining the role of common variation in the genomic and biological architecture of adult human height

(2014) Andrew R Wood et al.   NATURE GENETICS

Diagnostic Criteria for Temporomandibular Disorders (DC/TMD) for Clinical and Research Applications: Recommendations of the International RDC/TMD Consortium Network* and Orofacial Pain Special Interest Group†

(2014) Eric Schiffman et al.   Journal of Oral & Facial Pain and Headache

Limited Microdiscectomy for Lumbar Disk Herniation

(2013) John Soliman et al.   JOURNAL OF SPINAL DISORDERS & TECHNIQUES

Role of cytokines in intervertebral disc degeneration: pain and disc content

(2013) Makarand V. Risbud et al.   Nature Reviews Rheumatology

An evidence-based clinical guideline for the diagnosis and treatment of lumbar disc herniation with radiculopathy

(2013) D. Scott Kreiner et al.   Spine Journal

A common variant at 8q24.21 is associated with renal cell cancer

(2013) Julius Gudmundsson et al.   Nature Communications

Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects

(2012) Frances M K Williams et al.   ANNALS OF THE RHEUMATIC DISEASES

Genetic Association Studies in Lumbar Disc Degeneration: A Systematic Review

(2012) Pasi J. Eskola et al.   PLoS One

Risk Factors for Hospitalization Due to Lumbar Disc Disease

(2012) Jens Wahlström et al.   SPINE

Peripheral neuropathy in HIV: prevalence and risk factors

(2011) Scott R Evans et al.   AIDS

A germline variant in the TP53 polyadenylation signal confers cancer susceptibility

(2011) Simon N Stacey et al.   NATURE GENETICS

Sciatica

(2010) Jean-Pierre Valat et al.   BEST PRACTICE & RESEARCH IN CLINICAL RHEUMATOLOGY

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Hundreds of variants clustered in genomic loci and biological pathways affect human height

(2010) Hana Lango Allen et al.   NATURE

The American College of Rheumatology Preliminary Diagnostic Criteria for Fibromyalgia and Measurement of Symptom Severity

(2010) Frederick Wolfe et al.   ARTHRITIS CARE & RESEARCH

Retinoic acid receptors are required for skeletal growth, matrix homeostasis and growth plate function in postnatal mouse

(2009) Julie A. Williams et al.   DEVELOPMENTAL BIOLOGY

Key susceptibility locus for nonsyndromic cleft lip with or without cleft palate on chromosome 8q24

(2009) Stefanie Birnbaum et al.   NATURE GENETICS

Prevalence and Pattern of Lumbar Magnetic Resonance Imaging Changes in a Population Study of One Thousand Forty-Three Individuals

(2009) Kenneth M. C. Cheung et al.   SPINE

Multiple Loci With Different Cancer Specificities Within the 8q24 Gene Desert

(2008) Maya Ghoussaini et al.   JNCI-Journal of the National Cancer Institute

Genes encoded within 8q24 on the amplicon of a large extrachromosomal element are selectively repressed during the terminal differentiation of HL-60 cells

(2008) Tetsuo Hirano et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Sciatica

(2008) Kika Konstantinou et al.   SPINE