Enhancer turnover and conserved regulatory function in vertebrate evolution

An Integrated Holo-Enhancer Unit Defines Tissue and Gene Specificity of the Fgf8 Regulatory Landscape

(2013) Mirna Marinić et al.   DEVELOPMENTAL CELL

The zebrafish reference genome sequence and its relationship to the human genome

(2013) Kerstin Howe et al.   NATURE

Differences in enhancer activity in mouse and zebrafish reporter assays are often associated with changes in gene expression

(2012) Ana Ariza-Cosano et al.   BMC GENOMICS

Coding exons function as tissue-specific enhancers of nearby genes

(2012) Ramon Y. Birnbaum et al.   GENOME RESEARCH

Extensive conservation of ancient microsynteny across metazoans due to cis-regulatory constraints

(2012) M. Irimia et al.   GENOME RESEARCH

The Chromatin Fingerprint of Gene Enhancer Elements

(2012) Gabriel E. Zentner et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Obesity-programmed mice are rescued by early genetic intervention

(2012) Viviana F. Bumaschny et al.   JOURNAL OF CLINICAL INVESTIGATION

Neuropeptide Y Stimulates Food Intake in the Zebrafish, Danio rerio

(2012) E. Yokobori et al.   JOURNAL OF NEUROENDOCRINOLOGY

A map of the cis-regulatory sequences in the mouse genome

(2012) Yin Shen et al.   NATURE

Mice Lacking a Myc Enhancer That Includes Human SNP rs6983267 Are Resistant to Intestinal Tumors

(2012) I. K. Sur et al.   SCIENCE

Enhancers as information integration hubs in development: lessons from genomics

(2012) Christa Buecker et al.   TRENDS IN GENETICS

Evolution of POMC: origin, phylogeny, posttranslational processing, and the melanocortins

(2011) Robert M. Dores et al.   Annals of the New York Academy of Sciences

Zebrafish in Endocrine Systems: Recent Advances and Implications for Human Disease

(2011) Heiko Löhr et al.   Annual Review of Physiology

Conserved and non-conserved enhancers direct tissue specific transcription in ancient germ layer specific developmental control genes

(2011) Sumantra Chatterjee et al.   BMC DEVELOPMENTAL BIOLOGY

Fish melanocortin system

(2011) José Miguel Cerdá-Reverter et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Genome-wide identification of conserved regulatory function in diverged sequences

(2011) L. Taher et al.   GENOME RESEARCH

Identification of a chronic obstructive pulmonary disease genetic determinant that regulates HHIP

(2011) Xiaobo Zhou et al.   HUMAN MOLECULAR GENETICS

Ontogeny of the cocaine- and amphetamine-regulated transcript (CART) neuropeptide system in the brain of zebrafish, Danio rerio

(2011) Arghya Mukherjee et al.   JOURNAL OF COMPARATIVE NEUROLOGY

A high-resolution map of human evolutionary constraint using 29 mammals

(2011) Kerstin Lindblad-Toh et al.   NATURE

Large-scale discovery of enhancers from human heart tissue

(2011) Dalit May et al.   NATURE GENETICS

Deletion of a remote enhancer near ATOH7 disrupts retinal neurogenesis, causing NCRNA disease

(2011) Noor M Ghiasvand et al.   NATURE NEUROSCIENCE

Convergent evolution of two mammalian neuronal enhancers by sequential exaptation of unrelated retroposons

(2011) L. F. Franchini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De Novo Genesis of Enhancers in Vertebrates

(2011) Michael P. Eichenlaub et al.   PLOS BIOLOGY

Structural Rules and Complex Regulatory Circuitry Constrain Expression of a Notch- and EGFR-Regulated Eye Enhancer

(2010) Christina I. Swanson et al.   DEVELOPMENTAL CELL

Genome-wide discovery of human heart enhancers

(2010) L. Narlikar et al.   GENOME RESEARCH

Origins, evolution, and phenotypic impact of new genes

(2010) H. Kaessmann   GENOME RESEARCH

Homotypic clusters of transcription factor binding sites are a key component of human promoters and enhancers

(2010) V. Gotea et al.   GENOME RESEARCH

The Importance of Being Cis: Evolution of Orthologous Fish and Mammalian Enhancer Activity

(2010) Deborah I. Ritter et al.   MOLECULAR BIOLOGY AND EVOLUTION

A Pituitary-Specific Enhancer of the POMC Gene with Preferential Activity in Corticotrope Cells

(2010) David Langlais et al.   MOLECULAR ENDOCRINOLOGY

ChIP-Seq identification of weakly conserved heart enhancers

(2010) Matthew J Blow et al.   NATURE GENETICS

Long-range function of an intergenic retrotransposon

(2010) W. Pi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Regulation of Proopiomelanocortin Gene Expression

(2009) Bruce G. Jenks   Annals of the New York Academy of Sciences

Expression of leptin receptor gene in developing and adult zebrafish

(2009) Qin Liu et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Distribution of growth hormone-releasing hormone-like peptide: Immunoreactivity in the central nervous system of the adult zebrafish (Danio rerio)

(2009) Antonio Castro et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Histone modifications at human enhancers reflect global cell-type-specific gene expression

(2009) Nathaniel D. Heintzman et al.   NATURE

ChIP-seq accurately predicts tissue-specific activity of enhancers

(2009) Axel Visel et al.   NATURE

Highly conserved non-coding elements on either side of SOX9 associated with Pierre Robin sequence

(2009) Sabina Benko et al.   NATURE GENETICS

Neuroendocrine transcriptional programs adapt dynamically to the supply and demand for neuropeptides as revealed in NSF mutant zebrafish

(2009) Deborah M Kurrasch et al.   Neural Development

Evo-Devo and an Expanding Evolutionary Synthesis: A Genetic Theory of Morphological Evolution

(2008) Sean B. Carroll   CELL

Melanocortin peptides affect the motivation to feed in rainbow trout (Oncorhynchus mykiss)

(2008) Joachim Schjolden et al.   GENERAL AND COMPARATIVE ENDOCRINOLOGY

Regulation of a remote Shh forebrain enhancer by the Six3 homeoprotein

(2008) Yongsu Jeong et al.   NATURE GENETICS

Disruption of an AP-2α binding site in an IRF6 enhancer is associated with cleft lip

(2008) Fedik Rahimov et al.   NATURE GENETICS

Metrics of sequence constraint overlook regulatory sequences in an exhaustive analysis at phox2b

(2007) D. M. McGaughey et al.   GENOME RESEARCH