Preferential Binding to Elk-1 by SLE-Associated IL10 Risk Allele Upregulates IL10 Expression

Regulatory B cells in autoimmune diseases

(2013) Min Yang et al.   Cellular & Molecular Immunology

Meta-analysis Followed by Replication Identifies Loci in or near CDKN1B, TET3, CD80, DRAM1, and ARID5B as Associated with Systemic Lupus Erythematosus in Asians

(2012) Wanling Yang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Biological properties and regulation of IL-10 related cytokines and their contribution to autoimmune disease and tissue injury

(2012) S.R. Hofmann et al.   CLINICAL IMMUNOLOGY

Carabin deficiency in B cells increases BCR-TLR9 costimulation-induced autoimmunity

(2012) Jean-Nicolas Schickel et al.   EMBO Molecular Medicine

Elk-1 phosphorylated at threonine-417 is present in diverse cancers and correlates with differentiation grade of colonic adenocarcinoma

(2012) Jacqueline F. Morris et al.   HUMAN PATHOLOGY

Interaction of Ets-1 with HDAC1 Represses IL-10 Expression in Th1 Cells

(2012) C.-G. Lee et al.   JOURNAL OF IMMUNOLOGY

Genetics of gene expression in primary immune cells identifies cell type–specific master regulators and roles of HLA alleles

(2012) Benjamin P Fairfax et al.   NATURE GENETICS

Chromatin marks identify critical cell types for fine mapping complex trait variants

(2012) Gosia Trynka et al.   NATURE GENETICS

Mapping cis- and trans-regulatory effects across multiple tissues in twins

(2012) Elin Grundberg et al.   NATURE GENETICS

ELK1 Uses Different DNA Binding Modes to Regulate Functionally Distinct Classes of Target Genes

(2012) Zaneta Odrowaz et al.   PLoS Genetics

A Genome-Wide Association Study Identified AFF1 as a Susceptibility Locus for Systemic Lupus Eyrthematosus in Japanese

(2012) Yukinori Okada et al.   PLoS Genetics

Patterns of Cis Regulatory Variation in Diverse Human Populations

(2012) Barbara E. Stranger et al.   PLoS Genetics

The effect of IL-10 genetic variation and interleukin 10 serum levels on Crohn's disease susceptibility in a New Zealand population

(2011) Alice H. Wang et al.   HUMAN IMMUNOLOGY

Regulatory T-Cell-Associated Cytokines in Systemic Lupus Erythematosus

(2011) Akiko Okamoto et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

B Cell-Derived IL-10 Does Not Regulate Spontaneous Systemic Autoimmunity in MRL.Faslpr Mice

(2011) L. L. Teichmann et al.   JOURNAL OF IMMUNOLOGY

Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47

(2011) Carl A Anderson et al.   NATURE GENETICS

B cell-derived IL-10 suppresses inflammatory disease in Lyn-deficient mice

(2011) P. Scapini et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The use of Systemic Lupus Erythematosus Disease Activity Index-2000 to define active disease and minimal clinically meaningful change based on data from a large cohort of systemic lupus erythematosus patients

(2011) C.-S. Yee et al.   RHEUMATOLOGY

Genome-Wide Association Analysis of Autoantibody Positivity in Type 1 Diabetes Cases

(2011) Vincent Plagnol et al.   PLoS Genetics

Identification of a Systemic Lupus Erythematosus Susceptibility Locus at 11p13 between PDHX and CD44 in a Multiethnic Study

(2010) Christopher J. Lessard et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A functional RANKL polymorphism associated with younger age at onset of rheumatoid arthritis

(2010) Wenfeng Tan et al.   ARTHRITIS AND RHEUMATISM

Characterization of a rare IL-10-competent B-cell subset in humans that parallels mouse regulatory B10 cells

(2010) Y. Iwata et al.   BLOOD

Circulating antiinflammatory cytokine IL-10 in patients with inflammatory bowel disease (IBD)

(2010) T. KUCHARZIK et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients

(2010) Paul A. Blair et al.   IMMUNITY

Protective and Pathogenic Roles for B Cells during Systemic Autoimmunity in NZB/W F1 Mice

(2010) K. M. Haas et al.   JOURNAL OF IMMUNOLOGY

Regulatory B Cells (B10 Cells) Have a Suppressive Role in Murine Lupus: CD19 and B10 Cell Deficiency Exacerbates Systemic Autoimmunity

(2010) R. Watanabe et al.   JOURNAL OF IMMUNOLOGY

Genome-wide association studies identify IL23R-IL12RB2 and IL10 as Behçet's disease susceptibility loci

(2010) Nobuhisa Mizuki et al.   NATURE GENETICS

Genome-wide association study identifies variants in the MHC class I, IL10 and IL23R-IL12RB2 regions associated with Behçet's disease

(2010) Elaine F Remmers et al.   NATURE GENETICS

Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci

(2010) Andre Franke et al.   NATURE GENETICS

A Neurotoxic Phosphoform of Elk-1 Associates with Inclusions from Multiple Neurodegenerative Diseases

(2010) Anup Sharma et al.   PLoS One

Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus

(2010) Wanling Yang et al.   PLoS Genetics

Proinflammatory cytokines and IL-10 in inflammatory bowel disease and colorectal cancer patients

(2009) Andrzej Szkaradkiewicz et al.   ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS

Activation Profile of Intracellular Mitogen-Activated Protein Kinases in Peripheral Lymphocytes of Patients with Systemic Lupus Erythematosus

(2009) Chun K. Wong et al.   JOURNAL OF CLINICAL IMMUNOLOGY

Selective Targeting of B Cells with Agonistic Anti-CD40 Is an Efficacious Strategy for the Generation of Induced Regulatory T2-Like B Cells and for the Suppression of Lupus in MRL/lpr Mice

(2009) P. A. Blair et al.   JOURNAL OF IMMUNOLOGY

A large-scale replication study identifies TNIP1, PRDM1, JAZF1, UHRF1BP1 and IL10 as risk loci for systemic lupus erythematosus

(2009) Vesela Gateva et al.   NATURE GENETICS

Genome-wide association study in a Chinese Han population identifies nine new susceptibility loci for systemic lupus erythematosus

(2009) Jian-Wen Han et al.   NATURE GENETICS

Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes

(2009) Jeffrey C Barrett et al.   NATURE GENETICS

Inflammatory Bowel Disease and Mutations Affecting the Interleukin-10 Receptor

(2009) Erik-Oliver Glocker et al.   NEW ENGLAND JOURNAL OF MEDICINE

Common Regulatory Variation Impacts Gene Expression in a Cell Type-Dependent Manner

(2009) A. S. Dimas et al.   SCIENCE

A Flexible and Accurate Genotype Imputation Method for the Next Generation of Genome-Wide Association Studies

(2009) Bryan N. Howie et al.   PLoS Genetics

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

(2008) Andre Franke et al.   NATURE GENETICS