Heterologous Gln/Asn-Rich Proteins Impede the Propagation of Yeast Prions by Altering Chaperone Availability

An intrinsically disordered yeast prion arrests the cell cycle by sequestering a spindle pole body component

(2012) Sebastian Treusch et al.   JOURNAL OF CELL BIOLOGY

Hsp70 targets Hsp100 chaperones to substrates for protein disaggregation and prion fragmentation

(2012) Juliane Winkler et al.   JOURNAL OF CELL BIOLOGY

Chaperone networks in protein disaggregation and prion propagation

(2012) Juliane Winkler et al.   JOURNAL OF STRUCTURAL BIOLOGY

Influence of prion variant and yeast strain variation on prion-molecular chaperone requirements

(2012) Justin K. Hines et al.   Prion

A new perspective on Hsp104-mediated propagation and curing of the yeast prion [PSI+]

(2012) Christopher W. Helsen et al.   Prion

A Yeast Prion, Mod5, Promotes Acquired Drug Resistance and Cell Survival Under Environmental Stress

(2012) G. Suzuki et al.   SCIENCE

Polyglutamine Toxicity Is Controlled by Prion Composition and Gene Dosage in Yeast

(2012) He Gong et al.   PLoS Genetics

[PSI+] aggregate enlargement in rnq1 nonprion domain mutants, leading to a loss of prion in yeast

(2011) Hiroshi Kurahashi et al.   GENES TO CELLS

Yeast prion protein New1 can break Sup35 amyloid fibrils into fragments in an ATP-dependent manner

(2011) Yuji Inoue et al.   GENES TO CELLS

Molecular Chaperone Hsp104 Can Promote Yeast Prion Generation

(2011) Dmitry S. Kryndushkin et al.   GENETICS

Insight into Molecular Basis of Curing of [PSI+] Prion by Overexpression of 104-kDa Heat Shock Protein (Hsp104)

(2011) Christopher W. Helsen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Opposing Effects of Glutamine and Asparagine Govern Prion Formation by Intrinsically Disordered Proteins

(2011) Randal Halfmann et al.   MOLECULAR CELL

Dominant prion mutants induce curing through pathways that promote chaperone-mediated disaggregation

(2011) Susanne DiSalvo et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Newly identified prions in budding yeast, and their possible functions

(2011) Emily T. Crow et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

A new colour assay for [URE3] prion in a genetic background used to score for the [PSI+] prion

(2011) Joo Y. Hong et al.   YEAST

[SWI+], the Prion Formed by the Chromatin Remodeling Factor Swi1, Is Highly Sensitive to Alterations in Hsp70 Chaperone System Activity

(2011) Justin K. Hines et al.   PLoS Genetics

Influence of Hsp70s and their regulators on yeast prion propagation

(2010) Daniel C. Masison et al.   Prion

The effects of amino acid composition on yeast prion formation and prion domain interactions

(2010) Eric D. Ross et al.   Prion

A Size Threshold Limits Prion Transmission and Establishes Phenotypic Diversity

(2010) Aaron Derdowski et al.   SCIENCE

Increased [PSI+] Appearance by Fusion of Rnq1 with the Prion Domain of Sup35 inSaccharomyces cerevisiae

(2009) Young-Jun Choe et al.   EUKARYOTIC CELL

Single mother-daughter pair analysis to clarify the diffusion properties of yeast prion Sup35 in guanidine-HCl-treated [PSI+] cells

(2009) Shigeko Kawai-Noma et al.   GENES TO CELLS

Ssa1 Overexpression and [PIN+] Variants Cure [PSI+] by Dilution of Aggregates

(2009) Vidhu Mathur et al.   JOURNAL OF MOLECULAR BIOLOGY

Reciprocal Efficiency of RNQ1 and Polyglutamine Detoxification in the Cytosol and Nucleus

(2009) Peter M. Douglas et al.   MOLECULAR BIOLOGY OF THE CELL

Sequestration of essential proteins causes prion associated toxicity in yeast

(2009) Namitha Vishveshwara et al.   MOLECULAR MICROBIOLOGY

A G-protein γ subunit mimic is a general antagonist of prion propagation in Saccharomyces cerevisiae

(2009) Masao Ishiwata et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Life Cycle of Yeast Prions: Propagation Mediated by Amyloid Fibrils

(2009) Yuji Inoue   PROTEIN AND PEPTIDE LETTERS

Hsp104 and Prion Propagation

(2009) Nina Romanova et al.   PROTEIN AND PEPTIDE LETTERS

Insights into the mechanism of prion propagation

(2008) Sarah Perrett et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Impaired ERAD and ER stress are early and specific events in polyglutamine toxicity

(2008) M. L. Duennwald et al.   GENES & DEVELOPMENT

A Regulatory Role of the Rnq1 Nonprion Domain for Prion Propagation and Polyglutamine Aggregates

(2008) H. Kurahashi et al.   MOLECULAR AND CELLULAR BIOLOGY

Variant-specific [PSI+] Infection Is Transmitted by Sup35 Polymers within [PSI+] Aggregates with Heterogeneous Protein Composition

(2008) Sviatoslav N. Bagriantsev et al.   MOLECULAR BIOLOGY OF THE CELL

In Vivo Monitoring of the Prion Replication Cycle Reveals a Critical Role for Sis1 in Delivering Substrates to Hsp104

(2008) Kimberly A. Tipton et al.   MOLECULAR CELL

Substrate threading through the central pore of the Hsp104 chaperone as a common mechanism for protein disaggregation and prion propagation

(2008) Peter Tessarz et al.   MOLECULAR MICROBIOLOGY

Hsp110 Chaperones Regulate Prion Formation and Propagation in S. cerevisiae by Two Discrete Activities

(2008) Heather Sadlish et al.   PLoS One

Specificity of the J-protein Sis1 in the propagation of 3 yeast prions

(2008) T. Higurashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chaperone-dependent amyloid assembly protects cells from prion toxicity

(2008) P. M. Douglas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA