8.2% of the Human Genome Is Constrained: Variation in Rates of Turnover across Functional Element Classes in the Human Lineage

The evolution of lncRNA repertoires and expression patterns in tetrapods

(2014) Anamaria Necsulea et al.   NATURE

On the Immortality of Television Sets: "Function" in the Human Genome According to the Evolution-Free Gospel of ENCODE

(2013) D. Graur et al.   Genome Biology and Evolution

Enhancer turnover and conserved regulatory function in vertebrate evolution

(2013) S. Domene et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

Is junk DNA bunk? A critique of ENCODE

(2013) W. F. Doolittle   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Comment on "Evidence of Abundant Purifying Selection in Humans for Recently Acquired Regulatory Functions"

(2013) P. Green et al.   SCIENCE

Response to Comment on "Evidence of Abundant Purifying Selection in Humans for Recently Acquired Regulatory Functions"

(2013) L. D. Ward et al.   SCIENCE

Pervasive Transcription of the Human Genome Produces Thousands of Previously Unidentified Long Intergenic Noncoding RNAs

(2013) Matthew J. Hangauer et al.   PLoS Genetics

ENCODE explained

(2012) Joseph R. Ecker et al.   NATURE

An integrated encyclopedia of DNA elements in the human genome

(2012)   NATURE

Evidence of Abundant Purifying Selection in Humans for Recently Acquired Regulatory Functions

(2012) L. D. Ward et al.   SCIENCE

ENCODE Project Writes Eulogy for Junk DNA

(2012) E. Pennisi   SCIENCE

Rapid Turnover of Functional Sequence in Human and Other Genomes

(2011) Chris P. Ponting et al.   Annual Review of Genomics and Human Genetics

What fraction of the human genome is functional?

(2011) C. P. Ponting et al.   GENOME RESEARCH

Diversification at Transcription Factor Binding Sites within a Species and the Implications for Environmental Adaptation

(2011) R. M. Ames et al.   MOLECULAR BIOLOGY AND EVOLUTION

Human-specific loss of regulatory DNA and the evolution of human-specific traits

(2011) Cory Y. McLean et al.   NATURE

A high-resolution map of human evolutionary constraint using 29 mammals

(2011) Kerstin Lindblad-Toh et al.   NATURE

The evolution of gene expression levels in mammalian organs

(2011) David Brawand et al.   NATURE

Large-scale discovery of enhancers from human heart tissue

(2011) Dalit May et al.   NATURE GENETICS

Three Periods of Regulatory Innovation During Vertebrate Evolution

(2011) C. B. Lowe et al.   SCIENCE

Massive turnover of functional sequence in human and other mammalian genomes

(2010) S. Meader et al.   GENOME RESEARCH

ChIP-Seq identification of weakly conserved heart enhancers

(2010) Matthew J Blow et al.   NATURE GENETICS

Five-Vertebrate ChIP-seq Reveals the Evolutionary Dynamics of Transcription Factor Binding

(2010) D. Schmidt et al.   SCIENCE

Identifying a High Fraction of the Human Genome to be under Selective Constraint Using GERP++

(2010) Eugene V. Davydov et al.   PLoS Computational Biology

Evolution of Primate Gene Expression: Drift and Corrective Sweeps?

(2008) R. Chaix et al.   GENETICS