Protein Quantitative Trait Loci Identify Novel Candidates Modulating Cellular Response to Chemotherapy

Genetic Architecture of MicroRNA Expression: Implications for the Transcriptome and Complex Traits

(2012) Eric R. Gamazon et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Genetic association with overall survival of taxane-treated lung cancer patients - a genome-wide association study in human lymphoblastoid cell lines followed by a clinical association study

(2012) Nifang Niu et al.   BMC CANCER

Identification of novel germline polymorphisms governing capecitabine sensitivity

(2012) Peter H. O'Donnell et al.   CANCER

Integration of Cell Line and Clinical Trial Genome-Wide Analyses Supports a Polygenic Architecture of Paclitaxel-Induced Sensory Peripheral Neuropathy

(2012) H. E. Wheeler et al.   CLINICAL CANCER RESEARCH

Sex Differences in Human Lymphoblastoid Cells Sensitivities to Antipsychotic Drugs

(2012) Ayelet Morag et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

DNase I sensitivity QTLs are a major determinant of human expression variation

(2012) Jacob F. Degner et al.   NATURE

A genome-wide association analysis of temozolomide response using lymphoblastoid cell lines shows a clinically relevant association with MGMT

(2012) Chad C. Brown et al.   Pharmacogenetics and Genomics

Whole-genome studies identify solute carrier transporters in cellular susceptibility to paclitaxel

(2012) Uchenna O. Njiaju et al.   Pharmacogenetics and Genomics

Genome-wide miRNA expression profiling of human lymphoblastoid cell lines identifies tentative SSRI antidepressant response biomarkers

(2012) Keren Oved et al.   PHARMACOGENOMICS

Functional genetic screen of human diversity reveals that a methionine salvage enzyme regulates inflammatory cell death

(2012) D. C. Ko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Contribution of RNA Decay Quantitative Trait Loci to Inter-Individual Variation in Steady-State Gene Expression Levels

(2012) Athma A. Pai et al.   PLoS Genetics

Mixed Effects Modeling of Proliferation Rates in Cell-Based Models: Consequence for Pharmacogenomics and Cancer

(2012) Hae Kyung Im et al.   PLoS Genetics

Unraveling the Regulatory Mechanisms Underlying Tissue-Dependent Genetic Variation of Gene Expression

(2012) Jingyuan Fu et al.   PLoS Genetics

Patterns of Cis Regulatory Variation in Diverse Human Populations

(2012) Barbara E. Stranger et al.   PLoS Genetics

Dissecting the regulatory architecture of gene expression QTLs

(2012) Daniel J Gaffney et al.   GENOME BIOLOGY

SMC1A codon 496 mutations affect the cellular response to genotoxic treatments

(2011) Linda Mannini et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Src family kinases and paclitaxel sensitivity

(2011) Xiao-Feng Le et al.   CANCER BIOLOGY & THERAPY

Toward a comprehensive characterization of the phosphotyrosine proteome

(2011) Sara Bergström Lind et al.   CELLULAR SIGNALLING

Platinum Sensitivity–Related Germline Polymorphism Discovered via a Cell-Based Approach and Analysis of Its Association with Outcome in Ovarian Cancer Patients

(2011) R. Stephanie Huang et al.   CLINICAL CANCER RESEARCH

Targeted protein-omic methods are bridging the gap between proteomic and hypothesis-driven protein analysis approaches

(2011) Ronald J Hause et al.   Expert Review of Proteomics

An eQTL-based method identifies CTTN and ZMAT3 as pemetrexed susceptibility markers

(2011) Yujia Wen et al.   HUMAN MOLECULAR GENETICS

PI3K/Akt and MAPK/ERK1/2 signaling pathways are involved in IGF-1-induced VEGF-C upregulation in breast cancer

(2011) Chenfang Zhu et al.   JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY

Gene expression analysis in lymphoblastoid cells as a potential biomarker of bipolar disorder

(2011) Tadafumi Kato et al.   JOURNAL OF HUMAN GENETICS

Lymphoblastoid cell lines in pharmacogenomic discovery and clinical translation

(2011) Heather E Wheeler et al.   PHARMACOGENOMICS

Genome-wide meta-analysis identifies variants associated with platinating agent susceptibility across populations

(2011) H E Wheeler et al.   PHARMACOGENOMICS JOURNAL

Germline polymorphisms discovered via a cell-based, genome-wide approach predict platinum response in head and neck cancers

(2011) Dana Ziliak et al.   Translational Research

DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines

(2011) Jordana T Bell et al.   GENOME BIOLOGY

Genome-Wide siRNA Screen for Modulators of Cell Death Induced by Proteasome Inhibitor Bortezomib

(2010) Siquan Chen et al.   CANCER RESEARCH

Sequence signatures and mRNA concentration can explain two-thirds of protein abundance variation in a human cell line

(2010) Christine Vogel et al.   Molecular Systems Biology

Understanding mechanisms underlying human gene expression variation with RNA sequencing

(2010) Joseph K. Pickrell et al.   NATURE

Systems analysis of EGF receptor signaling dynamics with microwestern arrays

(2010) Mark F Ciaccio et al.   NATURE METHODS

Chemotherapeutic drug susceptibility associated SNPs are enriched in expression quantitative trait loci

(2010) E. R. Gamazon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trait-Associated SNPs Are More Likely to Be eQTLs: Annotation to Enhance Discovery from GWAS

(2010) Dan L. Nicolae et al.   PLoS Genetics

Spectrum and consequences ofSMC1Amutations: The unexpected involvement of a core component of cohesin in human disease

(2009) Linda Mannini et al.   HUMAN MUTATION

Dose-Modified Oral Chemotherapy in the Treatment of AIDS-Related Non-Hodgkin's Lymphoma in East Africa

(2009) Walter O. Mwanda et al.   JOURNAL OF CLINICAL ONCOLOGY

Genetic Architecture of Transcript-Level Variation in Humans

(2008) Shiwei Duan et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Evaluation of Genetic Variation Contributing to Differences in Gene Expression between Populations

(2008) Wei Zhang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Population-specific genetic variants important in susceptibility to cytarabine arabinoside cytotoxicity

(2008) C. M. Hartford et al.   BLOOD

Effect of tumor suppressor gene PTEN on the resistance to cisplatin in human ovarian cancer cell lines and related mechanisms

(2008) HuiJuan Wu et al.   CANCER LETTERS

Chromatid cohesion defects may underlie chromosome instability in human colorectal cancers

(2008) T. D. Barber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

High-Resolution Mapping of Expression-QTLs Yields Insight into Human Gene Regulation

(2008) Jean-Baptiste Veyrieras et al.   PLoS Genetics