Src family kinases and paclitaxel sensitivity

SRC: A Century of Science Brought to the Clinic

(2015) Alexey Aleshin et al.   NEOPLASIA

Re-expression of ARHI (DIRAS3) induces autophagy in breast cancer cells and enhances the inhibitory effect of paclitaxel

(2011) Chun-Fang Zou et al.   BMC CANCER

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The involvement of Fyn kinase in resumption of the first meiotic division in mouse oocytes

(2011) Mattan Levi et al.   CELL CYCLE

Functional Roles of Src and Fgr in Ovarian Carcinoma

(2011) H.-S. Kim et al.   CLINICAL CANCER RESEARCH

Dasatinib (BMS-35482) has synergistic activity with paclitaxel and carboplatin in ovarian cancer cells

(2011) Deanna Teoh et al.   GYNECOLOGIC ONCOLOGY

Mitosis is not a key target of microtubule agents in patient tumors

(2011) Edina Komlodi-Pasztor et al.   Nature Reviews Clinical Oncology

Tubulin binding cofactor C (TBCC) suppresses tumor growth and enhances chemosensitivity in human breast cancer cells

(2010) Rouba Hage-Sleiman et al.   BMC CANCER

Breast cancer patients’ clinical outcome measures are associated with Src kinase family member expression

(2010) B Elsberger et al.   BRITISH JOURNAL OF CANCER

Dasatinib induces autophagic cell death in human ovarian cancer

(2010) Xiao-Feng Le et al.   CANCER

Dual targeting of EphA2 and FAK in ovarian carcinoma

(2010) Mian M.K. Shahzad et al.   CANCER BIOLOGY & THERAPY

Targeting pericytes with a PDGF-B aptamer in human ovarian carcinoma models

(2010) Chunhua Lu et al.   CANCER BIOLOGY & THERAPY

Targeting SRC in glioblastoma tumors and brain metastases: Rationale and preclinical studies

(2010) Manmeet S. Ahluwalia et al.   CANCER LETTERS

Specific blockade of VEGF and HER2 pathways results in greater growth inhibition of breast cancer xenografts that overexpress HER2

(2010) Xiao-Feng Le et al.   CELL CYCLE

Src Inhibitors in Lung Cancer: Current Status and Future Directions

(2010) Sacha I. Rothschild et al.   Clinical Lung Cancer

Src redox regulation: Again in the front line

(2010) Elisa Giannoni et al.   FREE RADICAL BIOLOGY AND MEDICINE

MicroRNA-125b Confers the Resistance of Breast Cancer Cells to Paclitaxel through Suppression of Pro-apoptotic Bcl-2 Antagonist Killer 1 (Bak1) Expression

(2010) Ming Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Human Mutations That Confer Paclitaxel Resistance

(2010) S. Yin et al.   MOLECULAR CANCER THERAPEUTICS

Microtubule Dynamics, Mitotic Arrest, and Apoptosis: Drug-Induced Differential Effects of  III-Tubulin

(2010) P. P. Gan et al.   MOLECULAR CANCER THERAPEUTICS

Activity of the multikinase inhibitor dasatinib against ovarian cancer cells

(2009) G E Konecny et al.   BRITISH JOURNAL OF CANCER

The Tensin-3 Protein, Including its SH2 Domain, Is Phosphorylated by Src and Contributes to Tumorigenesis and Metastasis

(2009) Xiaolan Qian et al.   CANCER CELL

Mitotic Deregulation by Survivin in ErbB2-Overexpressing Breast Cancer Cells Contributes to Taxol Resistance

(2009) J. Lu et al.   CLINICAL CANCER RESEARCH

Therapeutic Targeting of ATP7B in Ovarian Carcinoma

(2009) L. S. Mangala et al.   CLINICAL CANCER RESEARCH

The Double-Edged Sword of Autophagy Modulation in Cancer

(2009) E. White et al.   CLINICAL CANCER RESEARCH

Lysophosphatidic acid receptor 2 and Gi/Src pathway mediate cell motility through cyclooxygenase 2 expression in CAOV-3 ovarian cancer cells

(2009) Kang Jin Jeong et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

Larotaxel: broadening the road with new taxanes

(2009) Otto Metzger-Filho et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Increased levels of copper efflux transporter ATP7B are associated with poor outcome in colorectal cancer patients receiving oxaliplatin-based chemotherapy

(2009) Eva Martinez-Balibrea et al.   INTERNATIONAL JOURNAL OF CANCER

Phase II Evaluation of Nanoparticle Albumin–Bound Paclitaxel in Platinum-Sensitive Patients With Recurrent Ovarian, Peritoneal, or Fallopian Tube Cancer

(2009) Michael G. Teneriello et al.   JOURNAL OF CLINICAL ONCOLOGY

Evaluation of Microtubule-Associated Protein-Tau Expression As a Prognostic and Predictive Marker in the NSABP-B 28 Randomized Clinical Trial

(2009) Lajos Pusztai et al.   JOURNAL OF CLINICAL ONCOLOGY

The role of Fyn kinase in the release from metaphase in mammalian oocytes

(2009) M. Levi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Survivin counteracts the therapeutic effect of microtubule de-stabilizers by stabilizing tubulin polymers

(2009) Chun Hei Antonio Cheung et al.   Molecular Cancer

Src Promotes Survival and Invasion of Lung Cancers with Epidermal Growth Factor Receptor Abnormalities and Is a Potential Candidate for Molecular-Targeted Therapy

(2009) E. L.-H. Leung et al.   MOLECULAR CANCER RESEARCH

Dasatinib-induced autophagy is enhanced in combination with temozolomide in glioma

(2009) V. Milano et al.   MOLECULAR CANCER THERAPEUTICS

Triptolide is an inhibitor of RNA polymerase I and II-dependent transcription leading predominantly to down-regulation of short-lived mRNA

(2009) S. Vispe et al.   MOLECULAR CANCER THERAPEUTICS

Src kinases as therapeutic targets for cancer

(2009) Lori C. Kim et al.   Nature Reviews Clinical Oncology

The Role of Src in Solid Tumors

(2009) D. L. Wheeler et al.   ONCOLOGIST

β-Arrestin links endothelin A receptor to β-catenin signaling to induce ovarian cancer cell invasion and metastasis

(2009) Laura Rosanò et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Src as a potential therapeutic target in non-small-cell lung cancer

(2008) G. Giaccone et al.   ANNALS OF ONCOLOGY

Targeting Src in breast cancer

(2008) R. S. Finn   ANNALS OF ONCOLOGY

Non-anti-mitotic concentrations of taxol reduce breast cancer cell invasiveness

(2008) Truong-An Tran et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Grp94 is Tyr-phosphorylated by Fyn in the lumen of the endoplasmic reticulum and translocates to Golgi in differentiating myoblasts

(2008) Martina Frasson et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Role of PELP1/MNAR Signaling in Ovarian Tumorigenesis

(2008) C. Dimple et al.   CANCER RESEARCH

Autophagy in the Pathogenesis of Disease

(2008) Beth Levine et al.   CELL

Synergistic Antitumor Activity of Ixabepilone (BMS-247550) Plus Bevacizumab in Multiple In vivo Tumor Models

(2008) F. Y.F. Lee et al.   CLINICAL CANCER RESEARCH

Combined Inhibition of c-Src and Epidermal Growth Factor Receptor Abrogates Growth and Invasion of Head and Neck Squamous Cell Carcinoma

(2008) P. Koppikar et al.   CLINICAL CANCER RESEARCH

Copper Transport Systems are Involved in Multidrug Resistance and Drug Transport

(2008) Tatsuhiko Furukawa et al.   CURRENT MEDICINAL CHEMISTRY

Src inhibitors in breast cancer therapy

(2008) Stephen Hiscox et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Lysophosphatidic acid induces ovarian cancer cell dispersal by activating Fyn kinase associated with p120-catenin

(2008) Ruby Yun-Ju Huang et al.   INTERNATIONAL JOURNAL OF CANCER

MRP7/ABCC10 expression is a predictive biomarker for the resistance to paclitaxel in non-small cell lung cancer

(2008) T. Oguri et al.   MOLECULAR CANCER THERAPEUTICS

The Lipid Raft-Anchored Adaptor Protein Cbp Controls the Oncogenic Potential of c-Src

(2008) Chitose Oneyama et al.   MOLECULAR CELL

Targeting Epidermal Growth Factor Receptor and Src Pathways in Head and Neck Cancer

(2008) Ann Marie Egloff et al.   SEMINARS IN ONCOLOGY

Src as a Therapeutic Target in Breast Cancer

(2008) Liam Morgan et al.   Endocrine Metabolic & Immune Disorders-Drug Targets

Src family kinases: Regulation of their activities, levels and identification of new pathways

(2007) Evan Ingley   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS