Inflammation-Mediated Genetic and Epigenetic Alterations Drive Cancer Development in the Neighboring Epithelium upon Stromal Abrogation of TGF-β Signaling

Molecular Pathways: Pathogenesis and Clinical Implications of Microbiome Alteration in Esophagitis and Barrett Esophagus

(2012) L. Yang et al.   CLINICAL CANCER RESEARCH

DNA breaks and chromosome pulverization from errors in mitosis

(2012) Karen Crasta et al.   NATURE

Deletion of p120-Catenin Results in a Tumor Microenvironment with Inflammation and Cancer that Establishes It as a Tumor Suppressor Gene

(2011) Douglas B. Stairs et al.   CANCER CELL

Pten in the Breast Tumor Microenvironment: Modeling Tumor–Stroma Coevolution: Figure 1.

(2011) Julie A. Wallace et al.   CANCER RESEARCH

Altered TGF-β Signaling in a Subpopulation of Human Stromal Cells Promotes Prostatic Carcinogenesis

(2011) Omar E. Franco et al.   CANCER RESEARCH

Stromal Deletion of the APC Tumor Suppressor in Mice Triggers Development of Endometrial Cancer

(2011) P. S. Tanwar et al.   CANCER RESEARCH

Microbiome and Malignancy

(2011) Claudia S. Plottel et al.   Cell Host & Microbe

Global Gene Expression Profiling and Validation in Esophageal Squamous Cell Carcinoma and Its Association with Clinical Phenotypes

(2011) H. Su et al.   CLINICAL CANCER RESEARCH

Transforming Growth Factor-β in the Gastrointestinal and Hepatic Tumor Microenvironment

(2011) Bhagelu Ram Achyut et al.   GASTROENTEROLOGY

Spontaneous transformation of murine epithelial cells requires the early acquisition of specific chromosomal aneuploidies and genomic imbalances

(2011) Hesed M. Padilla-Nash et al.   GENES CHROMOSOMES & CANCER

Effects of Inflammatory Factors on Mesenchymal Stem Cells and Their Role in the Promotion of Tumor Angiogenesis in Colon Cancer

(2011) Yan Liu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibiting Cxcr2 disrupts tumor-stromal interactions and improves survival in a mouse model of pancreatic ductal adenocarcinoma

(2011) Hideaki Ijichi et al.   JOURNAL OF CLINICAL INVESTIGATION

More than just a focus: The chromatin response to DNA damage and its role in genome integrity maintenance

(2011) Jiri Lukas et al.   NATURE CELL BIOLOGY

Chromosome Segregation Errors as a Cause of DNA Damage and Structural Chromosome Aberrations

(2011) A. Janssen et al.   SCIENCE

Genome wide analysis of DNA copy number neutral loss of heterozygosity (CNNLOH) and its relation to gene expression in esophageal squamous cell carcinoma

(2010) Nan Hu et al.   BMC GENOMICS

TGFβ and cancer metastasis: an inflammation link

(2010) Li Yang   CANCER AND METASTASIS REVIEWS

Histone Post-Translational Modifications in DNA Damage Response

(2010) L. Méndez-Acuña et al.   CYTOGENETIC AND GENOME RESEARCH

Genetic Labeling Does Not Detect Epithelial-to-Mesenchymal Transition of Cholangiocytes in Liver Fibrosis in Mice

(2010) David Scholten et al.   GASTROENTEROLOGY

CpG island methylator phenotype of cell-cycle regulators associated with TNM stage and poor prognosis in patients with oesophageal squamous cell carcinoma

(2010) Y. Ling et al.   JOURNAL OF CLINICAL PATHOLOGY

Fibroblast-specific protein 1 identifies an inflammatory subpopulation of macrophages in the liver

(2010) C. H. Osterreicher et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epidermal Notch1 Loss Promotes Skin Tumorigenesis by Impacting the Stromal Microenvironment

(2009) Shadmehr Demehri et al.   CANCER CELL

MicroRNA Expression in Squamous Cell Carcinoma and Adenocarcinoma of the Esophagus: Associations with Survival

(2009) E. A. Mathe et al.   CLINICAL CANCER RESEARCH

Autoimmune pancreatitis results from loss of TGF  signalling in S100A4-positive dendritic cells

(2009) C S Boomershine et al.   GUT

Abrogation of TGF-β signaling enhances chemokine production and correlates with prognosis in human breast cancer

(2009) Brian Bierie et al.   JOURNAL OF CLINICAL INVESTIGATION

Pten in stromal fibroblasts suppresses mammary epithelial tumours

(2009) Anthony J. Trimboli et al.   NATURE

SOX2 is an amplified lineage-survival oncogene in lung and esophageal squamous cell carcinomas

(2009) Adam J Bass et al.   NATURE GENETICS

Transforming Growth Factor-  Regulates Mammary Carcinoma Cell Survival and Interaction with the Adjacent Microenvironment

(2008) B. Bierie et al.   CANCER RESEARCH

Transforming Growth Factor-  Signaling-Deficient Fibroblasts Enhance Hepatocyte Growth Factor Signaling in Mammary Carcinoma Cells to Promote Scattering and Invasion

(2008) N. Cheng et al.   MOLECULAR CANCER RESEARCH

Stromal gene expression predicts clinical outcome in breast cancer

(2008) Greg Finak et al.   NATURE MEDICINE

Prostate tumor progression is mediated by a paracrine TGF-β/Wnt3a signaling axis

(2008) X Li et al.   ONCOGENE